Summer Undergraduate Research Program - Fred Hutchinson ...

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with cancer: Kaposi's Sarcoma-associated herpesvirus (Dr. M. Lagunoff, UW), and genomic integrity (Dr. B.D. Preston, UW), as well as the labs studying immunotherapies (Dr. D.J. Rawlings, UW), stem cells (Dr. H-P Kiem, FHCRC), and HIV (Dr. M. Emerman, FHCRC). I believe by obtaining a doctorate, I will gain a better set of tools to find meaning in the massive amounts of information we gain from technology. I also hope to contribute new information to the scientific community, understanding that even a small finding can serve as a vital piece in an unsolved puzzle. Based on my experiences and the joy I get from discussing scientific research with others, be it at a conference or at the dinner table, I have every desire to remain in academia. In the future, I see myself inspiring undergraduate students as a professor. Working under female scientists gave me confidence and encouraged me to pursue my dream to be a scientist; I can only hope to do the same for others. Meanwhile, I would enjoy helping to shape public science policy and bridge the gap between the scientific community and the general public. 131
Extra Personal Statement #7 My current PI insists that science is like boxing: if you get knocked down, you get up and fight again. To me, this is an inspiring but simple comparison. If we are picking sports, I say that science is like swimming. I swam for over a decade, and for my race of fifty seconds I trained five hours per day, five hundred hours per season. Through hard work I qualified for and competed at the NCAA Division I Championships and Olympic Trials. I learned that dedication, perseverance, and mental endurance are necessary to get results. Thus far, these lessons have translated well to research. As an undergraduate, I conducted honors thesis research in St. Olaf's Department of Neurobiology and Physiology, in Dr. Anne Freeburn's laboratory with the guidance of my adviser, Dr. Juan Garcia. My project constituted early steps in the elucidation of the cellular mechanism of menopausal hot flashes. Building on Dr. Garcia's work, I developed a mouse model and system of measurement for studying hot flashes. Using these animals, I identified colocalization in the estrogen receptor alpha and TREK-1 in the medial preoptic area of the mouse brain, a region involved in thermoregulation. TREK-1, a two pore domain potassium ion channel, is involved in temperature sensing and plays a role in neuronal stability. This identifies a potential role for estrogen action in thermoregulation and therefore a potential mechanism for dysregulation of heat sensing (hot flashes) in the estrogen-deficient state of menopause. The ultimate goal is to characterize the mechanism underlying hot flashes so that safe and effective therapies can treat these symptoms. This experience opened my eyes to biomedical research. I was excited to find in my fellow lab members a work ethic I had previously seen only in my teammates in swimming. I also enjoyed the logical yet creative process of working through problems both broad and narrow in scope. I was introduced to the day-to-day challenges of working in science; for example, my mice became increasingly adept at removing their temperature-sensing tail cuffs, so I had to stay ahead of their learning curve with new methods of attachment. Additionally, I liked that the ultimate aim of research is to further medical knowledge and capability, improving people’s health and wellbeing. Overall, I found research to be engaging, challenging, and rewarding, and I decided to pursue additional experience and training after completing my undergraduate degree. Since September of 2006 I have worked as a technician at the Drexel School of Medicine. I joined Dr. Jarvis Hans' laboratory when he brought his lab to Philadelphia from Baylor College of Medicine. Our lab investigates the role of estrogens and androgens in metabolism, diabetes and obesity. As the tech I have 132
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Summer Undergraduate Research Progr
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Contributors • Core Competencies
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Interpersonal Skills • Style, ton
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Weekly Writing Assignments Writing
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Writing Workshop 6
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Writing Workshop Content and Assign
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9. The number of the subject determ
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Audience Analysis Another crucial e
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confused here give the author somet
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Advice from Admissions Representati
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Beth O'Neil Director of Admissions
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Personal Statement Examples 22
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while at the same time advocating p
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am tested ten different breast canc
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Graduate School Personal Statement
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the challenge of stepping into an u
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I understand the profound influence
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One of my more memorable experience
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team with Drs. XX XXX and XX XXX, p
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where I help coordinate weekly ente
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them. Yet, the best doctors are not
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Why MD/PhD Essay Example #2 Why MD/
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Applying for Graduate School 58
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June Graduate School Research mento
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September Re-take the Graduate Scho
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How to Conduct a Literature Search
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menopausal symptoms, and perceived
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How to Write a Resume and Cover Let
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