Premenstrual Syndromes : PMS and PMDD - Rutuja :: The site ...
Premenstrual Syndromes : PMS and PMDD - Rutuja :: The site ...
Premenstrual Syndromes : PMS and PMDD - Rutuja :: The site ...
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152 THE PREMENSTRUAL SYNDROMES<br />
for a period of 2 months. Some type of severity rating<br />
must be a part of these charts, such as using a scale<br />
ranging from ‘0’ for no symptoms to ‘4’ for severe<br />
symptoms, for example, <strong>and</strong> noting those that interfere<br />
with functioning. Various validated diaries will be discussed<br />
below.<br />
<strong>The</strong> woman should then evaluate the impact of<br />
various lifestyle approaches during the recording of her<br />
symptoms. In order to minimize the her disappointment<br />
with the prospect of leaving the office without<br />
specific therapy, the following points should be made:<br />
1. <strong>The</strong> diagnosis usually requires prospective monitoring<br />
to rule out affective disorders that would<br />
require daily, not luteal, therapy with specific psychotropics,<br />
as opposed to hormonal agents.<br />
2. Treatment options will be better tailored to her<br />
symptom type <strong>and</strong> timing <strong>and</strong> to her other gynecological<br />
needs, such as treatment of dysmenorrhea<br />
or contraception.<br />
3. Lifestyle change, stress reduction, <strong>and</strong> daily charting<br />
may be effective treatment.<br />
4. Treatment is usually necessary for most of the<br />
reproductive years <strong>and</strong> thus the approach using the<br />
lowest dose of a pharmacological agent specific for<br />
the natural symptom duration <strong>and</strong> severity, <strong>and</strong><br />
providing the best side-effect profile is preferable.<br />
<strong>The</strong> second visit consists primarily of reviewing the<br />
symptom diary, establishing a diagnosis of a premenstrual<br />
disorder <strong>and</strong> choosing the optimal treatment<br />
approach. Dividing a woman’s symptom ratings into<br />
the premenstrual, menstrual, <strong>and</strong> postmenstrual phases<br />
will determine if a temporal relationship exists between<br />
symptoms <strong>and</strong> menses.<br />
Daily Rating Forms<br />
<strong>The</strong>re is a lack of agreement on the practicality of daily<br />
prospective symptom rating due to the amount of time<br />
required <strong>and</strong> delay in therapeutic interventions while<br />
symptoms are recorded. Some consider that an interview<br />
by an appropriately trained psychiatrist could<br />
suffice to exclude an underlying psychiatric disorder<br />
<strong>and</strong> could replace daily symptom recording. However,<br />
this is not universally accepted (particularly for research)<br />
<strong>and</strong> is contrary to the guidance in DSM-IV. Daily<br />
symptom diaries can also be therapeutic, increasing<br />
patient involvement <strong>and</strong> adherence to management<br />
strategies <strong>and</strong> allowing for the individualization of<br />
treatment. When the woman is unable to provide<br />
prospective data, the spouse/partner can keep a calendar<br />
of premenstrual observations to establish the type,<br />
severity, <strong>and</strong> pattern of symptoms. One must recognize<br />
the limitations of self-reported retrospective measures.<br />
Biases include sociocultural, environmental, <strong>and</strong> patient<br />
<strong>and</strong> family expectations. Patients may forget to fill out<br />
the calendar daily <strong>and</strong> use recall to complete the missed<br />
days. <strong>The</strong> use of an electronic, voice-activated device<br />
that allows the patient to record daily while blinding<br />
prior entries may assist in obtaining more accurate<br />
information. 12<br />
Some clinicians may prefer to use a visually graphic<br />
evaluative tool. A visual analog scale (VAS) requires the<br />
patient to rate specific symptoms on a line, 100 mm in<br />
length. <strong>The</strong> anchor lines at the left- <strong>and</strong> right-h<strong>and</strong> ends<br />
of the scale represent ‘0,’ or no symptoms, <strong>and</strong> ‘100,’<br />
extreme symptoms. <strong>The</strong> VAS was recently revised to<br />
more nearly reflect the DSM-IV-TR criteria for <strong>PMDD</strong>;<br />
it includes the four core symptoms (irritability, tension,<br />
depressed mood, <strong>and</strong> mood lability) <strong>and</strong> seven symptom<br />
clusters (decreased interest in usual activities, difficulty<br />
concentrating, lack of energy, appetite change, change<br />
in sleep, feeling out of control, <strong>and</strong> somatic symptoms). 1<br />
<strong>The</strong> days most appropriate for calculating the follicular<br />
<strong>and</strong> luteal score in a clinical setting are cycle days 7<br />
through 11 for the follicular score <strong>and</strong> days 16 through<br />
22 for the late luteal score. 13<br />
<strong>The</strong> Calendar of <strong>Premenstrual</strong> Experiences (COPE)<br />
is a daily diary that includes 22 symptoms commonly<br />
reported by women with <strong>PMS</strong>. 14 <strong>The</strong> symptoms are<br />
rated on a four-point scale, ranging from ‘0’ for no<br />
symptoms to ‘3,’ which indicates that the symptoms are<br />
severe <strong>and</strong> the woman is unable to perform normal<br />
activities. <strong>PMS</strong> is diagnosed when the total of the<br />
points for the luteal phase (i.e. the last 7 days of the<br />
cycle) is at least 30% greater than the sum of points for<br />
the follicular phase of the cycle (i.e. days 3 through 9 of<br />
the cycle).<br />
<strong>The</strong> Daily Record of Severity of Problems (DRSP) is<br />
a daily diary that has been developed for use in the<br />
diagnosis of <strong>PMDD</strong>. 15 <strong>The</strong> 11 symptoms included in<br />
the DSM-IV-TR diagnostic criteria for <strong>PMDD</strong> are<br />
described in 21 separate items. In addition, the DRSP<br />
includes three symptom-related areas of functional<br />
impairment that are necessary for the diagnosis of<br />
<strong>PMDD</strong>. Women are also instructed to list the days of<br />
bleeding. Symptoms are rated on a scale ranging from<br />
1 � not at all to 6 � extreme. <strong>The</strong> individual <strong>and</strong><br />
summary scores in the DRSP have high reliability <strong>and</strong><br />
tend to be sensitive to treatment differences.<br />
Severe <strong>PMS</strong> <strong>and</strong> <strong>PMDD</strong> can be difficult to differentiate<br />
from the premenstrual exacerbation of a medical or<br />
psychiatric disorder. At present, a diagnosis of <strong>PMDD</strong><br />
specifically requires the exclusion of any psychiatric<br />
disorder that might explain the symptoms. 5 In screening<br />
for psychiatric disorders, it is especially important<br />
to determine any past or current episodes of depressive,