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Amphetamine and Related Drugs

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Thin Layer Chromatography of<br />

<strong>Amphetamine</strong>s<br />

In order that the sample can be tested for the presence<br />

of amphetamines, a test solution must be prepared.<br />

The sample should be dissolved in a suitable solvent<br />

(methanol is commonly used) at a sample<br />

concentration of the order of 10 mgml −1 . This allows<br />

for the fact that many amphetamine samples at the<br />

‘street street level’ level are extremely weak, i.e. between 2 <strong>and</strong><br />

10% amphetamine in a matrix of adulterants <strong>and</strong><br />

diluants, diluants,<br />

giving a solution of approximately 0.2–1.0 0.2 1.0<br />

mgml −1 , namely a concentration at which the<br />

st<strong>and</strong>ards can be prepared.<br />

4/27/2009 ٦٦

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