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06.qxd 3/10/08 9:34 AM Page 217<br />

Hyperactivity<br />

Hyperactivity, which might just as well be termed pressure<br />

of activity, follows from the patients’ grandiosity and<br />

increased energy. Patients may enter into business arrangements<br />

with unbounded and completely uncritical enthusiasm.<br />

Ventures are begun, stocks are bought on a hunch,<br />

money is loaned out without collateral, and when the family<br />

fortune is spent, manic patients, undaunted, may seek<br />

to borrow more money for yet another prospect. Spending<br />

sprees are also quite typical. Clothes, furniture, and cars<br />

may be bought; the credit card is pushed to the limit, and<br />

another one is obtained; checks, without any foundation in<br />

the bank account, are written with alacrity. Kraepelin<br />

noted that such a patient is swelled by a ‘need to get out of<br />

himself, to be on more intimate terms with his surroundings,<br />

to play a part’. It causes him:<br />

to change about his furniture, to visit distant<br />

acquaintances, to take himself up with all possible<br />

things and circumstances, which formerly he never<br />

thought about. Politics, the universal language,<br />

aeronautics, the women’s question, public affairs of<br />

all kinds and their need of improvement, give him<br />

employment. A physician advertised about ‘original<br />

sin, Genesis, natural selection and breeding’. Another<br />

patient drove about in a cab and distributed pictures<br />

of the saints. The patient enters into numerous<br />

engagements, suddenly pays all his business debts<br />

without it being necessary, makes magnificent<br />

presents, builds all kinds of castles in the air, and<br />

with swift enthusiasm precipitates himself in daring<br />

undertakings much beyond his powers. He has 16,000<br />

picture post-cards of his little village printed. . . .<br />

STAGE II MANIA: ACUTE MANIA<br />

Kraepelin (1921)<br />

The transition from hypomania to acute mania is marked by<br />

a severe exacerbation of the symptoms seen in hypomania<br />

and by the appearance of delusions, typically delusions of<br />

grandeur. Kraepelin noted, ‘The patient asserts that he is<br />

descended from a noble family, that he is a gentleman; he<br />

calls himself a genius, the Emperor William, the Emperor of<br />

Russia, Christ; he can drive out the devil. A patient suddenly<br />

cried out on the street that he was the Lord God . . . ’.<br />

Delusions of persecution may also occur, especially in<br />

patients with irritability. Patients may assert that their failures<br />

are not their own but the result of treacheries and<br />

betrayals by family members or business colleagues. They<br />

are persecuted by those jealous of their grandeur; they are<br />

pilloried and crucified by their enemies. Terrorists have set a<br />

watch on their houses and seek to destroy them before they<br />

can ascend their thrones. Occasionally, in addition to these<br />

delusions, there may be transitory hallucinations. Grandiose<br />

patients may hear a chorus of angels; persecuted patients<br />

may hear the resentful muttering of the envious crowd.<br />

6.3 Mania 217<br />

With the intensification of hypomanic symptoms and<br />

the appearance of delusions, the overall behavior of these<br />

patients may become quite extravagant. Kraepelin noted<br />

that patients may:<br />

run out of the house in a shirt, go to church in a<br />

petticoat, spend the night in a field of corn, give away<br />

their property, disturb the service in church by<br />

screaming and singing, kneel and pray on the street,<br />

fire a pistol in the waiting-room, put soap and soda in<br />

the food, try to force their way into the palace, throw<br />

objects out at the window. A female patient jumped<br />

into the carriage of a prince for a joke . . . A male<br />

patient appropriated the property of others in taverns.<br />

Another appeared in the court of justice in order to<br />

catch a murderer.<br />

STAGE III MANIA: DELIRIOUS MANIA<br />

Kraepelin (1921)<br />

The transition to delirious mania is marked by the appearance<br />

of confusion, more hallucinations, and an intense<br />

exacerbation of all the symptoms seen in stage II. There<br />

may be a dream-like clouding of consciousness and<br />

patients may become unaware of where they are; incoherence<br />

may appear and, as described by Kraepelin, ‘Their linguistic<br />

utterances alternate between inarticulate sounds,<br />

praying, abusing, entreating, stammering, disconnected<br />

talk, in which clang-associations, senseless rhyming, diversion<br />

by external impressions, persistence of individual<br />

phrases, are recognized’. Hallucinations become prominent,<br />

and as further described by Kraepelin, ‘The patient<br />

sees heaven open, full of camels and elephants, the King,<br />

his guardian-angel, the Holy Ghost; the devil has assumed<br />

the form of the Virgin Mary. The ringing of bells is heard,<br />

shooting, the rushing of water, a confused noise; Lucifer is<br />

speaking; the voice of God announces to him the day of<br />

judgment, redemption from all sins’.<br />

With this evolution into stage III, overall behavior<br />

becomes very fragmented, and patients may ‘become stupefied,<br />

confused, bewildered’, they may:<br />

dance about, perform peculiar movements, shake<br />

their head, throw the bedclothes pell-mell, are<br />

destructive, pass their movements under them, smear<br />

everything, make impulsive attempts at suicide, take<br />

off their clothes. A patient was found completely<br />

naked in a public park. Another ran half-clothed into<br />

the corridor and then into the street, in one hand a<br />

revolver in the other a crucifix.<br />

Etiology<br />

Kraepelin (1921)<br />

The various causes of mania are listed in Table 6.4, in which<br />

they are organized into several groups. The first group is

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