Amphetamine and Related Drugs

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Most Common Amphetamines There are a large number of amphetamines which are controlled substances. Of these, the most commonly encountered in the forensic science laboratory are amphetamine (1), ( ), methylamphetamine (2), ), 3,4- 3,4 methylenedioxyamphetamine (MDA) (3), ( ), 3,4- 3,4 methylenedioxymethylamphetamine (MDMA) (4)and ( )and 3,4-methylenedioxyethylamphetamine 3,4 methylenedioxyethylamphetamine (MDEA) (5). ( ). In addition, there are a wide variety of structurally related analogues which can be synthesized. 4/27/2009 ١٤
4/27/2009 ١٥
Page 1 and 2: Amphetamine and Related Drugs 4/27/
Page 3 and 4: Cocaine Amphetamines Methcathinone
Page 5 and 6: Marijuana Hashish Hashish Oil Canna
Page 7 and 8: Other Categories Inhalants like amy
Page 9 and 10: Schedule I amphetamine derivatives
Page 11 and 12: Schedule III • The drug or other
Page 13: Schedule V • The drug or other su
Page 17 and 18: As use of amphetamines spread, so d
Page 19 and 20: To meet the ever-increasing ever in
Page 21 and 22: The effects of amphetamines, especi
Page 23 and 24: A colourless, mobile, slowly volati
Page 25 and 26: Amfetamine Sulfate Synonyms. Amphet
Page 27 and 28: 4/27/2009 ٢٧
Page 29 and 30: Therapeutic concentration After no
Page 31 and 32: Toxicity The estimated minimum leth
Page 33 and 34: Methylenedioxymethamfetamine Stimul
Page 35 and 36: N,α-Dimethyl Dimethyl-1,3,benzodio
Page 37 and 38: Colour Test. Marquis Reagent—bla
Page 39 and 40: Therapeutic concentration 8 healthy
Page 41 and 42: Toxicity Fatalities with doses of 3
Page 43 and 44: Metamfetamine Central Stimulant Syn
Page 45 and 46: Metamfetamine Hydrochloride Propri
Page 47 and 48: Disposition in the Body Readily abs
Page 49 and 50: Half-life Half life Plasma half-li
Page 51 and 52: A viscous, colourless oil. B.p. is
Page 53 and 54: Disposition in the Body. It is abs
Page 55 and 56: Methylenedioxyamfetamine Hallucinog
Page 57 and 58: Why are adulterants and diluants ad
Page 59 and 60: Sampling and Physical Description o
Page 61 and 62: Recording the ballistic features of
Page 63 and 64: Having carried out the control proc
Page 65 and 66:
For tableted materials, homogenizat
Page 67 and 68:
The sample should be dissolved as f
Page 69 and 70:
The pooled sulfuric acid extracts a
Page 71 and 72:
Urine analyzed by Test B shows an i
Page 73 and 74:
Aspirate off the lower chloroform l
Page 75 and 76:
Add 20 ml chloroform and shake for
Page 77 and 78:
Transfer the residue to a 3 ml micr
Page 79 and 80:
Dissolve the residues in 20 µl l o
Page 81 and 82:
Remove the developed plate and allo
Page 83 and 84:
Methamphetamine (Methedrine ( Methe
Page 85 and 86:
In addition, MDA, MDMA and MDEA giv
Page 87 and 88:
Thin-layer Thin layer Chromatograph
Page 89 and 90:
Colour test The Marquis test gives
Page 91 and 92:
System TC Plates: Plates: Silica ge
Page 93 and 94:
System TAE Plates: Plates: Silica g
Page 95 and 96:
Location reagents for systems TA, T
Page 97 and 98:
Dragendorff spray Yellow, orange, r
Page 99 and 100:
Mandelin’s Mandelin s reagent Thi
Page 101 and 102:
Acidified potassium permanganate so
Page 103 and 104:
Column: DB-5 DB 5 fused silica (30
Page 105 and 106:
Column: Chiralcel OD-RH OD RH (150
Page 107 and 108:
Definitive De nitive Identification
Page 109 and 110:
4/27/2009 ١٠٩
Page 111 and 112:
In order to alleviate this problem,
Page 113 and 114:
The reaction (see equation (2.1)) i
Page 115 and 116:
Quantification Quanti cation of Amp
Page 117 and 118:
The amphetamines (standards and sam
Page 119 and 120:
Derivatization 4/27/2009 ١١٩
Page 121:
Mass Spectra 44 91 40 42 65 45 39 4
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Amphetamine and Related Drugs

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