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<strong>Poster</strong> Sessions<br />
248<br />
2267. MRI Reveals Differences in Neuroanatomy of Mouse Models of NPC Disease<br />
John Totenhagen 1 , Eriko Yoshimaru 1 , Ivan Borbon 2 , Christy Howison 3 , Robert Erickson 2 , Theodore Trouard 1<br />
1 Biomedical Engineering, University of Arizona, Tucson, AZ, United States; 2 Pediatrics, University of Arizona, Tucson, AZ, United<br />
States; 3 Arizona Research Laboratories, University of Arizona, Tucson, AZ, United States<br />
2268. Reduction of Contralateral White Matter Volume After Experimental Focal Epilepsy & Hemispherectomy in<br />
Rats<br />
Willem M. Otte 1,2 , Kajo van Der Marel 2 , Kees P. J. Braun 1 , Rick M. Dijkhuizen 2<br />
1 Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, Ne<strong>the</strong>rlands; 2 Image Sciences Institute,<br />
University Medical Center Utrecht, Utrecht, Ne<strong>the</strong>rlands<br />
2269. Long Term Observations on Status-Epilepticus Induced Neurodegeneration: A 7 Tesla MR Study in a Rat<br />
Model<br />
Martin Meier 1 , Jens P. Bankstahl 2 , Marion Bankstahl 2 , Xiao-Qi Ding 3<br />
1 Small Animal Imaging Facility, Hannover Medical School, Hannover, Germany; 2 Institute for Pharmacology, Toxicology &<br />
Pharmacy, University of Veterinary Medicine, Hannover, Germany; 3 Institute of Diagnostic & Interventional Neuroradiology,<br />
Hannover Medical School, Hannover, Germany<br />
2270. Metabolic & Morphological Characterization of <strong>the</strong> Mecp2-308 Truncated Mouse Model of Rett Syndrome:<br />
Effects of a Treatment Activating Rho GTPases<br />
Rossella Canese 1 , Bianca De Filippis 1 , Carla Fiorentini 2 , Alessia Fabbri 2 , Paola Porcari 1 , Laura Ricceri 1 , Giovanni<br />
Laviola 1<br />
1 Cell Biology & Neurosciences Dept., Istituto Superiore di Sanità, Rome, RM, Italy; 2 Therapeutic Research & Medicine Evaluation<br />
Dept., Istituto Superiore di Sanità, Rome, RM, Italy<br />
2271. Molecular Imaging of Inflammation in a Cerebrovascular Aneurysm Model.<br />
Alexei A. Bogdanov 1 , Mat<strong>the</strong>w J. Gounis, Ronn Walvick, Ajay K. Wakhloo<br />
1 Radiology, UMASS Medical School, Worcester, MA, United States<br />
2272. Reduced Functional Connectivity in Normal Aging in Non-Human Primates<br />
Alexandre Coimbra 1 , Dai Feng 2 , Marie Holahan 1 , Jacquelynn Cook 1 , Donald Williams 1 , Richard Baumgartner 2<br />
1 Imaging, Merck & Co, Inc, West Point, PA, United States; 2 Biometrics, Merck & Co, Inc, Rahway, NJ, United States<br />
2273. Characterization of Lesions & Regional Brain Tissue of ArcAbeta Mice Based on Magnetic Susceptibility<br />
Andreas Deistung 1 , Jan Klohs 2 , Ferdinand Schweser 1 , Joanes Grandjean 2 , Marco Dominietto 2 , Conny Waschkies 2 ,<br />
Roger M. Nitsch 3 , Markus Rudin 2,4 , Jürgen R. Reichenbach 5<br />
1 Medical Physics Group, Department of Diagnostic & Interventional Radiology I, Jena University Hospital , Jena, Germany; 2 Institute<br />
for Biomedical Engineering, ETH & University of Zürich, Switzerland; 3 Division of Psychiatry Research, University of Zürich,<br />
Switzerland; 4 Institute of Pharmacology & Toxicology, University of Zürich , Switzerland; 5 Medical Physics Group, Department of<br />
Diagnostic & Interventional Radiology I, Jena University Hospital, Jena, Germany<br />
2274. Voxel-Based Morphometry Reveals Localised Cerebral Atrophy in a Mouse Lemur Model of Aging<br />
Stephen John Sawiak 1,2 , Marc Dhenain 3<br />
1 Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England, United Kingdom; 2 Behavioural & Clinical<br />
Neurosciences Institute, University of Cambridge, Cambridge, United Kingdom; 3 MIRCen, I2BM Institute of Biomedical Imaging,<br />
Fontenay aux Roses, France<br />
2275. Cortical Atrophy in Experimental Autoimmune Encephalomyelitis<br />
Allan J. MacKenzie-Graham 1 , Gilda A. Rinek 1 , Stefan M. Gold 2 , Andrew J. Frew 1 , Cynthia Aguilar 3 , David R. Lin 1 ,<br />
Elizabeth Umeda 1 , Rhonda R. Voskuhl 1 , Jeffry R. Alger 1<br />
1 University of California, Los Angeles, Los Angeles, CA, United States; 2 Universität Hamburg, Hamburg, Germany; 3 Indiana<br />
University of Pennsylvania, Indiana, PA, United States<br />
2276. Voxel-Based Morphometry using DARTEL in <strong>the</strong> Mouse Reveals Differential Impact of Early & Late Prenatal<br />
Inflammation on Adult Brain.<br />
Charlton Cheung 1 , Qi Li 2,3 , Edward X. Wu 2,4 , Grainne Mary McAlonan 5,6<br />
1 Psychiatry, University of Hong Kong, Pokfulam, Hong Kong; 2 University of Hong Kong, Hong Kong; 3 Centre for Reproduction,<br />
Development and Growth; 4 4Laboratory of Biomedical Imaging and Signal Processing; 5 University of Hong Kong, Hong Kong, Hong<br />
Kong; 6 State Key Laboratory for Brain and Cognitive Sciences<br />
2277. Axonal Damage Caused by Exposure of Axon Terminals to Amyloid Beta<br />
David Carrick 1 , Bruce Campbell 2 , Hsiao-Fang Liang 3 , Wei-Xing Shi 4 , Shu-Wei Sun 5<br />
1 Basic Science, School of Medicine, Loma Linda University, Loma Linda, CA, United States; 2 Clinical Laboratory Science, School of<br />
Allied Health, Loma Linda University, Loma Linda; 3 Biophysics & Bioengineering, Loma Linda University; 4 Pharmaceutical<br />
Sciences & Basic Sciences, Schools of Pharmacy & Medicine, Loma Linda University; 5 Biophysics & Bioengineering, Loma Linda<br />
University, Loma Linda, CA, United States
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