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Acute Aortic Disease.. - Index of

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192 Coady and Elefteriades<br />

another cause—angina, esophageal spasm, lumbosacral spine disease or the<br />

like—we presume that the pain is <strong>of</strong> aortic origin. We know <strong>of</strong> no other way to<br />

protect the patient from aortic rupture than to draw this conclusion.<br />

It is taken as self-evident that age and coexisting disease may well render<br />

aggressive surgical intervention inappropriate for some patients. Thus, each patient<br />

must be evaluated independently, and anticipated risks <strong>of</strong> operation (especially<br />

paraplegia with descending aortic aneurysms) weighed against the anticipated<br />

risks <strong>of</strong> rupture and dissection. Moreover, the level <strong>of</strong> experience at the treating<br />

medical center with these major surgical procedures must be taken into account.<br />

The size criteria presented in this chapter are proposed for otherwise healthy<br />

patients cared for at experienced centers.<br />

CONCLUSION<br />

The natural behavior <strong>of</strong> the thoracic aorta is increasingly being clarified, strengthening<br />

the physician’s and surgeon’s position in the treatment <strong>of</strong> patients harboring<br />

this virulent disease.<br />

REFERENCES<br />

1. Majumber PP, St Jean PL, Ferrell RE, et al. On the inheritance <strong>of</strong> abdominal aortic<br />

aneurysm. Am J Hum Genet 1991; 48:164–170.<br />

2. Bickerstaff LK, Palrolero PC, Hollier LH, et al. Thoracic aortic aneurysms: a population<br />

based study. Surgery 1982; 92(6):1103–1108.<br />

3. LaRoy LL, Cormier PJ, Matalon TA, Patel SK, Turner DA, Silver B. Imaging <strong>of</strong><br />

abdominal aortic aneurysms. AJR Am J Roentgenol 1989; 152(4):785–792.<br />

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follow-up for 520 patients treated surgically. Surgery 1982; 92:1118–1134.<br />

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pathology and surgical technique. Baltimore: Williams and Walters, 1984.<br />

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annulo-aortic ectasia. J Thoracic Cardiovasc Surg 1961; 42:363–370.<br />

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novo missense mutation in the fibrillin gene. Nature 1991; 352(6333):337–339.<br />

11. Coady MA, Davies RR, Roberts M, et al. Familial patterns <strong>of</strong> thoracic aortic aneurysms.<br />

Arch Surg 1999; 134:361–367.<br />

12. Albornoz G, Coady MA, Roberts M, Davies RR, Rizzo JA, Elefteriades JA. Familial<br />

thoracic aortic aneurysms and dissections—incidence, modes <strong>of</strong> inheritance, and<br />

phenotypic patterns. Ann Thorac Surg 2006; 82(4):1400–1405.<br />

13. Sumner DS, Hokanson DE, Strandness DE Jr. Stress-strain characteristics and collagen-elastin<br />

content <strong>of</strong> abdominal aortic aneurysms. Surg Gynecol Obstet 1970;<br />

130(3):459–466.

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