<strong>Poster</strong> Sessions 2519. Brain Bioenergetic Changes Caused by Transcranial Direct Current Stimulation; a 31 P MRS Study Caroline Rae 1 , Vincent Lee 2 , Colleen Loo 3 , Roger Ordidge 4 1 Neuroscience Research Australia, Randwick, NSW, Australia; 2 School of Medical Sciences, <strong>the</strong> University of New South Wales, NSW, Australia; 3 School of Psychiatry, <strong>the</strong> University of New South Wales, Australia; 4 Dept of Medical Physics, University College London, United Kingdom 2520. Increased Striatal Iron Accumulation in Methamphetamine Users Yosef A. Berlow 1,2 , David L. Lahna 3,4 , Daniel L. Schwartz 3,4 , Alex D. Mitchell 5 , Alexander A. Stevens 2,3 , William D. Rooney 1,2 , William F. Hoffman 3,5 1 Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, United States; 2 Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, United States; 3 Department of Psychiatry, Oregon Health & Science University, Portland, OR, United States; 4 Methamphetamine Abuse Research Center, Portland Veterans Affairs Medical Center, Portland, OR, United States; 5 Mental Health & Clinical Neurosciences Division, Portland Veterans Affairs Medical Center, Portland, OR, United States 2521. MRI & Histological Evidence for <strong>the</strong> Blockade of Cuprizone-Induced Demyelination in C 57 /B l6 Mice by Quetiapine Prasant Chandran 1 , Jaymin Upadhyay 1 , Stella Markosyan 2 , Andrew Lisowski 3 , Wayne Buck 3 , Gerard B. Fox 1 , Mark Day 1 , Feng Luo 1 1 Translational Imaging & Biochemistry, Abbott Laboratories, Abbott Park, IL, United States; 2 Neuroscience Discovery, Abbott Laboratories, Abbott Park, IL, United States; 3 Cellular & Molecular Exploratory Toxicology, Abbott Laboratories, Abbott Park, IL, United States 2522. Intra-Orbital Distance as a Record of Social Brain Dysmorphology in Autism. Charlton Cheung 1 , Kevin Yu 1 , Antonia Yam 2 , Valencia Myint 3 , Yan Fung Yee 4 , Siew Chua 5,6 , Grainne Mary McAlonan 5,7 1 Psychiatry, University of Hong Kong, Pokfulam, Hong Kong; 2 Neuroscience, University of Bristol, United Kingdom; 3 Psychology, University of Cardiff, United Kingdom; 4 University of Harvard, United States; 5 Psychiatry, University of Hong Kong, Hong Kong, Hong Kong; 6 State Key Laboratory for Brain & Cognitive Sciences; 7 Key State Laboratory for Brain & Cognitive Sciences 2523. The Siena/FSL Whole Brain Atrophy Measurement Algorithm May Require Substantially Larger Group Sizes at 3T Than 1.5T for Alzheimer's Disease Keith S. Cover 1 , Ronald A. van Schijndel 2 , Bob W. van Dijk 3 , Alberto Redolfi 4 , Dirk L. Knol 5 , Giovanni B. Frisoni 4 , Frederik Barkhof 2 , Hugo Vrenken 2,6 1 Physics & Medical Technology, VU University Medical Center, Amsterdam, North Holland, Ne<strong>the</strong>rlands; 2 Department of Radiology, VU University Medical Center, Amsterdam, Ne<strong>the</strong>rlands; 3 Department of Physics & Medical Technology, VU University Medical Center, Amsterdam, Ne<strong>the</strong>rlands; 4 Laboratory of Epidemiology & Neuroimaging, IRCCS San Giovanni di Dio Fatebenefratelli, Brescia, Italy; 5 Department of Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, Ne<strong>the</strong>rlands; 6 MS Center Amsterdam & Alzheimer Center, VU University Medical Center, Amsterdam, Ne<strong>the</strong>rlands 2524. Dynamic Response Inhibition Network in Heroin Addicts Brain: Evidence from Functional Neuroimaging with GO/Go-Nogo Task Zheng Yang 1 , Chunming Xie 2,3 , Yongcong Shao 1 , Liping Fu 1 , Gang