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Dichter bij diabetes - Bvvde

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Inhoud:<br />

Deel 1: Wat is <strong>diabetes</strong> mellitus? ......................................................................................................7<br />

1. Over <strong>diabetes</strong> mellitus...............................................................................................................7<br />

1.1 Inleiding ...............................................................................................................................7<br />

1.2 Rol van de alvleesklier .........................................................................................................7<br />

1.3 Type-1-<strong>diabetes</strong>...................................................................................................................9<br />

1.4 Type-2-<strong>diabetes</strong>...................................................................................................................9<br />

1.5 Type-3-<strong>diabetes</strong>...................................................................................................................9<br />

1.6 Zwangerschaps<strong>diabetes</strong> •..................................................................................................10<br />

1.7 Pre<strong>diabetes</strong>........................................................................................................................10<br />

2. Het metabool syndroom ..........................................................................................................12<br />

2.1 Inleiding .............................................................................................................................12<br />

2.2 Historisch perspectief.........................................................................................................12<br />

2.3 Definitie..............................................................................................................................14<br />

2.4 Pathogenese......................................................................................................................14<br />

3. OntregeIde <strong>diabetes</strong> en hijperglijkemie ...................................................................................18<br />

3.1 Inleiding .............................................................................................................................18<br />

3.2 Diabetische ketoacidose ....................................................................................................19<br />

3-3 Hyperosmolair hyperglykemisch non-ketotisch syndroom.................................................19<br />

3.4 Behandeling van hyperglykemische ontregeling................................................................20<br />

4. Hypoglykemie..........................................................................................................................22<br />

4.1 Inleiding .............................................................................................................................22<br />

4.2 Definitie..............................................................................................................................22<br />

4.3 Prevalentie.........................................................................................................................23<br />

4.4 Klinisch beeld.....................................................................................................................23<br />

4.5. Lichaamseigen tegenregulatie ..........................................................................................24<br />

4.6 Oorzaken van hypoglykemie..............................................................................................25<br />

4.7 Hypoglykemie en orale bloedglucoseverlagende middelen ...............................................25<br />

4.8 Hypoglykemie en insulinetherapie .....................................................................................26<br />

4.9 Hypoglykemie corrigeren ...................................................................................................27<br />

4.10 Analyse ............................................................................................................................29<br />

4.11 Preventie.......................................................................................................................30<br />

5. Complicaties............................................................................................................................30<br />

5.1 Inleiding .............................................................................................................................30<br />

5.2 Macrovasculaire complicaties ............................................................................................30<br />

5.3 Diabetische voet ................................................................................................................31<br />

5.4 Microvasculaire complicaties .............................................................................................35<br />

5.5 Diabetische nefropathie .....................................................................................................35<br />

5.6 Diabetische retinopathie ....................................................................................................38<br />

5.7 Diabetische neuropathie ....................................................................................................43<br />

6. Psychologische aspecten........................................................................................................44<br />

6.1 Inleiding .............................................................................................................................44<br />

6.2 Angststoornissen ...............................................................................................................45<br />

6.3 . Depressie.........................................................................................................................46<br />

6.4 Eetstoornissen ...................................................................................................................46<br />

6.5 Cognitief disfunctioneren ...................................................................................................47<br />

6.6 Psychologische expertise voor het eerstelijns <strong>diabetes</strong>team .............................................47<br />

Deel 2: Behandeling van <strong>diabetes</strong> mellitus .....................................................................................48<br />

7. Opsporing en diagnose ..........................................................................................................48<br />

7.1 Inleiding .............................................................................................................................48<br />

7.2 Epidemiologie ....................................................................................................................48

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