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Download the 2011 Program Book - Traditional Poster ... - ismrm

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<strong>Poster</strong> Sessions<br />

968. Evaluation of MR Imaging Biomarkers of <strong>the</strong> Infiltrative & Vascular Phenotype in Orthotopic Murine RG2<br />

Gliomas<br />

Jessica K. R. Boult 1 , Lara Perryman 2 , Gary Box 3 , Chris Jones 2 , Suzanne A. Eccles 3 , Simon P. Robinson 1<br />

1 Cancer Research UK & EPSRC Cancer Imaging Centre, The Institute of Cancer Research & Royal Marsden NHS Trust, Sutton,<br />

Surrey, United Kingdom; 2 Paediatric Oncology, The Institute of Cancer Research, Sutton, Surrey, United Kingdom; 3 Cancer Research<br />

UK Cancer Therapeutics Unit, The Institute of Cancer Research, Sutton, Surrey, United Kingdom<br />

969. A Dynamic Contrast-Enhanced MRI Comparison of <strong>the</strong> Perfusion of Spontaneous & Transplanted Pancreatic<br />

Ductal Adenocarcinoma in Genetically Engineered Mice<br />

Leanne Bell 1 , Davina Honess 2 , Dominick McIntyre 2 , David Tuveson 2<br />

1 CRUK Cambridge Research Institute, Cambridge, United Kingdom; 2 CRUK Cambridge Research Institute, United Kingdom<br />

970. Distribution of DCE-MRI Pharmacokinetic Parameter Maps in Early Murine Mammary Cancer<br />

Xiaobing Fan 1 , Sanaz A. Jansen 2 , Erica J. Markiewicz 1 , Gillian M. Newstead 1 , Gregory S. Karczmar 1<br />

1 Radiology, The University of Chicago, Chicago, IL, United States; 2 Mouse Cancer Genetics <strong>Program</strong>, National Cancer Institute,<br />

Frederick, MD, United States<br />

971. Development of a Spin Echo Gradient Echo Sequence for Simultaneous Assessment of <strong>the</strong> Biomarkers Vessel<br />

Size Index, Relative Blood Volume & Perfusion<br />

Stefan Zwick 1 , Wilfried Reichardt 1 , Claudia Weidensteiner 1 , Dominik von Elverfeldt 1<br />

1 Dept. of Radiology, Medical Physics, University Medical Center, Freiburg, Germany<br />

972. Evaluation of Gd-DTPA Contrast Enhancement of Lung & Metastatic Tumor with Ultra-Short Echo-Time<br />

Imaging<br />

Daisuke Kokuryo 1 , Ichio Aoki 1 , Tsuneo Saga 1<br />

1 Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan<br />

973. DCE-MRI of Genetic Mouse Model of Lung Cancer<br />

Kai Henrik Barck 1 , Anthony Lima 2 , Tim Cao 1 , Rafael Molina 2 , William F. Forrest 3 , Weilan Ye 4 , Leisa Johnson 2 ,<br />

Richard A. D. Carano 1<br />

1 Biomedical Imaging, Genentech, South San Francisco, CA, United States; 2 Molecular Biology, Genentech, South San Francisco, CA,<br />

United States; 3 Biostatistics, Genentech, South San Francisco, CA, United States; 4 Tumor Biology & Angiogenesis, Genentech, South<br />

San Francisco, CA, United States<br />

974. Therapeutic Targeting of NG 2 Proteoglycan with MAb & Pre-Armed NK Cells in Human GBM Evaluated with<br />

Dynamic Enhanced & Diffusion Weighted MRI in Rats<br />

Marte Thuen 1 , Jien Wang 2 , Per Øyvind Enger 2 , Aurelie Poli 3,4 , Guro Løkka 2 , Else Marie Huuse 1 , Frits Thorsen 2 ,<br />

Cecilie Brekke Rygh 2 , Martha Chekenya 2<br />

1 Dep of Circulation & Medical Imaging, Norwegian University of Science & Technology, Trondheim, Norway; 2 Department of<br />

Biomedicine, University of Bergen, Bergen, Norway; 3 Translational Cancer Research, University of Bergen, Norway; 4 Lab for<br />

Immunology & Allergology, CRP sante, Luxembourg, Luxembourg<br />

975. Timing of Anti-Angiogenic Therapy in Brain Tumors using MRI Measures of Relative Cerebral Blood Volume<br />

& Apparent Diffusion Coefficient<br />

Kimberly R. Pechman 1,2 , Deborah L. Donohoe 2,3 , Devyani Bedekar 2,3 , Kathleen M. Schmainda 2,4<br />

1 Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States; 2 Translational Brain Tumor Research <strong>Program</strong>,<br />

Medical College of Wisconsin, Milwaukee, WI, United States; 3 Radiology, Medical College of Wisconsin, Milwaukee, WI, United<br />

States; 4 Radiology & Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States<br />

976. Optimization of Combined Bevacizumab Plus Temozolomide Therapy in Brain Tumor Xenograft Models using<br />

MRI Measures of Relative Cerebral Blood Volume<br />

Kimberly R. Pechman 1,2 , Deborah L. Donohoe 2,3 , Devyani P. Bedekar 2,3 , Kathleen M. Schmaind 2,4<br />

1 Neurosurgery, Medical College of Wisconsin, Millwaukee, WI, United States; 2 Translational Brain Tumor Research <strong>Program</strong>,<br />

Medical College of Wisconsin, Milwaukee, WI, United States; 3 Radiology, Medical College of Wisconsin, Milwaukee, WI, United<br />

States; 4 Radiology & Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States<br />

977. MR Visualization of Depot Vaccines & Immune Activation for Cancer Therapies<br />

Drew R. DeBay 1 , Sarah A. LeBlanc 1 , Genevieve M. Weir 2 , Marc Mansour 2 , Chris V. Bowen 1,3<br />

1 National Research Council - Institute for Biodiagnostics (Atlantic), Halifax, Nova Scotia, Canada; 2 Immunovaccine Inc., Halifax,<br />

Nova Scotia, Canada; 3 Department of Physics & Atmospheric Science, Dalhousie University, Halifax, Nova Scotia, Canada<br />

978. DMSO-Based Contrast as a Potential Intermediate Endpoint Biomarker of GBM Response to Therapy.<br />

Teresa Delgado-Goñi 1,2 , Juana Martin-Sitjar 1,2 , Rui V. Simões 1,2 , Milena Acosta 1,2 , Silvia Lope-Piedrafita 2,3 , Carles<br />

Arús 1,2<br />

127

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