Corporate Magazine 2012 - Boehringer Ingelheim

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product portfoliobranded prescription medicinesIndications Brand names Active ingredients• Type 2 diabetes mellitustrajenta®tradjenta®trazenta®trayenta®linagliptinTreatment of type 2 diabetes mellitus toimprove glycaemic control in adults. Itmay be used as monotherapy or in combinationtherapy.• Type 2 diabetes mellitusjentadueto®trayenta duo®linagliptin, metformin hydrochlorideTreatment of type 2 diabetes mellitus toimprove glycaemic control in adultswhen treatment with both linagliptinand metformin is appropriate.Indications Brand names Active ingredients• HIV/AIDSviramune® xrviramune xr®viramune® prolongedrelease tabletsnevirapineAvailable as tablets and suspension foradults and children – for the combinationtherapy of HIV-1 infection and (inseveral countries) for the prevention ofmother-to-child transmission of HIV-1in pregnant women who are not takingantiretroviral therapy at time of labour.Prolonged release tablets for once-dailydosing within combination therapy.• HIV/AIDS aptivus® tipranavir Capsule and oral solution – co-administeredwith 200 mg of ritonavir, is indicatedfor combination antiretroviraltreatment of HIV-1-infected patientswith evidence of viral replication, whoare treatment-experienced and infectedwith HIV-1 strains resistant to more thanone protease inhibitor.Metabolic diseases / Infectious diseases79
Cough and coldmucosolvan® (ambroxol) and bisolvon® (bromhexine)are both indicated for secretolytic therapy in bronchopulmonarydiseases associated with abnormal mucussecretion and impaired mucus transport.Cough is the most common symptom of clinical importanceand a frequent reason for consulting a doctor orvisiting a pharmacy. The clinical symptoms of coughand expectoration have led to the development of drugsthat affect respiratory mucus, i. e. the mucoactive agents.mucosolvan® (ambroxol), which promotes mucus clearance,facilitates expectoration and eases productivecough, allowing patients to breathe freely and deeply, isthe world’s leading cough brand. It is available in manydifferent product forms and formulations.body’s natural defence mechanisms. Ambroxol alsostimulates synthesis and release of surfactant by type IIpneumocytes.bisolvon® (bromhexine), available for all age groups,has been on the market since 1963. Bromhexine is containedin various formulations of bisolvon®. There arehigh- and low-strength syrups 8 mg/5 ml, 4 mg/5 ml,tablets and soluble tablets (both with 8 mg bromhexine)and solution for oral use (10 mg/5 ml), adapted to patients’needs. Bromhexine is a synthetic derivative of theherbal active ingredient vasicine. It has been shown toincrease the proportion of serious bronchial secretion,making it more easily expectorated. Bromhexine alsoenhances mucus transport by reducing mucus viscosityand by activating the ciliated epithelium.Ambroxol is a mucoactive drug with several properties,including secretolytic and secretomotoric actions thatrestore the physiological clearance mechanisms of therespiratory tract, which play an important role in theSore throatmucoangin® is the best documented product in its categoryof pain relief in acute sore throat.Pain in sore throat is the hallmark of acute pharyngitis,usually caused by a viral infection. The infection is, as arule, self-limited and the patient normally recovers in acouple of days. What is most bothersome for the patientis the continuous pain in the throat, which is maximisedwhen swallowing. The main goal of the treatment isthus to reduce pain.In addition to its secretolytic activity, ambroxol is a verypotent inhibitor of the neuronal sodium channels.Therefore mucoangin® (ambroxol) has a strong localanaesthetic effect, described first in the late 1970s, butexplained and confirmed in more recent work.80Boehringer Ingelheim annual report 2012
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Value through InnovationCorporate M
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our businesses66 [ prescription med
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value through innovationperspective
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56° 40' 59" N, 5° 6' 14" Wglencoe
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56° 40' 59" N, 5° 6' 14" Wglencoe
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PERSPECTIVES FORSOCIETYIn all our a
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50 NATIONSPeople from around 50 nat
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“RLDP journey: a great learning o
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SHONA MCDONALD, SHONAQUIP[ south af
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SEHNAZ LAYIKEL, RUSIHAK[ turkey ]he
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Thalita Guimaraes joins the “Boeh
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When handling chemicals, employees
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11 With its own wastewater treatmen
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21 Dr Carolyn R. Bertozzi received
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PERSPECTIVES FOR THE SOCIETYOF TOMO
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The opening ceremony of IMB:Interac
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CIRCUIT MECHANICS OF EMOTIONSUnders
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BIBERACH UNIVERSITY OF APPLIEDSCIEN
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22° 41' 0" S, 14° 32' 0" Eswakopm
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22° 41' 0" S, 14° 32' 0" Eswakopm
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PERSPECTIVES FORMEDICAL INNOVATIONB
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RESEARCH PARTNERSHIPS WITHACADEMIA
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collaborate innovate accelerateTRAN
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GLORIA-AF®Registry programme for p
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BOEHRINGER INGELHEIM ONCOLOGY FRANC
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AFATINIB BLOCKS THE ERBB RECEPTORSE
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HEPTATIS C VIRUS (HCV) INFECTIONHCV
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1viral entryrnareleasernatranslated
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12THE MAIN COMPLICATIONS OF DIABETE
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ASTHMAAsthma is a chronic disease c
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THERAPEUTIC AREA (TA) REVIEW CORE T
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6° 59' 15" N, 125° 16' 15" Eapo,
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icardo f. solitariadistrict manager
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PERSPECTIVES FORBETTER HEALTHBoehri
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“My photo shows Frau Röhrigfrom
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OUR CARDIOVASCULAR PORTFOLIOaggreno
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HOW ATRIAL FIBRILLATION (AF)LEADS T
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FINDING THE RIGHT MOLECULE“Findin
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PATIENTS AT CARDIOVASCULAR RISKMost
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TRAJENTA® / TRADJENTA®trajenta®
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WORLD DIABETES DAYWorld Diabetes Da
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SPIRIVA®: 10 YEARS AND MORE OF CLI
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BEHAVIOUR CHANGE INTYPE 2 DIABETEST
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Rapid progress in global healthcare
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KEY GOALS OF GLOBAL BUSINESS SERVIC
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“The perspectives that open upune
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OUR GLOBAL SWITCH TEAMThe Switch un
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“For me, the photo shows thatthe
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2 Disposable single use bioreactorw
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“The hard-working beessuccessfull
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“There are many things and experi
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OUR GLOBAL SCIENTIFIC NET WORKIN AN
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2 31 Scientists in Hannover working
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“Living and working on a differen
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1 Phoenix, the first captive-bredOr
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55° 21' 0" N, 131° 40' 24" Wketch
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scott zhangstrategic effectiveness
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PERSPECTIVES FORQUALITY IN OPERATIO
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With the quality risk management sy
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In order to ensure patient safety,
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37° 34' 48" N, 14° 16' 34" Esicil
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37° 34' 48" N, 14° 16' 34" Esicil
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PERSPECTIVES FORESTABLISHED MARKETS
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Spain is one of the countries struc
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21 View of Athens.2 Production site
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1 View of San Francisco, the leadin
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211 View of Tokyo with Japan’s hi
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IF YOU HAVE ANY QUERIES OR COMMENTS
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Value through InnovationBusiness Ye
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product portfolio70 [ branded presc
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usiness year 2012our companyOUR COM
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usiness year 2012the shareholders
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usiness year 2012 key aspects 2012S
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