Amphetamine and Related Drugs

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Drug Schedules: Schedule I • The drug or other substance has a high potential for abuse. • The drug or other substance has no currently accepted medical use in treatment in the United States. • There is a lack of accepted safety for use of the drug or other substance under medical supervision. • Examples of Schedule I substances include heroin, lysergic acid diethylamide (LSD), marijuana, <strong>and</strong> methaqualone. methaqualone. 4/27/2009 ٨
Schedule I amphetamine derivatives 2,5-Dimethoxy 2,5 Dimethoxy-4-ethylamphetamine ethylamphetamine 2,5-Dimethoxyamphetamine 2,5 Dimethoxyamphetamine 3,4,5-Trimethoxyamphetamine 3,4,5 Trimethoxyamphetamine 3,4-Methylenedioxyamphetamine 3,4 Methylenedioxyamphetamine 3,4-Methylenedioxymethamphetamine 3,4 Methylenedioxymethamphetamine 4-Bromo Bromo-2,5 2,5-dimethoxyamphetamine dimethoxyamphetamine 4-Bromo Bromo-2,5 2,5-dimethoxyphenethylamine dimethoxyphenethylamine 4-Methoxyamphetamine Methoxyamphetamine 4-Methyl Methyl-2,5 2,5-dimethoxyamphetamine dimethoxyamphetamine 5-Methoxy Methoxy-3,4 3,4-methylenedioxyamphetamine methylenedioxyamphetamine 4/27/2009 ٩
Page 1 and 2: Amphetamine and Related Drugs 4/27/
Page 3 and 4: Cocaine Amphetamines Methcathinone
Page 5 and 6: Marijuana Hashish Hashish Oil Canna
Page 7: Other Categories Inhalants like amy
Page 11 and 12: Schedule III • The drug or other
Page 13 and 14: Schedule V • The drug or other su
Page 15 and 16: 4/27/2009 ١٥
Page 17 and 18: As use of amphetamines spread, so d
Page 19 and 20: To meet the ever-increasing ever in
Page 21 and 22: The effects of amphetamines, especi
Page 23 and 24: A colourless, mobile, slowly volati
Page 25 and 26: Amfetamine Sulfate Synonyms. Amphet
Page 27 and 28: 4/27/2009 ٢٧
Page 29 and 30: Therapeutic concentration After no
Page 31 and 32: Toxicity The estimated minimum leth
Page 33 and 34: Methylenedioxymethamfetamine Stimul
Page 35 and 36: N,α-Dimethyl Dimethyl-1,3,benzodio
Page 37 and 38: Colour Test. Marquis Reagent—bla
Page 39 and 40: Therapeutic concentration 8 healthy
Page 41 and 42: Toxicity Fatalities with doses of 3
Page 43 and 44: Metamfetamine Central Stimulant Syn
Page 45 and 46: Metamfetamine Hydrochloride Propri
Page 47 and 48: Disposition in the Body Readily abs
Page 49 and 50: Half-life Half life Plasma half-li
Page 51 and 52: A viscous, colourless oil. B.p. is
Page 53 and 54: Disposition in the Body. It is abs
Page 55 and 56: Methylenedioxyamfetamine Hallucinog
Page 57 and 58: Why are adulterants and diluants ad
Page 59 and 60:
Sampling and Physical Description o
Page 61 and 62:
Recording the ballistic features of
Page 63 and 64:
Having carried out the control proc
Page 65 and 66:
For tableted materials, homogenizat
Page 67 and 68:
The sample should be dissolved as f
Page 69 and 70:
The pooled sulfuric acid extracts a
Page 71 and 72:
Urine analyzed by Test B shows an i
Page 73 and 74:
Aspirate off the lower chloroform l
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Add 20 ml chloroform and shake for
Page 77 and 78:
Transfer the residue to a 3 ml micr
Page 79 and 80:
Dissolve the residues in 20 µl l o
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Remove the developed plate and allo
Page 83 and 84:
Methamphetamine (Methedrine ( Methe
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In addition, MDA, MDMA and MDEA giv
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Thin-layer Thin layer Chromatograph
Page 89 and 90:
Colour test The Marquis test gives
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System TC Plates: Plates: Silica ge
Page 93 and 94:
System TAE Plates: Plates: Silica g
Page 95 and 96:
Location reagents for systems TA, T
Page 97 and 98:
Dragendorff spray Yellow, orange, r
Page 99 and 100:
Mandelin’s Mandelin s reagent Thi
Page 101 and 102:
Acidified potassium permanganate so
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Column: DB-5 DB 5 fused silica (30
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Column: Chiralcel OD-RH OD RH (150
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Definitive De nitive Identification
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4/27/2009 ١٠٩
Page 111 and 112:
In order to alleviate this problem,
Page 113 and 114:
The reaction (see equation (2.1)) i
Page 115 and 116:
Quantification Quanti cation of Amp
Page 117 and 118:
The amphetamines (standards and sam
Page 119 and 120:
Derivatization 4/27/2009 ١١٩
Page 121:
Mass Spectra 44 91 40 42 65 45 39 4
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