<strong>Poster</strong> Sessions Govind Nair 1 , Susan Gronka 2,3 , Debbie Lu 2 , Joanne Wuu 2 , Xiaoping P. Hu 1 , Michael Benatar 2 1 Biomedical Imaging & Technology Center, Department of Biomedical Engineering, Emory University & Georgia Institute of Technology, Atlanta, GA, United States; 2 Department of Neurology, School of Medicine, Emory University, Atlanta, GA, United States; 3 University of Miami, Miami, FL, United States 2208. Do Age & Long-Term HIV Infection Control Affect Brain Metabolites? Caroline Rae 1 , Lucette Adeline Cysique 2 , Jae Muyng Lee 3 , Tammy Lane 4 , Kirsten Moffat 5 , Andrew Carr 6 , Bruce James Brew 7 1 Neurosciences Research Australia, University of New South Wales, Sydney, NSW, Australia; 2 Brain Sciences, University of New South Wales, Sydney, NSW, Australia; 3 Neurosciences Research Australia, University of New South Wales, Sydney, Australia; 4 Psychology, Macquarie University, Sydney, Australia; 5 Medical Imaging, St. Vincent's Hospital, Sydney, Australia; 6 Immunology & Infectious Diseases, St. Vincent's Hospital, Sydney, Australia; 7 Neurology, St. Vincent's Hospital, Sydney, Australia 2209. Assessment of Disease Severity in Late Infantile Neuronal Ceroid Lipofuscinosis using Multiparametric MRI Jonathan P. Dyke 1 , Dolan Sondhi 2 , Henning U. Voss 1 , Dikoma C. Shungu 1 , Xiangling Mao 1 , Kaleb Yohay 3 , Stefan Worgall 3 , Neil R Hackett 2 , Charlene Hollmann 2 , Mary E. Yeotsas 2 , Stephen M. Kaminsky 2 , Barry Kosofsky 3 , Linda A. Heier 1 , Ronald G. Crystal 2 , Douglas Ballon 1 1 Radiology, Weill Cornell Medical College, New York, NY, United States; 2 Genetic Medicine, Weill Cornell Medical College, New York, NY, United States; 3 Pediatrics, Weill Cornell Medical College, New York, NY, United States 2210. Voxel-Based T 2 Relaxometry in Prion Disease Enrico De Vita 1,2 , Harpreet Hyare 3,4 , Chris Carswell 3,4 , Andrew Thompson 3,4 , Ana Lukic 3,4 , Tarek Yousry 1,2 , Peter Rudge 3,4 , Simon Mead 3,4 , John Collinge 3,4 , John Thornton 1,2 1 Lysholm Department of Neuroradiology, National Hospital for Neurology & Neurosurgery, UCLH NHS Foundation Trust, London, United Kingdom; 2 Academic Neuroradiological Unit, Department of Brain Repair & Rehabilitation, UCL Institute of Neurology, London, United Kingdom; 3 MRC Prion Unit, Department of Neurodegenerative Diseases, UCL Institute of Neurology, London, United Kingdom; 4 National Prion Clinic, National Hospital for Neurology & Neurosurgery, UCLH NHS Foundation Trust, London, United Kingdom 2211. Glutamatergic & GABAergic Neurotransmission in Manganism using 13 C NMR Spectroscopy Anant Bahadur Patel 1 , Puneet Bagga 1 1 NMR Microimaging & Spectroscopy, Centre for Cellular & Molecular Biology, Hyderabad, Andhra Pradesh, India 2212. In Vivo L-COSY Identifies Neurochemical Changes in Professional Athletes with Repetitive Head Injuries Alexander Peter Lin 1 , Saadallah Ramadan 1 , Robert A. Stern 2,3 , Hayden Nicholas Box 1 , Peter Stanwell 1 , Ann C. McKee 2,3 , Robert Cantu 2 , Christopher Nowinski 2 , Carolyn Elizabeth Mountford 1 1 Center for Clinical Spectroscopy, Brigham & Women's Hospital, Boston, MA, United States; 2 Center for <strong>the</strong> Study of Traumatic Encephalopathy, Boston University School of Medicine, Boston, MA, United States; 3 BU Alzheimer's Disease Center, Boston University School of Medicine, Boston, MA, United States 2213. Distinct Pattern of Atrophy in <strong>the</strong> Different Phenotypes of Progressive Supranuclear Palsy in Magnetic Resonance Imaging Adriane Gröger 1 , Karin Srulijes 1 , Maksym Nechyporenko 1 , Elisabeth Dietzel 1 , Constantin Mänz 2 , Uwe Klose 2 , Walter Mätzler 1 , Daniela Berg 1 1 Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University Tuebingen, Tuebingen, Germany; 2 Department of Diagnostic & Interventional Neuroradiology, University Hospital Tuebingen, Tuebingen, Germany 242 2214. Brain Metabolites in Myotonic Dystrophy Type 1: A 3.0 T Proton Magnetic Resonance Spectroscopy Study Yuhei Takado 1,2 , Hironaka Igarashi 1 , Kenshi Terajima 1,2 , Takayoshi Shimohata 2 , Masaki Okubo 1,3 , Kouichirou Okamoto 1,4 , Masatoyo Nishizawa 1,2 , Tsutomu Nakada 1 1 Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata, Niigata, Japan; 2 Neurology, Brain Research Institute, University of Niigata, Niigata, Japan; 3 Institute of Medicine & Dentistry Basic Radiological Technology, School of Health Sciences, University of Niigata, Niigata, Japan; 4 Neurosurgery, Brain Research Institute, University of Niigata, Niigata, Japan 2215. Distribution of Diffusivity Changes in Subcortical Deep Gray Matter in Prion Diseases Raffaele Lodi 1 , David Neil Manners 1 , Emil Malucelli 1 , Claudia Testa 1 , Giovanni Rizzo 1 , Sabina Capellari 2 , Rosaria Strammiello 2 , Giulia Pierangeli 2 , Pietro Cortelli 2 , Pasquale Montagna 2 , Bruno Barbiroli 1 , Caterina Tonon 1 , Piero Parchi 2 1 MR Spectroscopy Unit, Dept. Internal Medicine, Aging & Nephrology, University of Bologna, Bologna, Italy; 2 Neurological Sciences, University of Bologna, Bologna, Italy 2216. Changes in Iron Concentration of <strong>the</strong> Basal Ganglia in Huntington's Disease using Magnetic Field Correlation Maarten J. Versluis 1,2 , Eve M. Dumas 3 , Simon J. A. van Den Bogaard 3 , Andrew G. Webb 1,2 , Mark A. van Buchem 1 , Ellen P. T. Hart 3 , Matthias J. P. van Osch 1,2 , Jeroen van Der Grond 1 , Raymund A. C. Roos 3 1 Radiology, Leiden University Medical Center, Leiden, Ne<strong>the</strong>rlands; 2 C.J. Gorter Center for High Field MRI, Leiden University Medical Center, Leiden, Ne<strong>the</strong>rlands; 3 Neurology, Leiden University Medical Center, Leiden, Ne<strong>the</strong>rlands
<strong>Poster</strong> Sessions 2217. Assessment of Cerebral Blood Flow in Amyotrophic Lateral Sclerosis using Arterial Spin Labeling MR Imaging Sumei Wang 1 , Lu Wang 1 , Hengyi Rao 2 , Zhengjun Li 2 , Lauren B. Elman 3 , Leo F. McCluskey 3 , Elias R. Melhem 1 , Danny J. J. Wang 4 , John H. Woo 1 1 Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Neurology, Center for Functional Neuroimaging, University of Pennsylvania, Philadelphia, PA, United States; 3 Neurology, University of Pennsylvania, Philadelphia, PA, United States; 4 Neurology, Ahmanson-Lovelace Brain Mapping Center, University of California, Los Angeles, CA, United States 2218. Asymmetric Characteristics of Hippocampus Perfusion & Its Response to Physostigmine Challenge in Gulf War Veterans Xiufeng Li 1 , Jeffrey Spence 2 , David M. Buhner 3 , Robert W. Haley 3 , Richard W. Briggs 1,3 1 Radiology, UT Southwestern Medical Center, Dallas, TX, United States; 2 Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, United States; 3 Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States 2219. Abnormal Striatal Functional Connectivity in Gulf War Illness: Effects of Modulating FcMRI Continuous States Kaundinya Gopinath 1,2 , Wendy Ringe 3 , Luo Ouyang 1 , Kirstine Carter 3 , Binod Thapa-Chhetry 1 , Lisa Butler 1 , Aman Goyal 1 , Parina Gandhi 1 , Yan Fang 1 , Sandeep Ganji 1 , Lei Jiang 1 , Saurabh Vaidya 1 , Richard Briggs 1,2 , Robert Haley 2 1 Department of Radiology, UT Southwestern Medical Center, Dallas, TX, United