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Intestinal Ischemia 3-12Pancreatitis 3-13Abnormal Liver Tests 3-15Hepatitis 3-17Acute Liver Failure 3-20Cirrhosis 3-21Hepatic Vascular Disease 3-25Ascites 3-26Biliary Tract Disease 3-27NEPHROLOGYAndrew L. Lundquist, Eugene P. Rhee, Hasan BazariAcid-Base Disturbances 4-1Sodium and Water Homeostasis 4-6Potassium Homeostasis 4-10Renal Failure 4-12Glomerular Disease 4-16Urinalysis 4-18Nephrolithiasis 4-19HEMATOLOGY-ONCOLOGYAndrew J. Aguirre, Franklin W. Huang, David B. Sykes, David T. Ting,Daniel J. DeAngelo, David P. RyanAnemia 5-1Disorders of Hemostasis 5-6Platelet Disorders 5-7Coagulopathies 5-10Hypercoagulable States 5-11Disorders of Leukocytes 5-12Transfusion Therapy 5-13Myelodysplastic Syndromes (MDS) 5-14Myeloproliferative Neoplasms (MPN) 5-15Leukemia 5-17Lymphoma 5-21Plasma Cell Dyscrasias 5-24Hematopoietic Stem Cell Transplantation (HSCT) 5-26Lung Cancer 5-28Breast Cancer 5-30Prostate Cancer 5-32Colorectal Cancer (CRC) 5-33Pancreatic Tumors 5-35Oncologic Emergencies 5-36Cancer of Unknown Primary Site 5-37INFECTIOUS DISEASESRoby P. Bhattacharyya, Rachel P. Simmons, Nesli BasgozPneumonia 6-1Fungal Infections 6-3Infections in S<strong>usc</strong>eptible Hosts 6-4Urinary Tract Infections (UTI) 6-5Soft Tissue and Bone Infections 6-6Infections of the Nervous System 6-9Bacterial Endocarditis 6-12Tuberculosis 6-15
HIV/AIDS 6-17Tick-Borne Diseases 6-21Fever of Unknown Origin (FUO) 6-23ENDOCRINOLOGYAlaka Ray, Geoffrey A.Walford, Michael MannstadtPituitary Disorders 7-1Disorders of Multiple Endocrine Systems 7-2Thyroid Disorders 7-3Adrenal Disorders 7-7Calcium Disorders 7-11Diabetes Mellitus 7-13Lipid Disorders 7-16RHEUMATOLOGYGwen C. Crevensten, Katherine P. Liao, Robert P. FridayArthritis—Overview 8-1Rheumatoid Arthritis (RA) 8-3Relapsing Polychondritis 8-4Crystal Deposition Arthritides 8-5Seronegative Spondyloarthritis 8-7Infectious Arthritis & Bursitis 8-9Connective Tissue Diseases 8-11Systemic Lupus Erythematosus (SLE) 8-15Vasculitis 8-17Cryoglobulinemia 8-21Amyloidosis 8-22NEUROLOGYDavid Y. Hwang, Atul Maheshwari, Mikael L. Rinne, David M. GreerChange in Mental Status 9-1Seizures 9-3Alcohol Withdrawal 9-5Stroke 9-6Weakness & Neurom<strong>usc</strong>ular Dysfunction 9-8Headache 9-10Back and Spinal Cord Disease 9-11APPENDIXACLS Algorithms 10-1ICU Medications 10-4Antibiotics 10-6Formulae and Quick Reference 10-7ABBREVIATIONS 11-1INDEX I-1PHOTO INSERTSRadiology P-1Echocardiography P-9Coronary Angiography P-13Peripheral Blood Smears P-13Leukemias P-14Urinalysis P-15
Page 3 and 4: POCKETNOTEBOOKPocketMEDICINEFourth
Page 5: Contributing AuthorsForewordPreface
Page 9 and 10: Rajat Gupta, MDInternal Medicine Re
Page 11 and 12: FOREWORDTo the 1st EditionIt is wit
Page 13 and 14: ELECTROCARDIOGRAPHYApproach (a syst
Page 15 and 16: CHEST PAINDisorderUnstableanginaMIP
Page 17 and 18: CORONARY ANGIOGRAPHY AND REVASCULAR
Page 19 and 20: Likelihood of ACSFeature High Inter
Page 21 and 22: STEMIReperfusion• Immediate reper
Page 23 and 24: • VT/VF: lido or amio 6-24 h, th
Page 25 and 26: PA Catheter WaveformsLocation RA RV
Page 27 and 28: Evaluation of the causes of heart f
Page 29 and 30: CARDIOMYOPATHIESDiseases with mecha
Page 31 and 32: RESTRICTIVE CARDIOMYOPATHY (RCMP)De
