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Acute Aortic Disease.. - Index of

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126 Elefteriades and Koullias<br />

Figure 1 (See color insert) The technique <strong>of</strong> epi-aortic echocardiography. Note the fluidfilled<br />

interface between the probe and the aortic wall.<br />

1. The diameter <strong>of</strong> the aorta, in systole and diastole.<br />

2. The thickness <strong>of</strong> the aortic wall, in systole and diastole. (The aortic<br />

wall thins in systole, under the increased stretch <strong>of</strong> the higher pressure.<br />

This measurement <strong>of</strong> subtle differences in a small dimension has a<br />

significant learning curve attached to it.)<br />

3. The blood pressure, in systole and diastole. (In our experiments, the<br />

blood pressure was determined very accurately using intraoperative<br />

direct arterial line monitoring.)<br />

What we found was that the distensibility <strong>of</strong> the aorta essentially vanishes<br />

as the dimension <strong>of</strong> the aorta increased (Fig. 3). The normally distensible aorta<br />

became essentially a rigid tube at about 6 cm in diameter.<br />

Likewise, wall stress shows dramatic and serious aberrations as the aorta<br />

grows, again reaching critical levels by about 6 cm aortic diameter (Fig. 4). The<br />

maximal strength <strong>of</strong> the aortic wall is known by prior investigations done directly<br />

Mechanical Properties <strong>of</strong> the Aneurysmal<br />

Human Ascending Aorta<br />

d<br />

BP<br />

t<br />

All mechanical characteristics<br />

can be calculated on the basis <strong>of</strong><br />

six parameters:<br />

d<br />

t<br />

BP<br />

systole<br />

diastole<br />

Figure 2 The parameters that need to be measured for calculation <strong>of</strong> mechanical properties<br />

<strong>of</strong> the aorta.

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