POTASSIUM CHLORIDE CAS N°: 7447-40-7

OECD SIDS POTASSIUM CHLORIDE
Date: 30-MAR-2003
5. Toxicity Substance ID: 7447-40-7
the normal range within 2-3 days. Organ weights and
water levels returned to normal limits in survivors
at two weeks after administration of KCl. KCl had
no effect on the amount of urinary acetone,
albumin, occult blood, bilirubin or glucose.
Source:
Norsk Hydro ASA
Reliability: (2) reliable with restrictions
Flag:
Key study for SIDS
28-FEB-2001 (14)
Type:
LDL0
Species:
rat
Strain:
Wistar
Sex:
not stated
Number of
Animals: 12
Vehicle:
other: none
Value:
2430 mg/kg body weight
Method:
other: acute toxicity
Year: 1929 GLP: no data
Test substance: as prescribed by 1.1-1.4, purity: chemical grade
Remarks:
A M/2 solution of KCl was administrated to the
animals. Clinical signs of acute poisoning in
animals included increased respiration and heart
action, and occasionally asphyxial convulsions.
Sub-acute poisoning produced convulsions. The
animals showed wide variation in the effects
produced by KCl, and survival from an average
lethal dose took place.
Source:
Norsk Hydro ASA
Reliability: (2) reliable with restrictions
Flag: non confidential
28-FEB-2001 (71)
Type:
LDL0
Species:
guinea pigs
Strain:
Sex:
not stated
Number of
Animals: 14
Vehicle:
other: none
Value:
2500 mg/kg body weight
Method:
other: acute toxicity
Year: 1929 GLP: no data
Test substance: as prescribed by 1.1-1.4, purity: chemical grade
Remarks:
A M/2 solution of KCl was administrated to the
animals. Clinical signs of acute poisoning in
animals included increased respiration and heart
action, and occasionally asphyxial convulsions.
Sub-acute poisoning produced convulsions. The
animals showed wide variation in the effects
produced by KCl, and survival from an average
lethal dose took place.
Source:
Norsk Hydro ASA
Reliability: (2) reliable with restrictions
Flag:
non confidential
28-FEB-2001 (71)
Type:
Species:
LDL0
sheep
64
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