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<strong>Poster</strong> Sessions<br />
Alan Bainbridge 1 , Stuart Faulkner 2 , Dorottya Kelen 2 , Manigandan Chandrasekaran 2 , David Price 1 , David L. Thomas 3 ,<br />
Ernest B. Cady 1 , Nicola J. Robertson 2 , Xavier Golay 3<br />
1 Medical Physics & Bioengineering, UCLH NHS Foundation Trust, London, United Kingdom; 2 Institute for Women’s Health, UCL,<br />
London, United Kingdom; 3 Institute of Neurology, UCL, United Kingdom<br />
2246. In Vivo Measurements of Cerebral Ascorbate Increases After Systemic Ascorbate Infusion<br />
In-Young Choi 1,2 , Wen-Tung Wang 1 , Joanne Marcario 1 , Mark Levine 3 , Phil Lee 1,4<br />
1 Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, United States; 2 Department of Neurology,<br />
University of Kansas Medical Center, Kansas City, KS, United States; 3 Molecular & Clinical Nutrition Section, National Institute of<br />
Health, Be<strong>the</strong>sda, MD, United States; 4 Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, KS,<br />
United States<br />
2247. Isoflurane Elevates Brain Lactate in a Dose-Dependent Manner: A Localized 1 H MRS Study of Mouse Brain In<br />
Vivo<br />
Susann Boretius 1 , Roland Tammer 1,2 , Thomas Michaelis 1 , Jens Frahm 1<br />
1 Biomedizinische NMR Forschungs GmbH, Max-Planck-Institut fuer biophysikalische Chemie, Göttingen, Germany; 2 DFG Research<br />
Center for Molecular Biology of <strong>the</strong> Brain (CMPB), Göttingen, Germany<br />
2248. Effect of Nicotine on Glutamatergic & GABAergic Neurotransmission in Developing Brain<br />
Anant Bahadur Patel 1 , Mohammad Shameem 1<br />
1 NMR Microimaging & Spectroscopy, Centre for Cellular & Molecular Biology, Hyderabad, Andhra Pradesh, India<br />
2249.<br />
1 H-MRS Profiling of <strong>the</strong> Developing Rat Brain<br />
Serguei Liachenko 1 , Jaivijay Ramu 1<br />
1 FDA / NCTR, Jefferson, AR, United States<br />
2250. Acute Restraint Stress-Induced Change in Glutamate Neurotransmission in Rat Brain: An In Vivo 1 H-MRS<br />
Study<br />
Sang-Young Kim 1 , Eun-Ju Jang 2 , Kwan-Soo Hong 2 , Chul-Hyun Lee 2 , Do-Wan Lee 1 , Chi-Bong Choi 3 , Bo-Young Choe 1<br />
1 Department of Biomedical Engineering, The Catholic University of Korea, Seoul, Korea, Republic of; 2 The Korea Basic Science<br />
Institute, Korea, Republic of; 3 Department of Radiology, Kyunghee University Medical Center, Korea, Republic of<br />
2251. Neurochemical Changes in Olfactory System & Hippocampus Regions of Tau Transgenic Mice using 1 H MRS<br />
Jieun Kim 1 , In-Young Choi 1,2 , Karen Duff 3 , Phil Lee 1,4<br />
1 Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, United States; 2 Department of Neurology,<br />
University of Kansas Medical Center, Kansas City, KS, United States; 3 Department of Integrative Neuroscience, Columbia University<br />
Medical Center, New York, NY, United States; 4 Department of Molecular & Integrative Physiology, University of Kansas Medical<br />
Center, Kansas City, KS, United States<br />
2252. Measurement of Metabolic Rates in Rat Olfactory Bulb by 1 H & 1 H-[ 13 C] NMR In Vivo<br />
Golam M. I. Chowdhury 1 , Graeme F. Mason 1 , Kevin L. Behar 1 , Douglas L. Rothman 1 , Robin A. de Graaf 1<br />
1 MRRC, Yale University School of Medicine, New Haven, CT, United States<br />
2253. In Vivo Assessment of Neuronal Metabolic Fluxes in Mouse Brain by 1 H-[ 13 C] NMR Spectroscopy<br />
Lijing Xin 1 , Hongxia Lei 2 , Bernard Lanz 2 , Rolf Gruetter 1,2<br />
1 Department of Radiology, University of Lausanne, Lausanne, Vaud, Switzerland; 2 Laboratory of functional & metabolic imaging,<br />
École Polytechnique Fédérale de Lausanne, Lausanne, Vaud, Switzerland<br />
2254. Simultaneous Dection of Metabolism of [2- 13 C]lactate & Uniformly Labeled Glucose in <strong>the</strong> Brain using In Vivo<br />
13 C MRS<br />
Yun Xiang 1 , Jun Shen 1<br />
1 Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Be<strong>the</strong>sda, MD, United States<br />
2255. Non-Invasive Monitoring of Antioxidant Prodrug Metabolism in Rat Brain by In Vivo 13 C MRS<br />
Peter Edward Thelwall 1 , Daniel Clark 2 , Susan M. Ludeman 3 , James B. Springer 4 , Michael A. D'Alessandro 3 , Nicholas<br />
E. Simpson 2 , Roxana Pourdeyhimi 5 , C. Bryce Johnson 5 , Stephanie D. Teeter 5 , Stephen J. Blackband 2 , Michael P.<br />
Gamcsik 5<br />
1 Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, Tyne & Wear, United Kingdom; 2 University of<br />
Florida; 3 Albany College of Pharmacy & Health Sciences; 4 Duke University Medical Centre; 5 Joint Department of Biomedical<br />
Engineering, University of North Carolina / NC State University<br />
2256. Direct Assessment of Increased Pyruvate Carboxylase in <strong>the</strong> Hyperammonemic Brain using 13 C MRS<br />
Bernard Lanz 1 , Cristina Cudalbu 1 , João Miguel Duarte 1 , Rolf Gruetter 1,2<br />
1 Laboratory for Functional & Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; 2 Department of<br />
Radiology, Universities of Lausanne & Geneva, Lausanne & Geneva, Switzerland<br />
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