DEPARTMENT OF ANESTHESIOLOGY ANNUAL REPORT

Magnesium neuroprotection in cardiac surgery (MANIC).
Genetic basis of cognitive decline after anesthesia and
surgery.
An open label pharmacokinetic study to evaluate the
pharmacokinetics, pharmacodynamics, toleration and
safety of CP-597, 396 administered for 24 hours in subjects
undergoing coronary artery bypass graft (CABG) surgery.
Nielsen, Karen C., M.D.
A cohort study assessing the effectiveness and costs of
total knee arthroplasty performed under continuous
peripheral nerve blocks in an ambulatory setting.
Postoperative pain relief after open shoulder surgery: A
non-randomized controlled trial comparing continuous
interscalene brachial plexus blockade in the 23 hour
recovery care center vs. home catheter program.
A randomized prospective trial comparing paravetebral
nerve block and general anesthesia for surgical treatment
of breast cancer pilot study.
A randomized controlled trial assessing the effectiveness
of general anesthesia vs. lumbar plexus/sciatic nerve
block vs. lumbar plexus/sciatic nerve block with continuous
home catheter for postoperative pain control after
knee surgeries.
A comparison of low dose lidocaine and ropivacaine
spinal blocks in the ambulatory setting.
Olson, Ronald P., M.D., CCFP
Hyperkalemia in patients completing vascular surgery:
prevalence and morbidity.
Prevalence of abnormal preoperative hemoglobin levels.
Olufolabi, Adeyemi J., M.B., B.S., FRCA
Is there an increase in the incidence cesarean sections in
mothers with positive HIV following evidence of reduced
vertical transmission to the neonate?
A randomized, prospective double-blind comparison of
the efficacy of generic propofol with diprivan.
The use of near infrared spectroscopy to determine
oxygenation in the placental tissue.
Efficacy of BIS monitor-eirected verbal therapeutic
suggestion during general anesthesia for abdominal
hysterectomy.
CLINICAL RESEARCH
Podgoreanu, Mihai V., M.D.
The role of genetic polymorphisms of the beta 2 adrenergic
receptors in cardiac surgery outcome.
Reves, J.G., M.D.
Use of discarded materials.
Hemodilution and brain protection in cardiac surgery.
Aging and post cardiopulmonary bypass afterdrop.
Reynolds, James D., Ph.D.
Enhanced research training for medical students.
Ross, Allison K., M.D.
Ropivacaine for caudal analgesia in children.
Optimal ropivacaine concentration for sciatic nerve block
in children.
Schultz, John R., M.D.
Comparing a modified ECG to the standard three lead
ECG for detecting myocardial ischemia and p wave
height in high risk patients in the non-invasive cardiac
diagnostic laboratory.
Motion induced artifactual ventilatory absence-motion
induced artifact (MIA).
Schwinn, Debra A., M.D.
Adrenergic receptor polymorphisms and hypertension.
Adrenergic receptor mutations associated with
hypertension.
Why do cardiac surgical patients choose to participate
or not participate in medical research studies?
Does cardiopulmonary bypass with cardioplegic arrest
cause adrenergic receptor desensitization in adults with
chronic disease undergoing elective cardiac surgery?
Slaughter, Thomas F., M.D.
Mechanisms of aprotinin-mediated hemostasis.
Somma, Jacques, M.D., FRCP(C)
Research on age, effect and interaction between propofol
and remifentanil.
A double blind randomized study to compare the
analgesia and respiratory effect of dexmedetomidine
and remifentanil.
A randomized, double-blind, parallel-design, placebo
and active controlled multicenter ascending dose ranging
study of the safety and efficacy of single doses of Org
41739 in the treatment of post-operative pain in ASA class
I and II surgical patients.
CLINICAL RESEARCH 113