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Continuous Improvement and the Expansion of Quality ... - NCQA

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C H R o N I C D I S E A S E M A N A G E M E N T<br />

64<br />

N AT I o N A l C o M M I T T E E f o R Q U A l I T y A S S U R A N C E<br />

PHARMACoTHERAPy MANAGEMENT<br />

<strong>of</strong> CoPD ExACERbATIoN<br />

Chronic obstructive pulmonary disease (CoPD) exacerbations are characterized by acute<br />

worsening <strong>of</strong> clinical symptoms (e.g., breathlessness or sputum production). Exacerbations<br />

may range from temporary decline in functional status to fatal events. 1,2 After an exacerbation,<br />

patients’ symptoms <strong>and</strong> lung function can take several weeks to recover to baseline, <strong>and</strong> quality<br />

<strong>of</strong> life declines drastically. 2 The Pharmaco<strong>the</strong>rapy Management <strong>of</strong> COPD Exacerbation measure<br />

evaluates whe<strong>the</strong>r patients received appropriate medical treatment after an event <strong>and</strong> assesses<br />

effective outpatient management <strong>of</strong> <strong>the</strong> disease.<br />

• CoPD exacerbations are responsible for<br />

<strong>the</strong> majority <strong>of</strong> CoPD-related costs from<br />

unscheduled physician <strong>and</strong> emergency<br />

room visits <strong>and</strong> hospitalizations. 2<br />

• Exacerbations have contributed to an<br />

increase in CoPD-related mortality, from<br />

21.4 to 43.3 deaths per 100,000 persons<br />

in <strong>the</strong> U.S. in <strong>the</strong> last two decades. 1<br />

• According to <strong>the</strong> Global Initiative for<br />

Chronic obstructive lung Disease<br />

guidelines, inhaled bronchodilators are<br />

a cornerstone <strong>of</strong> treatment for CoPD<br />

exacerbation. 3,4 Short-term corticosteroid<br />

<strong>the</strong>rapy may also be required. 5,6<br />

<strong>the</strong> Case for <strong>Improvement</strong><br />

• CoPD exacerbations are estimated to<br />

result in approximately 110,000 deaths<br />

<strong>and</strong> more than 500,000 hospitalizations<br />

annually. More than $18 billion is spent<br />

on direct costs every year. 4 Hospital<br />

admissions for CoPD exacerbations<br />

average a 10-day length <strong>of</strong> stay, at a cost<br />

<strong>of</strong> $10,000 per stay. 5,6<br />

• Approximately one-third <strong>of</strong> patients<br />

discharged from <strong>the</strong> emergency department<br />

with acute exacerbations have recurrent<br />

symptoms within 14 days, <strong>and</strong> 17 percent<br />

relapse <strong>and</strong> require hospitalization—a<br />

good indicator that patients are not getting<br />

<strong>the</strong> care <strong>the</strong>y require. 3<br />

• benefits <strong>of</strong> appropriate medical treatment<br />

include decreased duration <strong>of</strong> hospital<br />

stays <strong>and</strong> less likelihood <strong>of</strong> treatment<br />

failure. Patients also exhibit decreased<br />

frequency <strong>of</strong> exacerbations <strong>and</strong> maintain<br />

longer disease-free intervals. 5

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