Chen 2 , Wenjun Li 2 , Joseph Goveas 4 , Guangyu Chen 2 , Enmao Ye 1 , Lin Ma 5 , Shi-Jiang Li 2 1 Beijing Institute of Basic Medical Science, Beijing, China, People's Republic of; 2 Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 3 Neurology, School of Clinical Medicine, Sou<strong>the</strong>ast University, Nanjing, Jiangsu, China, People's Republic of; 4 Psychiatry & Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI, United States; 5 The PLA General Hospital, Beijing, China, People's Republic of 2525. Decoupling of Intrinsic Insula Subregional Connectivity was Associated with Episodic Memory Decline in Amnestic Mild Cognitive Impairment Chunming Xie 1,2 , Feng Bai 1,3 , Xiaobin Zhang 1 , Hui Yu 1 , Yongmei Shi 3 , Yonggui Yuan 4 , Alexander Cohen 2 , Joseph Goveas 5 , Gang Chen 2 , Wenjun Li 2 , Guangyu Chen 2 , Zheng Yang 6 , Zhijun Zhang 3,4 , Shi-Jiang Li 2 1 Neurology, School of Clinical Medicine, Sou<strong>the</strong>ast University, Nanjing, Jiangsu, China, People's Republic of; 2 Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 3 Neurology, Affiliated Zhongda Hospital of Sou<strong>the</strong>ast University, Nanjing, Jiangsu, China, People's Republic of; 4 Institute of Neuropsychiatry of Sou<strong>the</strong>ast University, Nanjing, Jiangsu, China, People's Republic of; 5 Psychiatry & Behavioral Medicine, Medical College of Wisconsin, Milwaukee, WI, United States; 6 Beijing Institute of Basic Medical Science, Beijing, China, People's Republic of 2526. In Vivo MRI Detection of HDAC 5 During Chronic Amphetamine Stimuli Christina H. Liu 1 , Jinsheng Yang 1 , Jia Q. Ren 1 , Charng-Ming Liu 1 , Huifang Wang 1 , Philip K. Liu 1 1 Radiology, Massachusetts General Hospital, Charlestown, MA, United States 272 2527. Multimodal Assessment of Medial Temporal Lobe Function in Schizophrenia Laura M. Rowland 1 , Elena A. Spieker 1 , Kimberly Kontson 1 , Kathryn W. Buchanan 1 , Peter B. Barker 2 , Henry H. Holcomb 1,3
<strong>Poster</strong> Sessions 1 Psychiatry, MPRC, University of Maryland School of Medicine, Baltimore, MD, United States; 2 Russell H. Morgan Department of Radiology & Radiological Sciences, Johns Hopkins University School of Medicine; 3 Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, United States 2528. A 1 H-MRS Study of <strong>the</strong> Auditory Cortex in Persons with Autism Spectrum Disorder (ASD) Mark Steven Brown 1 , Katie Youngpeter 2 , Debra Singel 3 , Susan Hepburn 2 , Don C. Rojas 2 1 Radiology, University of Colorado Denver, Aurora, CO, United States; 2 Psychiatry, University of Colorado Denver, Aurora, CO, United States; 3 Brain Imaging Center, University of Colorado Denver, Aurora, CO, United States 2529. Alteration of Brain Metabolites in Patients with Type 2 Diabetes &/or Major Depression Measured by Proton MR Spectroscopy at 3T Shaolin Yang 1,2 , Olusola Ajilore 1 , Minjie Wu 3 , Melissa Lamar 1 , Anand Kumar 1 1 Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, United States; 2 Department of Radiology, University of Illinois at Chicago, Chicago, IL, United States; 3 Department of Neuology, Northwestern University, Chicago, IL, United States 2530. Glutamate Correlations between <strong>the</strong> Anterior Cingulate & Cerebellar Vermis Kevin Wayne Waddell 1 , Subechhya Pradhan 2 , Malcolm Avison 1 , John Gore 3 1 Radiology, Vanderbilt, Nashville, TN, United States; 2 Physics, Vanderbilt University, Nashville, TN, United States; 3 Radiology, Vanderbilt University, Nashville, TN, United