Page 33 and 34: AORTIC INSUFFICIENCY (AI)Etiology (
Page 35 and 36: Clinical manifestations (Lancet 200
Page 37 and 38: PERICARDIAL DISEASEGENERAL PRINCIPL
Page 39 and 40: CONSTRICTIVE PERICARDITISEtiology
Page 41 and 42: • Pharmacologic options (if HTN o
Page 43 and 44: ACUTE AORTIC SYNDROMESDefinitions (
Page 45 and 46: OnsetRateRhythmP wavemorphologyResp
Page 47 and 48: ATRIAL FIBRILLATIONClassification (
Page 49 and 50: SYNCOPEDefinition• Symptom of sud
Page 51 and 52: INTRACARDIAC DEVICESPacemaker CodeA
Page 53 and 54: Pre-operative testing and therapy
Page 55 and 56: DYSPNEAPathophysiologyEtiologiesAir
Page 57 and 58:
Other• Behavior modification: ide
Page 59 and 60:
CHRONIC OBSTRUCTIVE PULMONARY DISEA
Page 61 and 62:
HEMOPTYSISDefinition and pathophysi
Page 63 and 64:
INTERSTITIAL LUNG DISEASEWORKUP OF
Page 65 and 66:
PLEURAL EFFUSIONPathophysiology•
Page 67 and 68:
VENOUS THROMBOEMBOLISM (VTE)Definit
Page 69 and 70:
Risk stratification for Pts with PE
Page 71 and 72:
• SupportiveOxygen: maintain S aO
Page 73 and 74:
MECHANICAL VENTILATIONIndications
Page 75 and 76:
Tailoring the ventilator settings
Page 77 and 78:
SEPSISDefinitionsSystemic2 or more
Page 79 and 80:
ESOPHAGEAL AND GASTRIC DISORDERSDYS
Page 81 and 82:
GASTROINTESTINAL BLEEDINGDefinition
Page 83 and 84:
DIARRHEA, CONSTIPATION, AND ILEUSAC
Page 85 and 86:
Dx: IgA antitissue transglutaminase
Page 87 and 88:
DIVERTICULAR DISEASEDIVERTICULOSISD
Page 89 and 90:
MANAGEMENT (Lancet 2007;369:1641 &
Page 91 and 92:
PANCREATITISPathogenesis• Acinar
Page 93 and 94:
ABNORMAL LIVER TESTSTests of hepato
Page 95 and 96:
HEPATITISVIRALHepatitis A (ssRNA; a
Page 97 and 98:
AUTOIMMUNE HEPATITIS (AIH)Classific
Page 99 and 100:
CIRRHOSISDefinition (Lancet 2008;37
Page 101 and 102:
PrognosisModified Child-Turcotte-Pu
Page 103 and 104:
HEPATIC VASCULAR DISEASEPortal vein
Page 105 and 106:
BILIARY TRACT DISEASECHOLELITHIASIS
Page 107 and 108:
ACID-BASE DISTURBANCESGENERALDefini
Page 109 and 110:
Workup for AG metabolic acidosis•
Page 111 and 112:
Etiologies of Metabolic AlkalosisSa
Page 113 and 114:
Hypovolemic hypotonic hyponatremia
Page 115 and 116:
POLYURIADefinition and pathophysiol
Page 117 and 118:
Treatment• If true potassium defi
Page 119 and 120:
Treatment• Treat underlying disor
Page 121 and 122:
DIALYSISGeneral• Substitutes for
Page 123 and 124:
Treatment• ANCA or anti-GBM: ste
Page 125 and 126:
HEMATURIAEtiologies of HematuriaExt
Page 127 and 128:
ANEMIAT in RBC mass: Hct 41% or Hb
Page 129 and 130:
MACROCYTIC ANEMIASincludes megalobl
Page 131 and 132:
• Infection: splenic infarction S
Page 133 and 134:
PLATELET DISORDERSTHROMBOCYTOPENIA
Page 135 and 136:
• Treatment of type II (NEJM 2006
Page 137 and 138:
HYPERCOAGULABLE STATESSuspect in Pt
Page 139 and 140:
TRANSFUSION THERAPYPacked red blood
Page 141 and 142:
MYELOPROLIFERATIVE NEOPLASMS (MPN)G
Page 143 and 144:
LEUKEMIAACUTE LEUKEMIADefinition•
Page 145 and 146:
Prognosis• CR achieved in 80% of
Page 147 and 148:
LYMPHOMADefinition• Malignant dis
Page 149 and 150:
Consider CNS prophylaxis w/ intrath
Page 151 and 152:
Treatment (NEJM 2004;351:1860; Lanc
Page 153 and 154:
• Sinusoidal obstruction syndrome
Page 155 and 156:
TNM Staging System for NSCLCN stage
Page 157 and 158:
Simplified Staging System for Breas
Page 159 and 160:
COLORECTAL CANCER (CRC)Epidemiology
