<strong>Poster</strong> Sessions Gastrointestinal & Hepatobiliary Cancer (Clinical Studies) Exhibition Hall Wednesday 13:30-15:30 136 1061. Repeatability of Perfusion & Pure Diffusion Parameters in a Bi-Exponential, Multi-B Diffusion Imaging Approach Sabrina Doblas 1 , Mathilde Wagner 1,2 , Jean-Luc Daire 1,2 , Nathalie Haddad 1,2 , Helena Leitao 2,3 , Ralph Sinkus 1 , Bernard E. Van Beers 1,2 , Valérie Vilgrain 1,2 1 Centre de Recherche Biomédicale Bichat-Beaujon, INSERM U773, Clichy, France; 2 Department of Radiology, Beaujon University Hospital, University Paris Diderot, Clichy, France; 3 Department of Radiology, Hospitais de Universidade de Coimbra, Coimbra, Portugal 1062. The Added Value of a Bi-Exponential Approach for Processing Multi-B Diffusion-Weighted Imaging Data in <strong>the</strong> Diagnosis of Hepatic Tumors Sabrina Doblas 1 , Mathilde Wagner 1,2 , Jean-Luc Daire 1,2 , Nathalie Haddad 1,2 , Helena Leitao 2,3 , Ralph Sinkus 1 , Valérie Vilgrain 1,2 , Bernard E. Van Beers 1,2 1 Centre de Recherche Biomédicale Bichat-Beaujon, INSERM U773, Clichy, France; 2 Department of Radiology, Beaujon University Hospital, University Paris Diderot, Clichy, France; 3 Department of Radiology, Hospitais de Universidade de Coimbra, Coimbra, Portugal 1063. MRI is Superior to 64-Slice CT in Detection of HCC in <strong>the</strong> Cirrhotic Liver Robert F. Hanna 1 , Stephen M. Lagana 2 , Roger K. Moreira 2 , Jean C. Emond 3 , Inna Postolov 4 , Martin R. Prince 1,5 1 Diagnostic Radiology, Columbia University - New York Presbyterian Hospital, New York, NY, United States; 2 Pathology, Columbia University - New York Presbyterian Hospital; 3 Surgery, Columbia University - New York Presbyterian Hospital; 4 Diagnostic Radiology, Columbia University - New York Presbyterian Hospital, New York, NY , United States; 5 Diagnostic Radiology, Weill Cornell Medical Center, New York, NY, United States 1064. Reproducibility of T 2 * MR Imaging & Correlation with Diffusion MR Imaging in Liver Metastasis of Colorectal Cancer E. G. W. ter Voert 1 , L. Heijmen 2 , W. J. G. Oyen 3 , J. H. W. de Wilt 4 , C. J. A. Punt 2 , L. F. de Geus-Oei 3 , H. W. M. van Laarhoven 2 , A. Heerschap 1 1 Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Ne<strong>the</strong>rlands; 2 Medical Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, Ne<strong>the</strong>rlands; 3 Nuclear Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, Ne<strong>the</strong>rlands; 4 Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, Ne<strong>the</strong>rlands 1065. Reproducibility of <strong>the</strong> Apparent Diffusion Coefficient in Liver Metastases of Colorectal Cancer & Assessment of Correlation with FDG-PET. Linda Heijmen 1 , Arend Heerschap 2 , Edwin ter Voert 2 , Wim Oyen 3 , Hans de Wilt 4 , Cees Punt, Lioe-Fee de Geus- Oei 3 , Hanneke van Laarhoven 1 1 Medical Oncology, Radboud University Nijmegen, Medical Centre, Nijmegen, Gelderland, Ne<strong>the</strong>rlands; 2 Radiology, Radboud University Nijmegen, Medical Centre, Nijmegen, Ne<strong>the</strong>rlands; 3 Nuclear Medicine, Radboud University Nijmegen, Medical Centre; 4 Surgery, Radboud University Nijmegen, Medical Centre 1066. Diffusion-Weighted MRI of <strong>the</strong> Liver: Parameters of Acquisition & Analysis & Predictors of Chemo<strong>the</strong>rapy Response Renu M. Stephen 1 , Denise J. Roe, 12 , Abhinav K. Jha 3 , Haiyan Cui 1 , Georgette Frey 1 , Scott Squire 4 , Ted P. Trouard, 45 , Jean P. Galons 4 , Jeff J. Rodriquez 6 , Ma<strong>the</strong>w A. Kupinski 3 , 4 , Eric Outwater 7 , Robert J. Gillies 7 , Alison T. Stopeck 1 1 Arizona Cancer Center, University of Arizona, Tucson, AZ, United States; 2 Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson; 3 College of Optical Sciences, University of Arizona, Tucson; 4 Department of Radiology, University of Arizona, Tucson; 5 Biomedical Engineering, University of Arizona, Tucson; 6 Electrical & Computer Engineering, University of Arizona, Tucson; 7 H.Lee Moffitt Cancer Center & Research Institute, Tampa, FL 1067. An Initial Evaluation of <strong>the</strong> Role of Diffusion Weighted Imaging in <strong>the</strong> Nodal Staging of Rectal MRI Gillian Macnaught 1 , Fat-Wui Poon 2 , S. Viswanathan 1 , Y-T Sim 3 , M. Digby 3 1 Radiology Department, Glasgow Royal Infirmary, NHS Greater Glasgow & Clyde, Glasgow, Scotland, United Kingdom; 2 Radiology Department , Glasgow Royal Infirmary, NHS Greater Glasgow & Clyde, Glasgow, Scotland, United Kingdom; 3 Radiology Department, Stobhill Ambulatory Care Hospital, NHS Greater Glasgow and Clyde, Glasgow, Scotland, United Kingdom 1068. Dynamic Contrast-Enhanced MRI in Rectal Tumours – Initial Reproducibility Measurements at 3T with & Without Bowel Relaxant Geoff Charles-Edwards 1,2 , Jyoti Parikh 1 , Nyree Griffin 1 , Robert Johnstone 1 , David Landau 1 , Andrew Gaya 1 1 Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom; 2 King's College London, London, United Kingdom 1069. Rectal Cancer Neoadjuvant Therapy Assessment with Quantitative Diffusion Imaging ? Olivia Moens 1 , Julie Absil 1 , Anne Demols 2 , Thierry Metens 1 , Celso Matos 1
<strong>Poster</strong> Sessions 1 Magnetic Resonance-Radiology, Université Libre de Bruxelles Hôpital Erasme, Brussels, Belgium; 2 Gastroenterology, Université Libre de Bruxelles Hôpital Erasme, Brussels, Belgium Tumor Perfusion & Permeability Exhibition Hall Thursday 13:30-15:30 1070. DCE-MRI in Tumors at 11.7 Tesla Requires <strong>the</strong> Estimation of Arterial Input Function by Phase Imaging Instead of Magnitude Imaging Anne-Ca<strong>the</strong>rine Fruytier 1 , Julie Magat 1 , Benedicte F. Jordan 1 , Gregory Cron 2 , Bernard Gallez 1 1 Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, University of Louvain, Brussels, Belgium; 2 Ottawa Health Research Institute, Ottawa, Canada 1071. Using DCE-MRI Data to Constrain & Simplify PET Kinetic Modeling Jacob U. Fluckiger 1 , Xia Li 1 , Jennifer Whisenant 1 , Lei Xu 1 , Junzhong Xu 1 , Todd E. Peterson 1 , John C. Gore 1 , Thomas Yankeelov 1 1 Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States 1072. Comparison of <strong>the</strong> Standard Gadolinium Concentration & Signal Difference Methodologies for Computation of Perfusion Parameters in DCE-MRI at Various SNRs Hee Kwon Song 1 , Yiqun Xue 1 , Jiangsheng Yu 1 , Sarah Englander 1 , Hyunseon C Kang 1 , Mark a Rosen 1 1 Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States 1073. Precision & Accuracy of K trans Estimated by Fitting <strong>the</strong> Extended Kety Model