POTASSIUM CHLORIDE CAS N°: 7447-40-7

OECD SIDS POTASSIUM CHLORIDE
Date: 30-MAR-2003
5. Toxicity Substance ID: 7447-40-7
Type:
Species/strain:
LD50
mouse/Cobs Charles River
Route of
Administration: i.v.
Exposure time: 24 hr
Value:
117 mg/kg
Method:
other: acute toxicity
Year: 1975 GLP: no data
Test substance: as prescribed by 1.1-1.4, purity: not stated.
Remarks:
Groups of ten animals were injected 0.5 ml KCl
solution/20 g body weight.
Source:
Norsk Hydro ASA
Reliability: (2) reliable with restrictions
Flag:
non confidential
01-MAR-2001 (9)
Type:
LDL0
Species/strain: rat/Wistar
Route of
Administration: i.p.
Exposure time:
Value:
825 mg/kg body weight
Method:
other: acute toxicity
Year: 1929 GLP: no data
Test substance: as prescribed by 1.1-1.4, purity: chemical grade.
Remarks: A M/2 solution of KCl was administrated to 12
animals by means of a catheter. Clinical signs of
acute poisoning in animals included increased
respiration and heart action, and occasionally
asphyxial convulsions. Sub-acute poisoning produced
convulsions. The animals showed wide variation in
the effects produced by KCl, and survival from an
average lethal dose took place.
Source:
Norsk Hydro ASA
Reliability: (2) reliable with restrictions
Flag:
non confidential
01-MAR-2001 (71)
Type:
LDL0
Species/strain: guinea pig
Route of
Administration: i.p.
Exposure time:
Value:
900 mg/kg body weight
Method:
other: acute toxicity
Year: 1929 GLP: no data
Test substance: as prescribed by 1.1-1.4, purity: chemical grade.
Remarks: A M/2 solution of KCl was administrated to 14
animals by means of a hypodermic syringe. Clinical
signs of acute poisoning in animals included
increased respiration and heart action, and
occasionally asphyxial convulsions. Sub-acute
poisoning produced convulsions. The animals showed
wide variation in the effects produced by KCl, and
survival from an average lethal dose took place.
Source:
Norsk Hydro ASA
Reliability: (2) reliable with restrictions
Flag:
non confidential
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