Corporate Magazine 2012 - Boehringer Ingelheim

Gastrointestinal diseasesIn our gastrointestinal portfolio, we offer several brandssuch as dulcolax®, surulac®, laxoberal®, guttalax®,buscopan®, as well as the heartburn brands zantac®and buscopan® antiacido and gastol®.Constipation is a common problem. dulcolax® is theleading over-the-counter (OTC) laxative remedy forconstipation relief worldwide.Within the dulcolax® franchise, Boehringer Ingelheimmarkets a range of products for the treatment, regulationand prevention of intestinal irregularity and disruption.The primary ailment within this area is constipation,for which dulcolax® tablets are today the mainmethod of treatment.dulcolax® tablets have a special enteric “comfortcoating” which ensures that the active ingredient indulcolax® tablets, bisacodyl, is taken to where it needsto act – the colon. Here, in the colon, the colonic juicesactivate the key ingredient, which then relieves constipation.It stimulates the natural movement of the bowelsto provide gentle, predictable relief within 6 –12 hours.One to two tablets taken before going to bed will stillprovide relief the next morning.dulcolax® is specifically formulated to provide effective,predictable relief for constipation. dulcolax® offersa reliable range of products.Abdominal cramping, pain and discomfort are commonailments. Approximately one in four persons worldwidesuffers on a regular basis.buscopan® is an antispasmodic product with the activeingredient hyoscine butylbromide. The product is basicallya natural substance extracted from Duboisia plant speciesas scopolamine (hyoscine) and chemically modifiedto the quaternary ammonium compound hyoscine butylbromide.As an antispasmodic product, buscopan® actsdirectly on the site of abdominal pain by relaxing thesmooth muscles of the gastrointestinal, biliary, urinaryand genital tracts.This means buscopan® relieves abdominal pain by directlytreating its main cause – abdominal cramp orspasm.Several buscopan® line extensions are available today –the mono-variant and different combinations withanalgesics (paracetamol, ibuprofen and metamizol/dipyrone)– and different formulations (tablets, drops, suppositories,syrup and solutions for intravenous injection).The umbrella brand buscopan® also offers buscofem®for mentstrul pain relief, buscopan® antiacido andbuscopan® reflusso for heartburn relief.Other products within the dulcolax® range includedulcoease® (stool softener), dulcoenema®,dulcobalance® and dulcogas®.surulac® is the constipation brand in Japan, whereconsumers are offered surulac® as a laxative tablet.laxoberal® and guttalax® are the brands offeringconsumers constipation relief with a unique and flexibledosage format – namely drops.82Boehringer Ingelheim annual report 2012