Muscarinic M1, M3, Nicotinic,GABAA and GABAB Receptor ...

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The given mean pixel value is the net value which is deducted from the negative control pixel value. STATISTICS Statistical evaluations were done by ANOVA using InStat (Ver.2.04a) computer programme. Linear regression Scatchard plots were made using SIGMA PLOT (Ver 2.03). Sigma Plot software (version 2.0, J<strong>and</strong>el GmbH, Erkrath, Germany). Relative Quantification Software was used for analyzing Real- Time PCR results. 57
Results BODY WEIGHT AND BLOOD GLUCOSE LEVEL Streptozotocin induced diabetic rats showed a significant (p
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MUSCARINIC M1, M3, NICOTINIC, GABAA
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ACKNOWLEDGEMENT To the Almighty God
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Seema Chandran, Ms. Neema Ani Manga
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ABBREVIATIONS 5-HIAA 5 Hydroxy indo
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PFC Prefrontal cortex PLC Phospholi
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GABAC Receptors 34 Glutamic Acid De
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Behavioural response of control and
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the cerebral cortex of control and
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Muscarinic M1 receptor analysis Sca
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REAL TIME-PCR ANALYSIS 81 Real Time
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Real Time PCR analysis of GABAAα1
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pancreas of control and experimenta
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utilization is decreased in the bra
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impairment, coma or seizure (Cryer,
Page 31 and 32: achieving optimal blood sugar contr
Page 33 and 34: OBJECTIVES OF THE PRESENT STUDY 1.
Page 35 and 36: Literature Review Diabetes mellitus
Page 37 and 38: 12 Literature Review from the adren
Page 39 and 40: 14 Literature Review Hypoglycemic c
Page 41 and 42: 16 Literature Review respectively)
Page 43 and 44: 18 Literature Review in extracellul
Page 45 and 46: 20 Literature Review substrates in
Page 47 and 48: 22 Literature Review nucleus, altho
Page 49 and 50: 24 Literature Review al., 1990; Lev
Page 51 and 52: 26 Literature Review muscarinic M2
Page 53 and 54: Signal transduction by muscarinic a
Page 55 and 56: 30 Literature Review nicotinic acet
Page 57 and 58: GABAA Receptors 32 Literature Revie
Page 59 and 60: 34 Literature Review GABAB-mediated
Page 61 and 62: 36 Literature Review (Erlander et a
Page 63 and 64: 38 Literature Review which could be
Page 65 and 66: 40 Literature Review administration
Page 67 and 68: 42 Literature Review the hippocampu
Page 69 and 70: 44 Literature Review understanding
Page 71 and 72: Confocal Dyes Rat primary antibody
Page 73 and 74: antipyryl)-p-benzo quinoneimine. Th
Page 75 and 76: was analyzed. Data was expressed as
Page 77 and 78: ANALYSIS OF THE RECEPTOR BINDING DA
Page 79 and 80: Taqman probes of muscarinic M1, M3,
Page 81: Taylor, 1968). The islets were isol
Page 85 and 86: 60 Results IIH and C + IIH rats sho
Page 87 and 88: Real Time-PCR analysis of muscarini
Page 89 and 90: Real Time PCR analysis of SOD 64 Re
Page 91 and 92: 66 Results GABAAα1 receptor antibo
Page 93 and 94: 68 Results compared to diabetic gro
Page 95 and 96: 70 Results compared to diabetic rat
Page 97 and 98: 72 Results Muscarinic M3 receptor a
Page 99 and 100: Muscarinic M3 receptor analysis 74
Page 101 and 102: 76 Results group, α7 nAChR mRNA si
Page 103 and 104: 78 Results diabetic rats. In C + II
Page 105 and 106: Muscarinic M1 receptor analysis 80
Page 107 and 108: Real Time-PCR analysis of α7 nAChR
Page 109 and 110: Real Time PCR analysis of phospholi
Page 111 and 112: HIPPOCAMPUS Total muscarinic recept
Page 113 and 114: 88 Results IIH and C + IIH group sh
Page 115 and 116: 90 Results group, GLUT3 mRNA signif
Page 117 and 118: 92 Results α7 nACh receptor antibo
Page 119 and 120: GABA receptor analysis 94 Results S
Page 121 and 122: 96 Results control. D + IIH and C +
Page 123 and 124: Discussion Glucose is the principal
Page 125 and 126: 100 Discussion The ability to sense
Page 127 and 128: 102 Discussion The Y-maze test is a
Page 129 and 130: 104 Discussion CHOLINERGIC ENZYME A
Page 131 and 132: 106 Discussion Pancreas Insulin sec
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108 Discussion 2003). Cholinergic m
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110 Discussion brain for learning,
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112 Discussion hypoglycemia on brai
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114 Discussion shows impaired expre
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116 Discussion glycemic control is
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118 Discussion release (Ilcol et al
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120 Discussion al., 1992), it has t
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122 Discussion metabolic cycles are
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124 Discussion al., 1988). Low bloo
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126 Discussion modulate the second
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128 Discussion between excitation a
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130 Discussion hypoglycemic seizure
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132 Discussion Insulin secretion fr
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134 Discussion hyper and hypoglycem
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136 Discussion receptors in glucose
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138 Discussion exacerbated by recur
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140 Discussion Haces et al., 2010).