States 2531. Brain-Derived Neurotrophic Factor (BDNF) Genotype is Associated with Frontal Gray & White Matter Volume Recovery in Abstinent Alcohol Dependent Individuals Anderson Mon 1 , Timothy C. Durazzo 1 , Kent Hutchison 2 , Dieter J. Meyerhoff 1 1 Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States; 2 Psychology, <strong>the</strong> MIND Institute, University of New Mexico, Albuquerque, NM, United States 2532. Quantification of Cerebral Gene Activities In Vivo by Gene-Targeting MRI Christina Liu 1 , Jinsheng Yang 1 , Jia Q Ren 1 , Charng-Ming Liu 1 , Philip Liu 1 1 Radiology, Massachusetts General Hospital, Charlestown, MA, United States 2533. Anterior Cingulate Metabolic Abnormalities in Late-Life Major Depression Olusola Ajilore 1 , Aifeng Zhang 1 , Rajakumar Nagarajan 2 , Albert Thomas 2 , Anand Kumar 1 1 Psychiatry, University of Illinois-Chicago, Chicago, IL, United States; 2 Unversity of California, Los Angeles 2534. MEG Auditory Evoked Gamma Phase Locking Correlates with 1 H-MRS Determined Temporal Lobe GABA Levels Mark Steven Brown 1 , Peter Teale 2 , Dan Collins 2 , Bryce Pasko 2 , Debra Singel 3 , Don C. Rojas 2 , Martin Reite 2 1 Radiology, University of Colorado Denver, Aurora, CO, United States; 2 Psychiatry, University of Colorado Denver, Aurora, CO, United States; 3 Brain Imaging Center, University of Colorado Denver, Aurora, CO, United States 2535. Effects of DTNBP 1 (Dysbindin) Gene Variants on Hippocampal Glutamate Concentration Determined by MRS at 3T Florian Schubert 1 , Frank Seifert 1 , Christoph Wirth 2 , Andreas Klär 2 , Thomas Sander 2 , Jürgen Gallinat 2 1 Physikalisch-Technische Bundesanstalt, Berlin, Germany; 2 Psychiatry, Charité University Medicine, Berlin, Germany 2536. Effect of Psychostimulants on Basal Ganglia Structures in Young ADHD Children Laura Cyckowski 1 , Carolyn McIlree 2 , Brian Avants 3 , Philip Cook 3 , Melissa Narain 4 , Ruth Milanaik 5 , Li Kan 5 , Jeffrey Newcorn 6 , Josephine Elia, James Gee 3 , Andrew Adesman 7 , Manzar Ashtari 1 Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, United States; 2 University of Vermont College of Medicine, Burlington, VT, United States; 3 University of Pennsylvania, Philadelphia, PA, United States; 4 Zucker Hillside Hospital, North Shore LIJ Health Systems, Glen Oaks, NY, United States; 5 Schneider Children's Hospital, New Hyde Park, NY, United States; 6 Mount Sinai School of Medicine, New York, NY, United States; 7 Schneider Children's Hospital, New Hyde Park, PA, United States 2537. Voxel-Based Morphometry in Assessing a Rat Model of Impulsivity: Agreement with Targeted Western Blot Analysis Stephen John Sawiak 1,2 , Daniele Caprioli 3 , E. Merlo 3 , D. Theobald 3 , B. J. Everitt 3 , T. W. Robbins 2.3 , T. A. Carpenter 1 , Jeffrey W. Dalley 3,4 1 Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, UK, United Kingdom; 2 Behavioural & Clinical Neurosciences Institute, University of Cambridge, Cambridge, United Kingdom; 3 Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom; 4 Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom 2538. Probing Axon- & Myelin-Specific White Matter Abnormalities in Schizophrenia using MRI/MRS Dost Ongur 1 , Fei Du 1 , Bruce M. Cohen, Alissa Cooper 1 , Scott Lukas, Perry F. Renshaw 2 1 Psychotic Disorders Division, McLean Hospital/Harvard Medical School, Belmont, MA, United States; 2 Psychiatry, University of Utah, Salt Lake City, UT, United States 273
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