DEPARTMENT OF ANESTHESIOLOGY ANNUAL REPORT

CLINICAL ACTIVITIES
years, has combined clinical responsibilities
and research. Fellows for 2000
have been David Hendricks, M.D.
(January-June), Charles Gleaton, M.D.
(January-June) and John Freiberger,
M.D. (July-December). Klaus Torp,
M.D., a visiting Fellow from Mayo Clinic
for three months completed a study of
the effect of simvastatin on hypoxic
pulmonary vasoconstriction.
The full time nursing staff are:
Kevin L. Kraft, RN
John H. Rice, RN (Head Nurse)
Roberta E. Rose, RN
A number of part time nurses also
participate in patient care.
Teaching
For the second year, a 37-hour course
in the Physiology of Extreme Environments
was given (CBI206/ANE245.
Duke University Graduate and Medical
School. Fall Semester 2000: Richard D.
Vann, Ph.D., Course Director). In addition
to lectures on the physiology of
high pressure, hyperoxia, hypoxia,
immersion and hypothermia, the course
included practical laboratories on diagnosis
and management of hyperbaric
and diving related emergencies. The
course was made available not only for
the fellows and students working in the
Center, but also for faculty, residents
and fellows in the Department.
The Center also participates in the
teaching for the Anesthesiology and
Environmental Physiology section for
the third year medical student curriculum.
Two third year medical students
(Jason Archibald and Heather
Mummery) are currently working in
the center on human experiments at
altitude and during diving. Interns regularly
rotate onto the Hyperbaric Service,
as do fellows in critical care and a number
of medical students. Hyperbaric
Grand Rounds in 2000 included the
following lectures: DAN: Beginnings –
Today – Tomorrow; Australian Experience
on CO Poisoning; Marine Biotoxins;
Pulmonary Alveolar Proteinosis;
Biochemical Markers of Tissue Damage
in Response to Bubbles and Other
56 CLINICAL ACTIVITIES
Injuries; Bubble Trouble: Surface Tension,
Surfactants and Gas Nuclei; High
Altitude Expeditions on Mt. Everest.
A monthly conference on diving medicine
is held at the DAN building.
Academic Productivity
PHOTO BY STEVE BARNETT
A hyperbaric technician from the
Center for Hyperbaric Medicine and
Environmental Physiology uses Doppler
device on a DAN research volunteer
after a simulated dive in the chamber.
The investigators in the Hyperbaric
Center are pursuing studies on the
mechanisms by which investigations
into the effects of altered environmental
conditions (altitude and diving) affect
on human physiology, and into the
biology of oxygen and nitric oxide at
different gas pressures. Investigators
in the Center include the following:
Peter B. Bennett, Ph.D., D.Sc
Department of Anesthesiology
Martha Sue Carraway, M.D.
Department of Medicine
Guy deLisle Dear, M.B., FRCA
Department of Anesthesiology
Ivan T. Demchenko, D.Sc.
Department of Anesthesiology
Petar J. Denoble, M.D., Ph.D.
Department of Anesthesiology
Habib El-Moalem, Ph.D.
Department of Anesthesiology
Wayne A. Gerth, Ph.D.
Department of Anesthesiology
E.N. Grayck, M.D.
Deptartment of Pediatric Critical
Care
Y.C.T. Huang, M.D.
Department of Medicine
T. McMahon, M.D.
Department of Medicine
Richard E. Moon, M.D., C.M., M.Sc.,
FRCP(C), FACP, FCCP
Departments of Anesthesiology
and Medicine
Carl F. Pieper, D.P.H.
Deptartment of Biometry
Claude A. Piantadosi, M.D.
Departments of Anesthesiology
and Medicine
Neal W. Pollock, Ph.D.
Department of Anesthesiology
Herbert A. Saltzman, M.D.
Department of Medicine
Bryant W. Stolp, M.D., Ph.D.
Department of Anesthesiology
and Cell Biology
Hagir B. Suliman, D.V.M., Ph.D.
Department of Anesthesiology
Edward D. Thalmann, M.D.
Department of Anesthesiology
D.M. Uguccioni, M.Sc.
Department of Anesthesiology
Richard D. Vann, Ph.D.
Department of Anesthesiology
K. Welty-Wolfe, M.D.
Department of Medicine
The following projects were underway
in 2000:
Acute Lung Injury-Mechanisms and
Therapy (Drs. Piantadosi, Welty-Wolf,
Carraway)
Animal models have been developed
to study acute lung injury due
to oxygen toxicity and sepsis. Methods
of assessment include gas exchange
(blood gases and multiple inert gas
elimination), mechanics, lung morphometry
and measures of the pulmonary
inflammatory response.