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Male Infertility A child of my own - Andrology Australia

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APPENDICESABSENCE OF VAS DEFERENSfluid in the ejaculate, so absence <strong>of</strong> the seminalvesicles can cause a smaller amount <strong>of</strong> ejaculate(usually about 0.5 ml, compared with a normalman <strong>of</strong> more than 2 ml). The seminal vesicles alsomake the ejaculate alkaline, so when they are notthere the ejaculate is more acidic.How is absence <strong>of</strong> the vas deferens andseminal vesicles treated?At this stage there are no surgical treatments thatwill cure CAVD. ICSI is usually needed if menwish to have a family. When the vas deferens andseminal vesicles are missing, it is usually possible tocollect sperm directly from the testis or from thesmall remaining part <strong>of</strong> the epididymis.[See section: ‘Having a Family’ for more information]What are other considerations for menwith CAVD?Due to the genetic basis <strong>of</strong> this problem, boththe man and his partner must have a blood testto check for changes in the CFTR gene, beforestarting assisted reproduction treatments. If bothpartners have CFTR mutations, then there is aone in four chance <strong>of</strong> severe cystic fibrosis in their<strong>child</strong>ren. It may be possible to test the fertilisedeggs, using a technique kn<strong>own</strong> as pre-implantationgenetic diagnosis (PGD). Only the embryos thatare not affected by the CFTR mutations aretransferred to the woman’s uterus.MALE INFERTILITY 88

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