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Evaluation of the efficacy of a dietary supplement containing polyunsaturated fatty acids (PUFAs) and vitamins in the management of dermatitis r eferences 1. Tsoureli-Nikita E, Hercogova J, Lotti T, et al. Evaluation of dietary intake of vitamin E in the treatment of atopic dermatitis: a study of the clinical corse and evaluation of the immunoglobulin E serum levels. Int J Dermatol 2002; 41:146-50. 2. Yen Ch, Dai YS, Yang YH, et al. Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis. Ann Allergy Asthma Immunol 2008; 100:66-73. 2. Rodriguez-Cruz M, Tovar AR, del Prado M, et al. Molecular mechanisms of action and health benefits of polyunsaturated fatty acid. Rev Invest Clin 2005; 57:457- 472. 4. Calder PC. Abnormal fatty acid profiles occur in atopic dermatitis but what do they mean? Clin Exp Allergy 2006; 36:138-141. 5. Kitz R, Rose MA, Schönborn H, et al. Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy. Pediatr Allergy Immunol 2006; 17:112-7. 6. Horrobin DF. Essential fatty acid metabolism and its modification in atopic eczema. Am J Clin Nutr 2000; 71(Suppl 1):367S-72S. 7. Burton GW, Joyce A, Ingold KU. First proof that vitamin E is major lipid-soluble, chain-breaking antioxidant in human blood plasma. Lancet 1982; 7:327. 8. Fogarty A, Lewis S, Weiss S, et al. Dietary vitamin E, IgE concentration and atopy. Lancet 2000; 356:1573. Journal of Plastic Dermatology 2010; 6, 2 125
Gianluca Campiglio External laser lipolisys in the treatment of cellulite: preliminary data Gianluca Campiglio Summary External laser lipolisys in the treatment of cellulite: preliminary data Board Certified Plastic Surgeon Milan, Italy In this paper the preliminary data from the first Italian experience with the use of a new device for the treatment of cellulite are reported. The machine is based on a innovative technology which couples the lipolytic effects of a dual wavelength laser with a suction assisted mechanical massage. A total of 11 patients have been enrolled in the study and concluded a cycle of treatments consisting in two sessions per week for a period of 4 weeks. Each patient filled in a satisfaction survey and was documented with digital photos before and after the treatment. The results showed a very high satisfaction rate, already after the first sessions, and also the comparison of the photos evidenced an improvement in the skin contour. These preliminary data confirm previous reports on the efficacy of the device but must be completed with further investigations using wider samples of patient, more reproducible protocols of treatment and more objective methods of evaluation of the results. KEY WORDS: Cellulite, Laser, Treatment I ntroduction Fat accumulation is an esthetic problem very often complained by the women. It is well demonstrated that this tissue can be accumulated in the human body in deep and superficial fat layers (Figure 1). Deep depots, such as flanks, thighs, abdomen and knees are located immediately above the muscular fascia and below the superficial fascia which is a structure present in almost all the human body under the subcutaneous fat. For these depots the ideal treatment is suctioned assisted lipectomy which allows to remove them in a very precise and definitive way. Modern liposuction is performed with fine cannulas (diameter 2-3 mm) to reduce the rate of dimples or skin irregularities and using local anesthesia which has been demonstrated to significantly decrease the risk of major complications such as thromboembolism (Figure 2). Cellulite is a very common disease of the superficial fat layer which is immediately located under the dermis. It is characterized by engor- ged fat cells trapped in a fibrotic network of fibrous septae located in the hypodermis. According to Curri 1 cellulite can be clinically staged in four grades which are: Grade 1 = oedema, Grade 2 = fibrosis, Grade 3 = fibrosis Figure 1. Anatomic preparation showing the two different fat layers in the abdominal wall. Journal of Plastic Dermatology 2010; 6, 2 127
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