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Premenstrual Syndromes : PMS and PMDD - Rutuja :: The site ...

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152 THE PREMENSTRUAL SYNDROMES<br />

for a period of 2 months. Some type of severity rating<br />

must be a part of these charts, such as using a scale<br />

ranging from ‘0’ for no symptoms to ‘4’ for severe<br />

symptoms, for example, <strong>and</strong> noting those that interfere<br />

with functioning. Various validated diaries will be discussed<br />

below.<br />

<strong>The</strong> woman should then evaluate the impact of<br />

various lifestyle approaches during the recording of her<br />

symptoms. In order to minimize the her disappointment<br />

with the prospect of leaving the office without<br />

specific therapy, the following points should be made:<br />

1. <strong>The</strong> diagnosis usually requires prospective monitoring<br />

to rule out affective disorders that would<br />

require daily, not luteal, therapy with specific psychotropics,<br />

as opposed to hormonal agents.<br />

2. Treatment options will be better tailored to her<br />

symptom type <strong>and</strong> timing <strong>and</strong> to her other gynecological<br />

needs, such as treatment of dysmenorrhea<br />

or contraception.<br />

3. Lifestyle change, stress reduction, <strong>and</strong> daily charting<br />

may be effective treatment.<br />

4. Treatment is usually necessary for most of the<br />

reproductive years <strong>and</strong> thus the approach using the<br />

lowest dose of a pharmacological agent specific for<br />

the natural symptom duration <strong>and</strong> severity, <strong>and</strong><br />

providing the best side-effect profile is preferable.<br />

<strong>The</strong> second visit consists primarily of reviewing the<br />

symptom diary, establishing a diagnosis of a premenstrual<br />

disorder <strong>and</strong> choosing the optimal treatment<br />

approach. Dividing a woman’s symptom ratings into<br />

the premenstrual, menstrual, <strong>and</strong> postmenstrual phases<br />

will determine if a temporal relationship exists between<br />

symptoms <strong>and</strong> menses.<br />

Daily Rating Forms<br />

<strong>The</strong>re is a lack of agreement on the practicality of daily<br />

prospective symptom rating due to the amount of time<br />

required <strong>and</strong> delay in therapeutic interventions while<br />

symptoms are recorded. Some consider that an interview<br />

by an appropriately trained psychiatrist could<br />

suffice to exclude an underlying psychiatric disorder<br />

<strong>and</strong> could replace daily symptom recording. However,<br />

this is not universally accepted (particularly for research)<br />

<strong>and</strong> is contrary to the guidance in DSM-IV. Daily<br />

symptom diaries can also be therapeutic, increasing<br />

patient involvement <strong>and</strong> adherence to management<br />

strategies <strong>and</strong> allowing for the individualization of<br />

treatment. When the woman is unable to provide<br />

prospective data, the spouse/partner can keep a calendar<br />

of premenstrual observations to establish the type,<br />

severity, <strong>and</strong> pattern of symptoms. One must recognize<br />

the limitations of self-reported retrospective measures.<br />

Biases include sociocultural, environmental, <strong>and</strong> patient<br />

<strong>and</strong> family expectations. Patients may forget to fill out<br />

the calendar daily <strong>and</strong> use recall to complete the missed<br />

days. <strong>The</strong> use of an electronic, voice-activated device<br />

that allows the patient to record daily while blinding<br />

prior entries may assist in obtaining more accurate<br />

information. 12<br />

Some clinicians may prefer to use a visually graphic<br />

evaluative tool. A visual analog scale (VAS) requires the<br />

patient to rate specific symptoms on a line, 100 mm in<br />

length. <strong>The</strong> anchor lines at the left- <strong>and</strong> right-h<strong>and</strong> ends<br />

of the scale represent ‘0,’ or no symptoms, <strong>and</strong> ‘100,’<br />

extreme symptoms. <strong>The</strong> VAS was recently revised to<br />

more nearly reflect the DSM-IV-TR criteria for <strong>PMDD</strong>;<br />

it includes the four core symptoms (irritability, tension,<br />

depressed mood, <strong>and</strong> mood lability) <strong>and</strong> seven symptom<br />

clusters (decreased interest in usual activities, difficulty<br />

concentrating, lack of energy, appetite change, change<br />

in sleep, feeling out of control, <strong>and</strong> somatic symptoms). 1<br />

<strong>The</strong> days most appropriate for calculating the follicular<br />

<strong>and</strong> luteal score in a clinical setting are cycle days 7<br />

through 11 for the follicular score <strong>and</strong> days 16 through<br />

22 for the late luteal score. 13<br />

<strong>The</strong> Calendar of <strong>Premenstrual</strong> Experiences (COPE)<br />

is a daily diary that includes 22 symptoms commonly<br />

reported by women with <strong>PMS</strong>. 14 <strong>The</strong> symptoms are<br />

rated on a four-point scale, ranging from ‘0’ for no<br />

symptoms to ‘3,’ which indicates that the symptoms are<br />

severe <strong>and</strong> the woman is unable to perform normal<br />

activities. <strong>PMS</strong> is diagnosed when the total of the<br />

points for the luteal phase (i.e. the last 7 days of the<br />

cycle) is at least 30% greater than the sum of points for<br />

the follicular phase of the cycle (i.e. days 3 through 9 of<br />

the cycle).<br />

<strong>The</strong> Daily Record of Severity of Problems (DRSP) is<br />

a daily diary that has been developed for use in the<br />

diagnosis of <strong>PMDD</strong>. 15 <strong>The</strong> 11 symptoms included in<br />

the DSM-IV-TR diagnostic criteria for <strong>PMDD</strong> are<br />

described in 21 separate items. In addition, the DRSP<br />

includes three symptom-related areas of functional<br />

impairment that are necessary for the diagnosis of<br />

<strong>PMDD</strong>. Women are also instructed to list the days of<br />

bleeding. Symptoms are rated on a scale ranging from<br />

1 � not at all to 6 � extreme. <strong>The</strong> individual <strong>and</strong><br />

summary scores in the DRSP have high reliability <strong>and</strong><br />

tend to be sensitive to treatment differences.<br />

Severe <strong>PMS</strong> <strong>and</strong> <strong>PMDD</strong> can be difficult to differentiate<br />

from the premenstrual exacerbation of a medical or<br />

psychiatric disorder. At present, a diagnosis of <strong>PMDD</strong><br />

specifically requires the exclusion of any psychiatric<br />

disorder that might explain the symptoms. 5 In screening<br />

for psychiatric disorders, it is especially important<br />

to determine any past or current episodes of depressive,

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