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Summer Undergraduate Research Program - Fred Hutchinson ...

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Why MD/PhD Essay Example #1<br />

Why MD/PhD Essay Example #1<br />

I saw the Large Hadron Collider at CERN long before the Higgs Boson was<br />

discovered, when it was just a mess of defeated wires and metal, in repair only nine<br />

days after it came online in 20XX. Fortunately, I met the researchers at CERN at their<br />

best: hopeful and determined. Paradoxically, it was during my time here that I<br />

became interested in the biology because I was most excited by the implications of<br />

the work in physics for microbiology and nuclear medicine. At CERN, I also realized<br />

the increasingly interdisciplinary nature of science and its power as a unifying force<br />

that transcends national boundaries and language.<br />

Once I entered college, I joined a lab to further explore this nascent interest in<br />

biology. I began conducting research thinking that, as an undergraduate, I could not<br />

possibly discover anything new. But, after a summer in the lab, I presented a poster<br />

that changed the way the nuclear protein I studied was viewed. Yet, I also found the<br />

limitations of research. Because my in vivo experiments in Drosophila contradicted<br />

published in vitro predictions, I saw firsthand the limits of these kinds of<br />

approaches. As a result, I began to think about the implications of taking an overly<br />

simplified approach to understanding human disease. Indeed, this shortcoming can<br />

be especially problematic in the field that I am most interested in—the molecular<br />

and genetic mechanisms underlying developmental disorders.<br />

This interest arose in elementary school when I read June Wood’s series of books<br />

about a man named Punky, a character with Down syndrome. I subsequently began<br />

volunteering at a center for the developmentally disabled in 20XX. It was here that I<br />

began to realize that sometimes, physicians lack the tools to ease human suffering<br />

because interventions for developmental disorders are too often analgesic and not<br />

truly curative or preventative. After I began conducting research, I considered these<br />

deficiencies in medicine as opportunities for the integration of scientific research<br />

with clinical care. It is this synthesis of basic science and medicine that draws me to<br />

a career as a physician-­‐scientist.<br />

I see the duality of this approach to medicine and research as an incredible asset for<br />

both the patient and the provider. Physician-­‐scientists are equipped with the<br />

mindset of a clinician when working in the laboratory, as well as equally can<br />

understand the practical limitations of treatment for patients and appreciate the<br />

breadth of human biology. As a physician-­‐scientist, I hope to advance medicine<br />

through the combination of the components that first drew me into research and<br />

clinical medicine— innovative interdisciplinary approaches and collaboration.<br />

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