Protocolo-TEA-final

VABS CommunicationDomainVineland AdaptiveBehaviorScalesFollow-up: 1-3 yearsThe mean VABScommunicationdomain in thecontrol groups was0.05 standarddeviationunits lower at posttreatmentcomparedto pretreatment(0.43 lower to0.34 higher)1,7The mean VABScommunicationdomain in theinterventiongroups was0.74 standard deviationshigher (0.3 to 1.18higher)2171(5 studies 8 )⊕⊕low4,5SMD 0.74 (0.3 to 1.18)*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk inthe comparison group and the relative effect of the intervention (and its 95% CI).CI: Confidence intervalGRADE Working Group grades of evidenceHigh quality: Further research is very unlikely to change our confidence in the estimate of effect.Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.Very low quality: We are very uncertain about the estimate1 This is a difference in standard deviations calculated for the TAU group from change scores before and after the intervention period.2 This is a difference between standard deviations3 CCT (Cohen 2006, Howard 2005, Magiati 2007) and 1 RCT111