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Telomeric G4 Discussion Apart from protective role, in in vitro primer extension assays to study telomere elongation, intermolecular G4 are highly stable and are excellent substrates when compared to intramolecular G4 for ciliate telomerase. From yeast to humans, telomerase could form <strong>di</strong>mers or multimers and this has been shown to regulate the catalytic activity of telomerase enzyme [216,217]. It should be determined if telomerase <strong>di</strong>merization can elongate more than one telomere simultaneously. 98
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UNIVERSITÀ DEGLI STUDI DI MILANO-B
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Contents
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Abstract
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Riassunto
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Introduction
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Introduction In Saccharomyces cerev
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Introduction Figure 3: A: Diagram s
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Introduction The Replication Protei
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Introduction Rap1 C terminal is ess
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Introduction and highest at G1 phas
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Introduction cleaves the RNA strand
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Introduction In the G1 cell cycle p
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Introduction impaired, and nuclease
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Introduction functionally compromis
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Introduction increasing the interac
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Introduction Similarly in fission y
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Introduction constitutive phosphory
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Shelterin-Like Proteins and Yku Inh
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Bonetti et. al., PLoS Genet. 2010 M
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Page 57 and 58: Bonetti et. al., PLoS Genet. 2010 M
Page 65 and 66: Rif1 Supports the Function of the C
Page 67 and 68: Anbalagan et. al., PLoS Genet. 2011
Page 95 and 96: References Anbalagan et. al., PLoS
Page 99: Anbalagan et. al., PLoS Genet. 2011
Page 102 and 103: Discussion The DNA damage proteins
Page 104 and 105: Discussion An hypothesis for the sp
Page 106 and 107: Discussion Figure 14: Model, part 2
Page 110 and 111: References 1. Hayflick L (1965) The
Page 112 and 113: References that is required for tel
Page 114 and 115: References 51. Surovtseva YV, Churi
Page 116 and 117: References telomere elongation in S
Page 118 and 119: References 100. Walker JR, Corpina
Page 120 and 121: References 124. Gravel S, Larrivée
Page 122 and 123: References 147. Lamarche BJ, Orazio
Page 124 and 125: References 170. Boltz KA, Leehy K,
Page 126 and 127: References 194. Nimonkar AV, Ozsoy
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