Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
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Be aware of your drug’s effect on the marker<br />
Broken Arrow<br />
(Immuno, APC8501)<br />
No effect<br />
(anti-angiogenic drug as sorafeni<br />
Start of Therapy<br />
Lead In Post-therapy<br />
Delayed effect<br />
(Differentiating agent)<br />
Rapid decline<br />
(HT, CT, Suramin)<br />
Scher et al.