States; 2 Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States; 3 Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, United States 2220. ASL Hippocampus Perfusion Imaging of Gulf War Veterans: Preliminary Results for National Survey Studies Xiufeng Li 1 , David M. Buhner 2 , Robert W. Haley 2 , Richard Briggs 1,2 1 Radiology, UT Southwestern Medical Center, Dallas, TX, United States; 2 Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States 2221. fMRI Reveals Abnormal Central Sensory Processing in Gulf War Illness Kaundinya Gopinath 1,2 , Lisa Butler 1 , Binod Thapa-Chhetry 1 , Aman Goyal 1 , Parina Gandhi 1 , Yan Fang 1 , Luo Ouyang 1 , Sandeep Ganji 1 , Lei Jiang 1 , Saurabh Vaidya 1 , David Buhner 2 , Wendy Ringe 3 , Richard Briggs 1,2 , Robert Haley 2 1 Department of Radiology, UT Southwestern Medical Center, Dallas, TX, United States; 2 Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States; 3 Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, United States 2222. Basal Ganglia NAA/Cr Ratio & T 2 Differences in a Population-Representative Sample of Veterans with Gulf War Illness Sergey Cheshkov 1,2 , Audrey Chang 2 , Hyeonman Baek 1,2 , Jeffrey Spence 3 , Sandeep Kumar Ganji 2 , Evelyn Babcock 2 , Richard Wallace Briggs 2,4 , Robert W. Haley 4 1 Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States; 2 Radiology, UT Southwestern Medical Center, Dallas, TX, United States; 3 Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, United States; 4 Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States 2223. Fractional Anisotropy is Affected by White Matter Lesions in a TBSS Study of Alzheimer’s Disease Parnesh Raniga 1 , David Raffelt 1 , Alan Connelly 2,3 , Patricia Desmond 4 , Olivier Salvado 1 1 CSIRO Preventative Health National Research Flagship ICTC, The Australian e-Health Research Centre, Brisbane, Queensland, Australia; 2 Brain Research Institute, Florey Neuroscience Institutes (Austin), Melbourne, Victoria, Australia; 3 Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia; 4 Department of Radiology, University of Melbourne, Melbourne, Victoria, Australia 2224. The Standard Deviation (Asd, Normalized Relative Anisotropy at 0 – 1 Scale) Detects Neurodegenerative White Matter Lesions Bettert than <strong>the</strong> Fractional Anisotropy (FA) Joong Hee Kim 1 , Jeffrey J. Neil 2 , Sheng-Kwei Song 1 1 Radiology, Washington University, St. Louis, MO, United States; 2 Neurology & Pediatrics, Division of Pediatric Neurology, Washington University, St. Louis, MO, United States 2225. Longitudinal Evolution of MRI Parameters with Disease Progression in ALS Govind Nair 1 , Debbie Lu 2 , Margaret Walker 2 , John Carew 3 , Xiaoping P. Hu 1 , Michael Benatar 2 1 Biomedical Imaging & Technology Center, Department of Biomedical Engineering, Emory University & Georgia Institute of Technology, Atlanta, GA, United States; 2 Department of Neurology, School of Medicine, Emory University, Atlanta, GA, United States; 3 Biostatistics & Epidemiology, Carolinas HealthCare System, Charlotte, NC, United States 2226. Predict <strong>the</strong> Response of Tinnitus to Cortical Stimulation using Resting-State Functional MRI Gang Chen 1 , Brian Harris Kopell 2 , Wolfgang Gaggl 3 , Rey Ramirez 4 , Klaus Driesslein 4 , Sylvain Baillet 1,4 , Christopher R. Butson 2,4 , Shi-Jiang Li 1,5 1 Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 2 Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States; 3 Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, 243
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