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Acute Aortic Disease.. - Index of

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Natural History <strong>of</strong> Thoracic <strong>Aortic</strong> Aneurysms 195<br />

DISCUSSION AND COMMENTARY<br />

Questions for the Authors<br />

How <strong>of</strong>ten should the aorta be imaged in a patient in follow-up for a thoracic<br />

aortic aneurysm?<br />

We tend to image rather infrequently, as the aneurysmal thoracic aorta grows<br />

slowly—at just over 1 mm (0.1 cm) per year. So, because <strong>of</strong> this indolent growth,<br />

frequent scans will not show any changes—just like a parent does not notice the<br />

growth <strong>of</strong> his children, whom he sees every day.<br />

What is most important is to compare your current study, not with the last<br />

prior study, but with the earliest study on record for your patient. This is how<br />

growth can be appropriately noted and appreciated. This takes more work and<br />

may mean digging deep into a computerized registry <strong>of</strong> CT scans or pulling old<br />

hard copies <strong>of</strong> imaging studies. We recently published a plea to radiologists to do<br />

this extra work <strong>of</strong> comparing with the earliest study on record, to prevent missing<br />

substantive overall growth by comparing only with the most recent study (1).<br />

When seeing a patient for the first time, we usually re-image in 6 to<br />

12 months, so as to identify a quick second point on the size or growth curve for<br />

that patient. Thereafter, it is rare for us to image more frequently than every one<br />

to two years. We must be cognizant also <strong>of</strong> the radiation danger <strong>of</strong> CT scanning.<br />

Does the aorta ever grow very rapidly?<br />

With rare exceptions, sudden, rapid growth <strong>of</strong> the aorta is usually spurious, involving<br />

measurement at noncorresponding segments <strong>of</strong> the aorta on different scans.<br />

Another common source <strong>of</strong> error has to do with measuring across oblique segments<br />

<strong>of</strong> the aorta (such as the aortic arch on an axial study); obliquity will give<br />

an oblong cross-section, which overestimates true diameter.<br />

A sudden true increase in caliber <strong>of</strong> the thoracic aorta can be caused by<br />

intercurrent aortic dissection. If the aorta has truly grown, please be sure to<br />

check for presence <strong>of</strong> a dissection flap, which may have developed in the interim<br />

between studies.<br />

What imaging study should I use in follow-up?<br />

Our studies have shown a high concordance between dimensions on echocardiography,<br />

CT scanning, and MRI imaging. For acutely ill patients, we usually prefer<br />

ECHO and CT, which are immediately available. For chronic follow-up, we<br />

usually prefer ECHO for young patients, especially women <strong>of</strong> childbearing age.<br />

Of course, the (transthoracic) ECHO shows mainly the proximal ascending aorta,<br />

so for older patients, we combine with either CT or MRI, which shows very well the<br />

entirely <strong>of</strong> the aorta—ascending, arch, descending, and abdominal.<br />

How about family members?<br />

There is no longer any question that thoracic aortic aneurysm is a hereditary disease,<br />

and abdominal aneurysm as well. We recommend imaging all first-order

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