Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
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<strong>PSA</strong> response and time to <strong>PSA</strong><br />
progression (different definitions)<br />
Baseline (B)<br />
Response:<br />
50% below B<br />
C: back<br />
to 50% of<br />
baseline<br />
Nadir (N)<br />
D> N+50%<br />
25<br />
B>N<br />
H. Scher JCO, 2004 (adapted)