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Poster Sessions
118
880. Quantitative Assessment of Emphysema with Dissolved-Phase & Gas-Phase Hyperpolarized 129 Xe MRI in Mice
Hirohiko Imai 1 , Atsuomi Kimura 1 , Satoshi Iguchi 1 , Hideaki Fujiwara 1
1 Department of Medical Physics & Engineering, Division of Health Sciences, Graduate School of Medicine, Osaka University, Suita,
Osaka, Japan
881. Regional Ventilation Mapping of the Rat Lung using Hyperpolarized 3 He & 129 Xe Magnetic Resonance Imaging
Marcus John Couch 1,2 , Alexei V. Ouriadov 1 , Giles E. Santyr 1,3
1 Imaging Research Laboratories, Robarts Research Institute, The University of Western Ontario, London, ON, Canada; 2 Department
of Physics & Astronomy, the University of Western Ontario, London, ON, Canada; 3 Department of Medical Biophysics, The
University of Western Ontario, London, ON, Canada
882. Quantifying Pulmonary Gas Transport Efficiency using Hyperpolarized Xenon-129
Kai Ruppert 1 , Jaime F. Mata 1 , Isabel M. Dregely 2 , Talissa A. Altes 1 , G. Wilson Miller 1 , Stephen Ketel 3 , Jeff Ketel 3 ,
Iulian C. Ruse 2,3 , F. William Hersman 2,3 , John P. Mugler III 1
1 University of Virginia, Charlottesville, VA, United States; 2 University of New Hampshire, Durham, NH, United States; 3 Xemed
LLC, Durham, NH, United States
883. 3D Imaging of Pulmonary Ventilation & Perfusion in Rats using Hyperpolarized 129 Xe
Zackary I. Cleveland 1 , Harald E. Moller 1,2 , Laurence W. Hedlund 1 , John Nouls 1 , Matthew Freeman 1,3 , Yi Qi 1 , Bastiaan
Driehuys 1
1 Center for In Vivo Microscopy, Duke University Medical Center, Durham, NC, United States; 2 Max Planck Institute for Human
Cognitive & Brain Sciences, Leipzig, Germany; 3 Graduate Program in Medical Physics, Duke University, Durham, United States
884. Improved Separation & Quantification of Xe-129 Dissolved-Phase Resonances in the Lung
Jaime Mata 1 , Kai Ruppert 1 , Peter Sylvester 1 , Isabel Dregely 2 , Talissa Altes 1 , Iulian Ruset 2 , William Hersman 2 , Grady
Miller 1 , Steve Ketel 2 , Jeff Ketel 2 , John Mugler III 1
1 Radiology, University of Virginia, Charlottesville, VA, United States; 2 Xemed, LLC, Durham, NH, United States
885. Measurement of 129 Xe Gas Apparent Diffusion Coefficient Anisotropy in an Elastase-Instilled Rat Model of
Emphysema
Mathieu Boudreau 1,2 , Xiaojun Xu 3 , William Dominguez-Viqueira 4 , Giles Santyr 1,5
1 Imaging Research Laboratories, John. P. Robarts Research Institute, London, Ontario, Canada; 2 Dept. of Physics & Astronomy,
University of Western Ontario, London, Ontario, Canada; 3 University of Sheffield, Sheffield, United Kingdom; 4 Imaging Research,
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 5 Dept. of Medical Biophysics, University of Western Ontario,
London, Ontario, Canada
886. Hyperpolarized 129 Xe Gas & Dissolved Phase Lung Imaging using IDEAL
Alexei V. Ouriadov 1 , Matthew Fox 2,3 , Lanette Friesen-Waldner 4 , Charles McKenzie 4,5 , Giles Santy 4
1 Robarts Research Institute, The University of Western Ontario , London, Ontario, Canada; 2 Robarts Research Institute, The
University of Western Ontario, London, Ontario, Canada; 3 The Department of Physics, Tthe University of Western Ontario; 4 The
Department of Medical Biophysics, The University of Western Ontario; 5 Biomedical Engineering Program, The University of Western
Ontario
887. Recovery & Purification of 3 He Gas from Pulmonary MRI
Sean Alexander Lourette 1 , Allen W. Che 2 , Jason C. Woods 1,2 , Mark S. Conradi 1,2
1 Physics, Washington University, St. Louis, MO, United States; 2 Radiology, Washington University, St. Louis, MO, United States
888. Xenon Hyperpolarized by the Dissolution-DNP Method
Jan Henrik Ardenkjaer-Larsen 1 , Haukur Johannesson 1 , Jan Wolber 2 , Nick Kuzma 3 , Rahim Rizi 3
1 GE Healthcare, Broendby, Denmark; 2 GE Healthcare, United Kingdom; 3 University of Pennsylvania, United States
889. Enhancement of 129 Xe Polarisation by Off-Resonant Optical Pumping
Steven Richard Parnell 1 , Martin H. Deppe 1 , Juan Parra-Robles 1 , Jim M. Wild 1
1 Academic Radiology, University of Sheffield, Sheffield, South Yorkshire, United Kingdom
890. Spectrally Narrowed 1.5 KW Optical Pumping Laser for Large-Scale SEOP Production of Hyperpolarized
Gases
F. W. Hersman 1,2 , Jan H. Distelbrink 2 , Jeff Ketel 2 , David Watt 2 , Stephen Ketel 2 , Walter Porter 2 , Steve Bryn 2 , Aaron
Hope 2 , Iulian Constantin Ruset 2
1 Department of Physics, University of New Hampshire, Durham, NH, United States; 2 Xemed LLC, Durham, NH, United States
891. Hyperpolarized Helium Measurements of P A O 2 Correlate with Neutrophil Inflammation in the Rat Bleomycin
Model
Puttisarn Mongkolwisetwara 1 , Evguenia Borissova Arguiri 2 , Kiarash Emami 1 , Yi Xin 1 , Nicholas N. Kuzma 1 , Stephen J.
Kadlecek 1 , Yinan Xu 1 , Harilla Profka 1 , Melpo Christofidou-Solomidou 2 , Milton D Rossman 2 , Masaru Ishii 3 , Rahim R.
Rizi