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PROCEEDINGS OF THE 7 INTERNATIONAL ... - Fizika

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MEDICAL PHYSICS IN <strong>THE</strong> BALTIC STATES 7 (2009)<br />

Proceedings of International Conference “Medical Physics 2009”<br />

8 - 10 October 2009, Kaunas, Lithuania<br />

MODELING <strong>OF</strong> <strong>THE</strong> RESPONSE <strong>OF</strong> IONIZATION CHAMBERS IN<br />

RADIO<strong>THE</strong>RAPY FIELDS WITH DINAMIC INTENSITY MODULATION<br />

Sandija PLAUDE * , Sergey POPOV * , Arturs MEIJERS * , Albert MILLER ** , Yuri DEKHTYAR ***<br />

* Latvian Oncology Centre of Riga Eastern Clinical University Hospital, Riga, Latvia<br />

** Vilnius University Oncology Institute, Vilnius, Lithuania<br />

*** Riga Technical University, Riga, Latvia<br />

Abstract: Ionization chamber (IC) is the most common and trusted radiation detector in Radiotherapy (RT) dosimetry.<br />

However, due to its finite size detector volume have an impact on point dose measurements especially in a penumbra<br />

and regions of high dose gradients inside Intensity Modulated Radiotherapy (IMRT) fields. The aim of this work is to<br />

make a comparison of measured and modeled point doses in the case of dynamic radiotherapy using IC`s of different<br />

active volumes, to evaluate magnitude of the chamber volume effect on the discrepancy between the calculated and the<br />

measured dose.<br />

Keywords: Point dose measurements, ionization chamber, IMRT<br />

1. Introduction<br />

Although there are many different radiation detectors<br />

used in IMRT dosimetry, the IC is still the gold standard<br />

in point dose measurements [1]. In three-dimensional<br />

(3D) conformal radiotherapy and in IMRT beam’s<br />

central axis (CAX) is usually used for absolute dose<br />

measurements. In the case of conformal radiotherapy<br />

usually there is a uniform dose distribution and low<br />

dose gradients inside the field, while in the intensity<br />

modulated field there could be a region of a high dose<br />

gradient as well as areas of low dose.<br />

Moran et al. within the framework of their study created<br />

a dose-gradient analysis tool for IMRT quality<br />

assurance (QA) that helps to avoid dose measurements<br />

in high dose gradients and low dose regions [2].<br />

However in the case of IMRT there are low dose<br />

regions and high dose gradients inside the radiation field<br />

moreover inside the Planning Target Volume (PTV), so<br />

it is very important to check the dose also in these areas.<br />

Many authors suggest that in case of IC over –<br />

responses or under – responses this effect will smooth<br />

out when all treatment fields are analyzed together [3].<br />

Although in the previously mentioned study in almost<br />

all situations when IC over or under – responses were<br />

identified, this can be used only to understand a<br />

behaviour of IC in certain treatment conditions but not<br />

to analyze a treatment plan for the patient.<br />

One of the most common sources of errors in dose<br />

52<br />

determination in case of IMRT is the variation of the<br />

measurement conditions from the reference ones [4, 5].<br />

Sánchez – Doblado et al. found a general correlation<br />

between the IC position relative to a segment and the<br />

derived correction factor, c, that indicate the difference<br />

between reference and measurement conditions.<br />

Almost in all studies about IMRT dosimetry Monte –<br />

Carlo (MC) simulation is used as a model for theoretical<br />

dose calculation. From the other hand there are attempts<br />

to introduce in clinical routine methods of absolute<br />

dosimetry in IMRT fields, employing simple chamber<br />

volume Dose-Volume Histogram based correction, in<br />

that way correcting chamber volume effect [6].<br />

Aim of present study is to verify correctness of dose<br />

modelling using simple geometrical model for<br />

evaluation of the chamber volume effect.<br />

2. Material and Methods<br />

2.1. Accelerator and collimator<br />

Measurements were performed on linear accelerator<br />

Clinac 2100C/D (Varian Medical Systems, USA). This<br />

is a dual photon energies accelerator equipped with a<br />

multileaf collimator (MLC). The MLC has 40 opposed<br />

leaf pairs. Each MLC leaf is 6 cm thick made from<br />

wolfram with leaf transmission 1.5% - 2.0% for 6MV<br />

photon energy. A width of each MLC leaf is 1 cm at the<br />

level of the isocenter.

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