Parameters to DCE-MRI Time Course Data is Unaffected by <strong>the</strong> Choice of Optimisation Algorithm or Estimation of T 1 using Linearisation Anita Banerji 1,2 , Josephine H. Naish 1,2 , Giovanni A. Buonaccorsi 1 , Geoff J. M. Parker 1,2 1 Imaging Sciences & Biomedical Engineering, Manchester University, Manchester, United Kingdom; 2 Biomedical Imaging Institute, Manchester, United Kingdom 1074. Anti-Angiogenic Therapy Follow-Up in a Mouse Tumor Model by a Novel 3D Radial Multi-Gradient Echo DCE MRI Technique with Individual AIF Measurement Nadine El Tannir El Tayara 1,2 , Nidhal Ben Achour 1,2 , Christine Walczak 1,2 , Fariba Nemati 3 , Joel Mispelter 1,2 , Didier Decaudin 3 , Julien Vautier 1,2 , Andreas Volk 1,2 1 Research Center, Institut Curie, Orsay, France; 2 U759 INSERM, Orsay, France; 3 Translational Research Department, Institut Curie, Paris, France 1075. Model Fitting of Spatially Smoo<strong>the</strong>d DCE-CT & DCE-MRI Data in Bladder Tumours Penny Louise Hubbard 1,2 , Josephine H. Naish 1,2 , Caleb Roberts 1,2 , Yvonne Watson 1,2 , Karen Davies 1,2 , John C. Waterton 1,3 , Helen Young 3 , John P. Logue 4 , M. Ben Taylor 4 , Geoff J. M. Parker 1,2 1 Imaging Sciences & Biomedical Engineering, The University of Manchester, Manchester, United Kingdom; 2 The Biomedical Imaging Institute, The University of Manchester, Manchester, United Kingdom; 3 AstraZeneca R & D, Alderley Park, Macclesfield, Cheshire, United Kingdom; 4 Christie Hospital, Manchester, United Kingdom 1076. Effects of Flip Angle Variations on <strong>the</strong> Accuracy of Perfusion Parameters in DCE-MRI Jiangsheng Yu 1 , Yiqun Xue 1 , Mark a Rosen 1 , Christina S. Chu 2 , Hee Kwon Song 1 1 Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2 Obstetrics & Gynecology, University of Pennsylvania, Philadelphia, PA, United States 1077. Feasibility of Dual Pharmacokinetic Modeling using Gd-DTPA/MRI & 18 F-FDG/PET Éric Poulin 1 , Étienne Croteau 1 , Réjean Lebel 1 , Luc Tremblay 1 , Roger Lecomte 1 , M'Hamed Bentourkia 1 , Martin Lepage 1 1 Nuclear Medicine & Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada 1078. Use of an Individually Measured Hematocrit in DCE-MRI Studies Caleb Roberts 1,2 , Sarah Hughes 3 , Josephine H. Naish 1,2 , Ka<strong>the</strong>rine Holliday 1,2 , Yvonne Watson 1,2 , Sue Cheung 1,2 , Giovanni A. Buonaccorsi 1,2 , Helen Young 4 , Noel Clarke 3,5 , Geoff J. M. Parker 1,2 1 Imaging Science & Biomedical Engineering, The University of Manchester, Manchester, Greater Manchester, United Kingdom; 2 Biomedical Imaging Institute, The University of Manchester, Manchester, Greater Manchester, United Kingdom; 3 Paterson Institute for Cancer Research, The University of Manchester, Manchester, Greater Manchester, United Kingdom; 4 AstraZeneca, Macclesfield, Cheshire, United Kingdom; 5 Department of Urology, Salford Royal Hospital NHS Foundation Trust, Salford, Greater Manchester, United Kingdom 1079. Analysis of Signal-Adaptive K-Space Acquisition Schemes in Quantitative Dynamic Contrast-Enhanced MRI Ina Nora Kompan 1,2 , Claudia Prieto 3 , Benjamin Richard Knowles 4 , Hendrik Laue 1 , Geoff Charles-Edwards 3 , Matthias Guen<strong>the</strong>r 1,2 , Tobias Schaeffter 3 137
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