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x.qxd 3/10/08 10:01 AM Page 719<br />

mania 219<br />

psychosis 240<br />

in parkinsonism 91<br />

response aiding differential diagnosis<br />

348<br />

in Parkinson’s disease 348, 349<br />

restless legs syndrome 582<br />

levodopa-responsive dystonia 365<br />

Lewy body<br />

diffuse Lewy body disease 351<br />

Parkinson’s disease 346, 347<br />

Lewy body disease, diffuse 350–2<br />

clinical features 351<br />

dementia 163, 168, 351<br />

depression 212, 351, 352<br />

parkinsonism 88–9, 350, 351, 352<br />

course 351<br />

differential diagnosis 351–2<br />

Alzheimer’s disease 339<br />

Binswanger’s disease 437<br />

frontotemporal dementia 342<br />

Parkinson’s disease 347, 352<br />

progressive supranuclear palsy 353<br />

etiology 351<br />

treatment 352<br />

light touch, assessment 12<br />

Lilliputian hallucinations 142<br />

limb(s)<br />

pain see pain<br />

periodic movements in sleep 582–3<br />

phantom and supernumerary 131–2<br />

see also restless legs syndrome<br />

limbic encephalitis 553–5<br />

clinical features 553–4<br />

amnesia 186<br />

delirium 181<br />

depression 213<br />

personality change 246<br />

course 554<br />

differential diagnosis 554–5<br />

etiology 554<br />

treatment 555<br />

line bisection test 63<br />

line cancellation test 63<br />

lipofuscinosis, neuronal ceroid, adult form<br />

(Kufs’ disease) 172, 377<br />

lipohyalinosis 284<br />

lithium<br />

intoxication 170<br />

therapeutic use 622, 623<br />

litigious delusions 616<br />

liver disorders/disease<br />

parkinsonism in 90<br />

in Wilson’s disease 361<br />

see also encephalopathy; hepatocerebral<br />

degeneration; porphyria, hepatic<br />

locked-in syndrome vs mutism 119<br />

long-term memory, testing 9–10<br />

lorazepam<br />

alcohol withdrawal 665<br />

seizures 666<br />

traumatic brain injury 289<br />

Lorenzo’s oil 377<br />

low-flow infarctions see watershed<br />

infarctions<br />

lumbar puncture 31–3, 33–4<br />

complications 32–3<br />

contraindications 32<br />

indications 32<br />

brain tumors 597<br />

technique 32<br />

see also cerebrospinal fluid tests<br />

lupus, drug-induced, vs SLE 550<br />

lupus erythematosus, systemic see systemic<br />

lupus erythematosus<br />

lying (simple) vs confabulation 136<br />

Lyme disease (Lyme borreliosis) 510–11<br />

clinical features 510–11<br />

dementia 166, 511<br />

lymphoma, CNS, primary 598<br />

McLeod syndrome vs<br />

choreoacanthocytosis 358<br />

macrocytosis in vitamin B12 deficiency<br />

466<br />

magnetic resonance imaging 17–18<br />

alcoholism<br />

dementia 692<br />

Marchiafava–Bignami disease 694–5<br />

autism 417<br />

Binswanger’s disease 19–20, 436<br />

cerebral amyloid angiopathy 438<br />

clinical indications (in general) 18–21<br />

developmental dysphasia 421<br />

fat embolism syndrome 446<br />

fragile X syndrome 410<br />

hepatic porphyria 483<br />

hepatocerebral degeneration (acquired)<br />

483<br />

hydrocephalus 601<br />

normal-pressure 603<br />

hypertensive encephalopathy 444<br />

immune-related disorders<br />

Hashimoto’s encephalopathy 557<br />

limbic encephalitis 554<br />

multiple sclerosis 20, 545<br />

sarcoidosis 556<br />

Susac’s syndrome 553<br />

Sydenham’s chorea 559<br />

systemic lupus erythematosus 549<br />

infectious and post-infectious disorders<br />

acute disseminated encephalomyelitis<br />

504–5<br />

arboviral meningoencephalitis 497<br />

CMV encephalitis 495<br />

HIV disease/AIDS 20, 494<br />

HSV encephalitis 20, 498, 499<br />

Lyme disease 511<br />

progressive multifocal<br />

leukoencephalopathy 496<br />

subacute sclerosing panencephalitis<br />

506<br />

toxoplasmosis 515<br />

Whipple’s disease 513<br />

Index 719<br />

inhalent-induced dementia 695<br />

MELAS 445<br />

multi-infarct dementia 433<br />

neurodegenerative and movement<br />

disorders<br />

adrenoleukodystrophy 376<br />

Alzheimer’s disease 336<br />

amyotrophic lateral sclerosis 343<br />

cerebrotendinous xanthomatosis<br />

373<br />

dentatorubropallidoluysian atrophy<br />

360<br />

diffuse Lewy body disease 351<br />

fragile X-associated tremor/ataxia<br />

syndrome 359<br />

Huntington’s disease 356<br />

multiple system atrophy 355<br />

Pick’s disease 340<br />

progressive supranuclear palsy<br />

353<br />

spinocerebellar ataxia 363<br />

Wilson’s disease 361<br />

post-anoxic encephalopathy 462–3<br />

prion diseases<br />

Creutzveldt–Jakob disease 525<br />

new-variant Creutzveldt–Jakob<br />

disease 527<br />

reversible posterior<br />

leukoencephalopathy 444<br />

seizures 269<br />

Sjögren’s syndrome 551<br />

stroke 285<br />

trauma<br />

dementia pugilistica 456<br />

diffuse axonal injury 456<br />

subdural hematoma 454<br />

tuberous sclerosis 405<br />

tumors 20, 21, 597<br />

vitamin B12 deficiency 466<br />

von Recklinghausen’s disease 406<br />

Wernicke’s encephalopathy 470<br />

malaria 514–15<br />

malignancy (cancer), pancreatic,<br />

depression 211<br />

malignant hyperthermia vs neuroleptic<br />

malignant syndrome 684<br />

malingering 302<br />

differential diagnosis<br />

Briquet’s syndrome 300<br />

conversion disorder 299<br />

hypochondriasis 301<br />

post-traumatic stress disorder 641<br />

psychosis 243<br />

hypoglycemia intentionally produced<br />

478<br />

mutism 118<br />

manganese intoxication 472–3<br />

clinical features 472<br />

dementia 168, 472<br />

parkinsonism 90, 168, 472, 473<br />

personality change 246, 472, 473<br />

psychosis 240–1, 472

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