Page 161 and 162:
PANCREATIC TUMORSPathology and gene
Page 163 and 164:
• Prostate, breast, and lung canc
Page 165 and 166:
PNEUMONIAMicrobiology of PneumoniaC
Page 167 and 168:
FUNGAL INFECTIONSCandida species•
Page 169 and 170:
URINARY TRACT INFECTIONS (UTI)Defin
Page 171 and 172:
Diagnostic studies• Superficial s
Page 173 and 174:
INFECTIONS OF THE NERVOUS SYSTEMACU
Page 175 and 176:
VIRAL ENCEPHALITISDefinition• Vir
Page 177 and 178:
Diagnostic studies• Blood culture
Page 179 and 180:
TUBERCULOSISEpidemiology• U.S.: 1
Page 181 and 182:
HIV/AIDSDefinition• AIDS: HIV CD
Page 183 and 184:
Cutaneous• Seborrheic dermatitis;
Page 185 and 186:
TICK-BORNE DISEASESDistinguishing F
Page 187 and 188:
FEVER OF UNKNOWN ORIGIN (FUO)Defini
Page 189 and 190:
PITUITARY DISORDERSHYPOPITUITARY SY
Page 191 and 192:
THYROID DISORDERSDiagnostic Studies
Page 193 and 194:
Clinical manifestations of hyperthy
Page 195 and 196:
ADRENAL DISORDERSCushing’s Syndro
Page 197 and 198:
Treatment• Adenoma or carcinoma S
Page 199 and 200:
CALCIUM DISORDERSLaboratory Finding
Page 201 and 202:
DIABETES MELLITUSDefinition (Diabet
Page 203 and 204:
Typical DKA “Flow sheet” SetupV
Page 205 and 206:
ARTHRITIS—OVERVIEWApproach to pat
Page 207 and 208:
RHEUMATOID ARTHRITIS (RA)Definition
Page 209 and 210:
CRYSTAL DEPOSITION ARTHRITIDESGOUTD
Page 211 and 212:
SERONEGATIVE SPONDYLOARTHRITISGENER
Page 213 and 214:
INFECTIOUS ARTHRITIS & BURSITISDIAG
Page 215 and 216:
CONNECTIVE TISSUE DISEASES% Autoant
Page 217 and 218:
Clinical manifestations• Muscle w
Page 219 and 220:
SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)M
Page 221 and 222:
VASCULITISLARGE-VESSEL VASCULITISTa
Page 223 and 224:
Maintenance: MTX or AZA for 2 yfor
Page 225 and 226:
CRYOGLOBULINEMIADefinition & Types
Page 227 and 228:
CHANGE IN MENTAL STATUSDefinitions
Page 229 and 230:
SEIZURESDefinitions (NEJM 2003;349:
Page 231 and 232:
ALCOHOL WITHDRAWALPathophysiology
Page 233 and 234:
Treatment of ischemic stroke (NEJM
Page 235 and 236:
MYASTHENIA GRAVISDefinition and epi
Page 237 and 238:
BACK AND SPINAL CORD DISEASEDdx of
Page 239 and 240:
ACLS ALGORITHMSFigure 10-1 ACLS VF/
Page 241 and 242:
Figure 10-3 ACLS bradycardia algori
Page 243 and 244:
DrugClassDoseper kgaverageSedationM
Page 245 and 246:
FORMULAE AND QUICK REFERENCECARDIOL
Page 247 and 248:
P KUOsmFigure 10-5 Acetaminophen to
Page 249 and 250:
Warfarin-heparin overlap therapy•
Page 251 and 252:
5-NT6-MPa/wAAAAADAbABEABGabnlABPAab
Page 253 and 254:
FRCFSGSFSHFTIFUOFVCG6PDGBGBMGBSGCAG
Page 255 and 256:
PIDPIFPIPPKDPMPMFPMHxPMIPMLPMNPMVPM
Page 257 and 258:
AA-a gradient, 2-18, 10-8abdominal
Page 259 and 260:
Ddactylitis, 8-7decerebrate posturi
Page 261 and 262:
Liddle’s syndrome, 4-5, 4-10, 7-8
Page 263 and 264:
shock, 1-13, 10-4cardiogenic, 1-13s
Page 265 and 266:
NOTES
Page 267 and 268:
RadiologyPHOTO INSERT P-11 Normal P
Page 269 and 270:
PHOTO INSERT P-37 Right middle lobe
Page 271 and 272:
13 Normal chest CT at level of pulm
Page 273 and 274:
17 Normal abdomen CT at level of li
Page 275 and 276:
EchocardiographyVentricular septumR
Page 277 and 278:
Anterolateralfree wallLeft ventricl
Page 279 and 280:
Coronary Angiography3LEFT CORONARY
Page 281:
PHOTO INSERT P-153 CML. 4 CLL.All p
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