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Poster Sessions
1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Pulmonary Division, University of Pennsylvania,
Philadelphia, PA, United States; 3 Otolaryngology–Head & Neck Surgery, Johns Hopkins University, Baltimore, MD, United States
892. Quantitative Assessment of Chronic Exposure to Cigarette Smoke in Mouse Lungs by Hyperpolarized Gas MRI
Yi Xin 1 , Kiarash Emami 1 , Stephen J. Kadlecek 1 , Puttisarn Mongkolwisetwara 1 , Nicholas N. Kuzma 1 , Harilla Profka 1 ,
Yinan Xu 1 , Hooman Hamedani 1 , Benjamin M. Pullinger 1 , Rajat K. Ghosh 1 , Jennia N. Rajaei 1 , Stephen Pickup 1 , Masaru
Ishii 2 , Rahim R. Rizi 1
1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Otolaryngology–Head & Neck Surgery, Johns Hopkins
University, Baltimore, MD, United States
893. Non-Invasive Assessment of Pulmonary Developmental Deficiency in a Model of Transgenic Mice using
Hyperpolarized Gas Diffusion MRI
Amy Barulic 1 , Kiarash Emami 2 , Yi Xin 1 , Puttisarn Mongkolwisetwara 1 , Harilla Profka 1 , Nicholas N. Kuzma 1 , Jeanine
M. D'Armiento 3 , Takayuki Shiomi 4 , Stephen J. Kadlecek 1 , Yinan Xu 1 , Hooman Hamedani 1 , Benjamin Michael
Pullinger 1 , Rajat Ghosh 1 , Jennia Rajaei 1 , Stephen Pickup 1 , Masaru Ishii 5 , Rahim R. Rizi 1
1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Radiology, University of Pennsylvania, PA, PA, United
States; 3 Departments of Medicine & Surgery, Columbia University, New York, NY, United States; 4 Department of Molecular
Medicine, Columbia University, New York, NY, United States; 5 Otolaryngology–Head & Neck Surgery, Johns Hopkins University,
Baltimore, MD, United States
894. Imaging of Airway Remodeling in a Murine Model of Bronchial Hyper-Responsiveness using Hyperpolarized
Gas MRI
Kiarash Emami 1 , Jennia N. Rajaei 1 , Yi Xin 1 , Puttisarn Mongkolwisetwara 1 , Harilla Profka 1 , Stephen J. Kadlecek 1 ,
Hooman Hamedani 1 , Yinan Xu 1 , Amy Barulic 1 , Stephen Pickup 1 , Nicholas N. Kuzma 1 , Blerina Ducka 2 , Angela
Haczku 2 , Masaru Ishii 3 , Rahim R. Rizi 1
1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Pulmonary & Critical Care Division, University of
Pennsylvania Medical Center, Philadelphia, PA, United States; 3 Otolaryngology–Head & Neck Surgery, Johns Hopkins University,
Baltimore, MD, United States
895. Imaging Lung Microstructure in Mice with Hyperpolarized 3 He Diffusion MRI
Wei Wang 1,2 , Nguyet M. Nguyen 3 , Dmitriy A. Yablonskiy 1,2 , Alexander L. Sukstanskii 2 , Emir Osmanagic 2 , Richard A.
Pierce 3 , Mark S. Conradi 1,2 , Jason C. Woods 1,2
1 Physics, Washington University in St. Louis, St. Louis, MO, United States; 2 Radiology, Washington University in St. Louis, St.
Louis, MO, United States; 3 Internal Medicine, Washington University in St. Louis, St. Louis, MO, United States
896. Ventilation Strategy to Minimize the Effect of Residual Gas Volume on ADC in Rat Lungs
Laura Carrero-Gonzalez 1,2 , Thomas Kaulisch 1 , Jesus Ruiz-Cabello 2,3 , Jose Manuel Perez-Sanchez 4 , German Peces-
Barba 5 , Detlef Stiller 1 , Ignacio Rodriguez 2,3
1 Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Baden-Württemberg, Germany; 2 Universidad Complutense de
Madrid, Madrid, Spain; 3 CIBER de Enfermedades Respiratorias, Madrid, Spain; 4 Unité de Recherche en Résonance Magnétique
Médicale (UMR 8081), Univ.Paris-Sud, CNRS, Orsay, France; 5 Fundación Jiménez-Díaz, Madrid, Spain
897. Deflation-Induced Changes in Alveolar-Duct Geometry Via 3 He Lung Morphometry, with Histological
Validation
Adam J Hajari 1,2 , Alex L Sukstanskii 2 , Dmitriy a Yablonskiy 1,2 , Richard a Pierce 3 , Gaetan Deslee 4 , Jason C Woods 1,2
1 Physics, Washington University, St. Louis, MO, United States; 2 Radiology, Washington University, St. Louis, MO, United States;
3 Internal Medicine, Washington University, St. Louis, MO, United States; 4 Service de Pneumologie, INSERM U903, Reims, France
898. Single Lobe Emphysema Induction in the Rat Lung Detected with Diffusion-Weighted 3 He-MRI
Laura Carrero-Gonzalez 1,2 , Thomas Kaulisch 1 , Jesus Ruiz-Cabello 2,3 , Detlef Stiller 1 , Ignacio Rodriguez 2,3
1 Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Baden-Württemberg, Germany; 2 Universidad Complutense de
Madrid, Madrid, Spain; 3 CIBER de Enfermedades Respiratorias, Madrid, Spain
899. Quantitative Imaging of Alveolar Recruitment with Hyperpolarized Gas MRI
Maurizio F. Cereda 1 , Kiarash Emami 2 , Stephen J. Kadlecek 2 , Yi Xin 2 , Puttisarn Mongkolwisetwara 2 , Harilla Profka 2 ,
Amy Barulic 2 , Stephen Pickup 2 , Nicholas N. Kuzma 2 , Masaru Ishii 3 , Hooman Hamedani 2 , Benjamin M. Pullinger 2 ,
Rajat Ghosh 2 , Jennia Rajaei 2 , Clifford S. Deutschman 1 , Rahim R. Rizi 2
1 Anesthesiology & Critical Care, University of Pennsylvania, Philadelphia, PA, United States; 2 Radiology, University of
Pennsylvania, Philadelphia, PA, United States; 3 Otolaryngology–Head & Neck Surgery, Johns Hopkins University, Baltimore, MD,
United States
900. Imaging Regional Alterations of Gas Exchange in a Murine Model of Emphysema
Puttisarn Mongkolwisetwara 1 , Kiarash Emami 1 , Hooman Hamedani 1 , Harilla Profka 1 , Yi Xin 1 , Yinan Xu 1 , Nicholas N.
Kuzma 1 , Stephen J. Kadlecek 1 , Masaru Ishii 2 , Rahim R. Rizi 1
1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Otolaryngology–Head & Neck Surgery, Johns Hopkins
University, Baltimore, MD, United States
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