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Neurology Edited by Professor Emeritus Desire' Dubounet, IMUNE

Neurology Edited by Professor Emeritus Desire' Dubounet, IMUNE

Neurology Edited by Professor Emeritus Desire' Dubounet, IMUNE

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Pituitary hormones: anterior lobe (adenohypophysis)The four messenger and the two direct acting hormones of the anteriorThe anterior lobe is site of formation and storage of 6 hormones: 4 messenger hormonesthat act on other endocrine glands:ACTH (→ adrenals: Cushing's syndrome, ↓ Addison's disease)TSH (→ thyroid: hyper-, hypothyroidism)FSH (→ gonads)LH (→ gonads)The two direct acting hormones act on other systems or whole organism:GH (→ all cells of body, gantism or acromegaly)Prolactin (→ many cells: galactorrhoea, secondary amenorrhoea;impotence,gynaecomastia)Control of release of all anterior lobe hormones is exclusively humoral via 6hypothalamic neurohormones (table below)ACTH: adrenocorticotrophic hormone (corticotrophin); TSH: thyroid stimulating hormone(thyrotrophin);-FSH: follicle stimulating hormone; LH: luteinising hormone (both FSH andLH are gonadotrophins); GH: growth hormone, also STH: somatotropic hormone(somatotropin)

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