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Poster Sessions
2148. Early Metabolic Biomarkers Identifying Permanent Stroke in Mouse Brain using 1 H MRS
Hongxia Lei 1,2 , Carole Berthet 3 , Lorenz Hirt 3 , Rolf Gruetter 1,4
1 Laboratory of Functional & Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; 2 Radiology,
Univeristy of Lausanne, Switzerland; 3 Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois, Switzerland; 4 Radiology,
University of Geneva, Geneva, Switzerland
2149. Early Post-Ischemic Neuroprotective Mechanisms: A MR Spectroscopic Imaging Study on PPARβ-Deficient
Mice
Mélanie Craveiro 1 , Laure Quignodon 2 , Carole Berthet 3 , Matthew Hall 2 , Cristina Cudalbu 1 , Lorenz Hirt 3 , Béatrice
Desvergne 2 , Rolf Gruetter 1,4
1 Laboratory for Functional & Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; 2 Center for
Integrative Genomics, University of Lausanne, Lausanne, Switzerland; 3 Department of Neurology, Centre Hospitalier Universitaire
Vaudois, Lausanne, Switzerland; 4 Departments of Radiology, Universities of Lausanne & Geneva, Switzerland
2150. Ischemic Brain Damage & Loss of Ion Homeostasis During Focal Ischemia
Fernando Emilio Boada 1 , Edwin Nemoto 2 , Yongxian Qian 3 , Costin Tanase 3 , Charles Jungreis 4 , Jonathan Weimer,
Vincent Lee
1 Radiology & Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States; 2 Neurosurgery, University of New Mexico,
Albuquerque, NM, United States; 3 Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 4 Radiology, Temple University,
Philadelphia, PA, United States
2151. The Effect of Amyloid on Infarct Size in a Rat Model
Simona Nikolova 1 , Zareen Amtul 2 , David Cechetto 2 , Ting-Yim Lee 3 , Vladimir Hachinski 4 , Robert Bartha 2,3
1 Robarts Research Institute, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada;
2 Department of Anatomy, University of Western Ontario, London, ON, Canada; 3 Robarts Research Institute, Schulich School of
Medicine & Dentistry, University of Western Ontario, London, ON, Canada; 4 London Health Sciences Centre, London, ON, Canada
2152. The Importance of Reperfusion Injury in Antenatal Hypoxia-Ischemia: Novel Fetal MRI Diagnostic Parameters
& Novel Antioxidant Therapy
Alexander Drobyshevsky 1 , Xinhai Ji 1 , Matthew Derrick 1 , Lei Yu 1 , Ines Batinic-Haberle 2 , Sidhartha Tan 1
1 Pediatrics, Evanston Northshore Healthcare, Evanston, IL, United States; 2 Radiation Oncology, Duke University Medical Center,
Durham, NC, United States
2153. MRI Evaluation of Carotid Morphology & Function in a Rabbit Constriction Model of Atherosclerosis: A
Feasibility Study
Steve J. Sawiak 1 , Valentina Taviani 2 , Victoria E. Young 2 , Joe L. Bird 3 , Hugh K. Richards 4 , Andrew J. Patterson 2 ,
Martin J. Graves 2 , Adrian T. Carpenter 1 , Jonathan H. Gillard 2
1 Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom; 2 Department of Radiology,
University of Cambridge, Cambridge, United Kingdom; 3 Clinical Pharmacology Unit, University of Cambridge, Cambridge, United
Kingdom; 4 Department of Anesthesia, University of Cambridge, Cambridge, United Kingdom
2154. T 2 *-Weighted Signal Change of Oxygen Challenge as a Potential Better Penumbra Estimation—A Transient
Occlusion Study
Fang Du 1 , Qiang Shen 1,2 , Shiliang Huang 1 , Timothy Q. Duong 1,2
1 Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States;
2 Ophthalmology/Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
2155. Incorporating ADC Temporal Profiles in Acute Stroke to Predict Ischemic Tissue Fate
Qiang Shen 1,2 , Virendra Desai 1 , Timothy Q. Duong 1,2
1 Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States;
2 Ophthalmology/Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
2156. In Vivo Kurtosis Imaging in Murine Cerebral Ischemia
Andreas Lemke 1 , Saskia Grudzenski 2 , Jörg Döpfert 1 , Frederik Bernd Laun 3 , Tristan Kuder 3 , Marc Fatar 2 , Lothar Rudi
Schad 1
1 Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany; 2 Experimental Neurology, Heidelberg
University, Mannheim, Germany; 3 Department of Medical Physics in Radiology, German Cancer Research Center, Heidelberg,
Germany
Multiple Sclerosis
Exhibition Hall Monday 14:00-16:00
236
2157. Baseline T 2 MRI Texture Predicts Visual Recovery in Patients with Acute Optic Neuritis
Yunyan Zhang 1 , Fiona Costello 1 , James N. Scott, Luanne M. Metz 1