DEPARTMENT OF ANESTHESIOLOGY ANNUAL REPORT

CLINICAL RESEARCH
Kwatra, Madan M., Ph.D.
Effect of cardiopulmonary bypass (CPB) on signaling
through G protein-coupled receptors in peripheral blood
mononuclear cells (PBMCs). A pilot study.
Effect of age on g-protein coupled receptor system in
human peripheral blood mononuclear cells.
MacLeod, David B., M.B., B.S., FRCA
Paravertebral nerve blockade vs. local infiltration for
iliac crest bone graft.
Martin, Gavin, M.B., Ch.B., FRCA
A phase 3, randomized, double-blind, placebo controlled,
parallel group, dose-ranging study to evaluate the safety
& efficacy of a single epidural dose of sustained-release
encapsulated morphine (SKY0401) in the management
of post-operative pain in patients undergoing hip
arthroplasty.
A multi-center clinical outcome and cost-finding study
of the use of the HemoSonic 100 cardiac output monitor
compared to routine care in spinal surgery patients.
Mathew, Joseph P., M.D.
Assessment of myocardial and splanchnic organ perfusion
during coronary artery bypass graft surgery (CABG)
by contrast echocardiography.
Inflammation, coagulation and cognitive decline after
cardiac surgery.
A phase 2 randomized, double-blind, placebo-controlled
study of the effect of h5G1.1-scFv on total mortality and
adverse cardiovascular ischemic outcomes in patients
undergoing cardiopulmonary bypass.
Moon, Richard E., M.D., C.M., M.Sc., FRCP(C),
FACP, FCCP
An evaluation of 3-hydroxy-3-methylglutaryl (HMG)-CoA
reductase inhibitors on hypoxic pulmonary vasoconstriction.
The effects of hyperbaric exercise on pulmonary gas
exchange in older divers.
The relationship of s-nitrosohemoglobin and hypoxicvasoconstriction
over a prolonged altitude exposure.
Effects of abdominal surgery on signaling through G protein-coupled
receptors.
112 CLINICAL RESEARCH
Moretti, Eugene W., M.D.
Effect of surgery on mangesium stores.
The association of apolipoprotein gene polymorphism
with acute renal failure in the critically ill.
An evaluation of the antimicrobial properties of the
Vantex central venous catheter with Oligon material.
Muir, Holly A., M.D., FRCP(C)
A trial to compare the safety & efficacy of labor and
delivery analgesia using ropivacaine alone and in combination
with fentanyl versus bupivacaine in combination
with fentanyl during epidural administration (CARE).
Murdoch, John A.C., M.B., Ch.B., B.Sc.
Recovery from abdominal aortic aneurysm repair:
comparison between transabdominal and endovascular
surgical repair.
Newman, Mark F., M.D.
Neuromonitoring to improve quality and decrease cost
of coronary artery bypass graft surgery.
A prospective trial of a temperature management system
in OPCAB cardiac surgery and the effect of OPCAB on the
systemic inflammatory response. Intraoperative cardiac
function, and postop renal, pulmonary and cognitive
function.
A phase II, multicenter, placebo-controlled, randomized,
double-blind, dosing regimen optimization and dose
escalation study to evaluate safety, toleration and clinical
pharmacology of CP-597,396 administered for vascular
surgery.
The role of genetics on cardiac surgery outcomes.
A prospective trial of a temperature management system
in OPCAB cardiac surgery.
A randomized double blind placebo controlled study of
neuroprotection with lidocaine during cardiac surgery.
Peri-operative genetic outcome (POGO-1) Trial
Effectiveness of 2.7 g PFC/kg of AF0144 to augment intraoperative
autologous donation in CABG with CPB.
The effect of off pump coronary artery bypass (OPCAB)
on cognitive function - one year longitudinal follow-up
Genetic basis of cognitive decline after surgery - five year
longitudinal study.
Randomized trial of a temperature management system
during routine cardiac surgery.