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Poster Sessions
901. 3D 3 He & 1 H MR Imaging of Regional Pulmonary Injury Induced by Ozone
John Nouls 1,2 , Erin Potts 3 , W Michael Foster 3 , Bastiaan Driehuys 1,2
1 Department of Radiology, Duke University, Durham, NC, United States; 2 Center for In Vivo Microscopy, Duke University, Durham,
NC, United States; 3 Department of Pulmonary and Critical Care Medicine, Duke University
902. Signal Distribution in Dissolved 129 Xe MR Images of Healthy Subjects & Subjects with Chronic Obstructive
Pulmonary Disease
Zackary I. Cleveland 1 , S. Sivaram Kaushik 1,2 , Gary P. Cofer 1 , John Nouls 1 , Monica Kraft 3 , Jan Wolber 4 , H. Page
McAdams 5 , Bastiaan Driehuys 1
1 Center for In Vivo Microscopy, Duke University Medical Center, Durham, NC, United States; 2 Department of Biomedical
Engineering, Duke University, Durham, NC, United States; 3 Department of Medicine, Duke University Medical Center, Durham, NC,
United States; 4 GE Healthcare, Amersham, United Kingdom; 5 Department of Radiology, Duke University Medical Center, Durham,
NC, United States
903. Towards Very High Net Acceleration Factors in Hyperpolarized 3 He Human Lung Parallel Imaging using
SPIRiT
Martin H. Deppe 1 , Salma Ajraoui 1 , Jim M. Wild 1
1 Academic Unit of Radiology, University of Sheffield, Sheffield, South Yorkshire, United Kingdom
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904. Helium-3 Magnetic Resonance Imaging of Treatment Response in Exercise Induced Bronchoconstriction
Stanley John Kruger 1 , David Niles 1 , Grace Parraga 2 , Sean Fain 1 , Bernard Dardzinski 3 , Marcella Ruddy 3 , Amy
Harman 3 , Stephen Choy 2 , Scott Nagle 4 , Christopher Francois 4 , David G. McCormack 2 , Nizar Jarjour 5
1 Medical Physics, University of Wisconsin, Madison, WI, United States; 2 Robarts Imaging Institution, University of Western Ontario,
London, ON, Canada; 3 Merck Research Labs, West Point, PA, United States; 4 Radiology, University of Wisconsin, Madison, WI,
United States; 5 Medicine & Public Health, University of Wisconsin, Madison, WI, United States
905. Test-Retest & Inter-Reader Reliability of Hyperpolarized Helium-3 MRI in Patients with Exercise-Induced
Bronchoconstriction
David Joseph Niles 1 , Stanley J. Kruger 1 , Grace Parraga 2,3 , Bernard Dardzinski 4 , Marcella Ruddy 4 , Nizar N. Jarjour 5 ,
David G. McCormack 6 , Amy Harman 4 , Sean B. Fain 1 , 7
1 Medical Physics, University of Wisconsin, Madison, WI, United States; 2 Imaging Research Laboratories, Robarts Research Institute,
University of Western Ontario, London, ON, Canada; 3 Medical Biophysics, University of Western Ontario, London, ON, Canada;
4 Merck Research Laboratories, West Point, PA, United States; 5 Pediatrics, University of Wisconsin, Madison, WI, United States;
6 Division of Respirology, Department of Medicine, University of Western Ontario, London, ON, Canada; 7 Radiology, University of
Wisconsin, Madison, WI, United States
906. Evaluating Bronchodilator Effects in Chronic Obstructive Pulmonary Disease using Hyperpolarized Helium-3
Magnetic Resonance Imaging
Miranda Kirby 1,2 , Roya Etemad-Rezai 3 , David G. McCormack 4 , Grace Parraga 1,5
1 Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada; 2 Medical Biophysics, the University of
Western Ontario, London, Ontario, Canada; 3 Department of Medical Imaging, the University of Western Ontario, London, Ontario,
Canada; 4 Division of Respirology, Department of Medicine, the University of Western Ontario, London, Ontario, Canada; 5 Graduate
Program in Biomedical Engineering, the University of Western Ontario, London , Ontario, Canada
907. Evaluation of Short Term Reproducibility of Hyperpolarized Helium-3 Magnetic Resonance Imaging of Adult
Cystic Fibrosis using a Semi-Automated Segmentation Tool
Sarah Svenningsen 1,2 , Miranda Kirby 1,2 , Hassaan Ahmed 1,2 , Nigel Paterson 3 , Grace Parraga 1,4
1 Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada; 2 Department of Medical Biophysics, The
University of Western Ontario, London, Ontario, Canada; 3 Division of Respirology, Department of Medicine, the University of
Western Ontario, London, Ontario, Canada; 4 Graduate Program in Biomedical Engineering, The University of Western Ontario,
London, Ontario, Canada
908. Quantitative Evaluation of Ventilation Dynamics in Asthma During Methacholine Challenge using
Hyperpolarized 3 He Magnetic Resonance Imaging
Stephen Costella 1,2 , Andrew Wheatley 1 , David McCormack 3 , Grace Parraga 1,2
1 Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada; 2 Graduate Program in Biomedical
Engineering, University of Western Ontario, London, Ontario, Canada; 3 Medicine, Division of Respirology, University of Western
Ontario, London, Ontario, Canada
909. Gas Diffusion Image Reduction Metric with Improved Sensitivity to Heterogeneous Lung Disease
Ahsan Samiee 1 , Stephen J. Kadlecek 2 , Kiarash Emami 2 , Yinan Xu 2 , Hooman Hamedani 3 , Yi Xin 2 , Puttisarn
Mongkolwisetwara 2 , Nicholas N. Kuzma 2 , Peter Magnusson 4 , Lise Vejby Søgaard 4 , Sandra Diaz 5 , Wilson Miller 6 ,
Milton D. Rossman 7 , Masaru Ishii 8 , Rahim R. Rizi 2
1 Mechanical & Aerospace Engineering, University of California, San Diego, San Diego, CA, United States; 2 Radiology, University of
Pennsylvania, Philadelphia, PA, United States; 3 Radiology, University of Pennsylvania, Philadelphia, United States; 4 Danish Research
Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark; 5 Department of Clinical Sciences,