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142 Discussion hypoglycemic and dia
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144 Discussion transcription factor
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Summary 1. Insulin induced hypoglyc
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148 Summary specific antibodies con
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150 Summary 16. Transcription facto
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References Abdelmalik PA, Shannon P
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Akwa Y, Ladurelle N, Covey F, Bauli
Page 181 and 182:
Arison RN, Ciaccio EI, Glitzer MS,
Page 183 and 184:
Balters E, Francesco M. (2002). New
Page 185 and 186:
Bettler B, Kaupmann K, Mosbacher J,
Page 187 and 188:
Boess FG, De Vry J, Erb C, Flessner
Page 189 and 190:
Brezenoff HE, Xiao YF. (1986). Acet
Page 191 and 192:
Caulfield MP, Birdsall NJM. (1998).
Page 193 and 194:
Cherubini E, Martina M, Sciancalepo
Page 195 and 196:
Cryer PE. (2002b). The pathophysiol
Page 197 and 198:
Delgado Esteban M, Almeida A, Bolan
Page 199 and 200:
Dutar P, Nicoll RA. (1989). Pharmac
Page 201 and 202:
Exton JH, Jefferson LS, Butcher RW,
Page 203 and 204:
Frier B. (2000). Hypoglycaemia—cl
Page 205 and 206:
Gerich JE, Schneider V, Dippe SE, L
Page 207 and 208:
Golding DW, Pow DV. (1990). Neurose
Page 209 and 210:
Haddad GG, Jiang C. (1993). Mechani
Page 211 and 212:
Havel PnJ, Dunning BnE, Verchere Cn
Page 213 and 214:
Hsu KS, Huang CC, Gean PW. (1995).
Page 215 and 216:
Johnson E, Deckwerth T. (1993). Mol
Page 217 and 218:
Kanjhan R, Housley GD, Burton LD, C
Page 219 and 220:
Kelley GG, Zawalich KC, Zawalich WS
Page 221 and 222:
Krnjevic K. (1993). Central choline
Page 223 and 224:
Lackovic Z, Salkovic M, Kuci Z, Rel
Page 225 and 226:
Lipton P. (1999). Ischemic cell dea
Page 227 and 228:
Mares P, Kubova H, Zouhar A, Folber
Page 229 and 230:
McCulloch DK, Raghu PK, Koerker DJ,
Page 231 and 232:
Miyakawa T, Yamada M, Duttaroy A, W
Page 233 and 234:
Nusser Z, Sieghart W, Somogyi P. (1
Page 235 and 236:
Paramo B, Hernández-Fonseca K, Est
Page 237 and 238:
Peeyush KT, Savitha B, Sherin A, An
Page 239 and 240:
Quan L, Meili G, Chang BS, Lowenste
Page 241 and 242:
Robinson R, Krishnakumar A, Paulose
Page 243 and 244:
Salkovic M, Lackovic Z. (1992). Bra
Page 245 and 246:
Scheucher A. Alvarez AL, Torres N,
Page 247 and 248:
(2002). Sulfonylurea receptor type
Page 249 and 250:
Steriade M. (1996). Arousal: revisi
Page 251 and 252:
Takayama C, Inoue Y. (2003). Normal
Page 253 and 254:
Unger J, McNeill TH, Moxley RT 3rd,
Page 255 and 256:
pentabromodiphenyl ether (PBDE 99).
Page 257 and 258:
Weiner DM, Levey AI, Brann MR. (199
Page 259 and 260:
Wredling R, Levander S, Adamson U,
Page 261 and 262:
Zhao W, Chen H, Xu H, Moore E, Meir
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6. Anju T R, Pretty Mary Abraham, S
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Body weight (gm) 300 250 200 150 10
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Figure-3 Blood glucose levels at di
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Figure-5 Behavioural response of co
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Figure-7 Scatchard analysis of [ 3
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Figure-11 Real Time PCR amplificati
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C D + IIH Figure--25 Muscarinic M1
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Figure--27 α 7 nACh receptor expre
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Figure--47 Muscarinic M1 receptor e
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Figure--49 α7 nicotinic acetylchol
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Figure--71 α7 nicotinic acetylchol
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C Figure--93 GABAAα1 receptor expr
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Figure-101 Real Time PCR amplificat
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Figure—113 Muscarinic M3 receptor
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Figure--115 GABAAα1 receptor expre
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Figure-117 Scatchard analysis of [
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Figure-119 Scatchard analysis of [
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Figure-131 Muscarinic M1 receptor e
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C D + IIH Figure-133 GABAAα1 recep
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