Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
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Pooled results<br />
100%<br />
Time to <strong>PSA</strong> progression<br />
(50% increase)<br />
100%<br />
Overall survival<br />
75%<br />
50%<br />
HR=1.6<br />
75%<br />
50%<br />
HR=1.08<br />
25%<br />
Castration<br />
Casodex<br />
0%<br />
0 1 2 3 4<br />
Time (years)<br />
665/2094 (31.8%) progressed<br />
Median : 19 and 30 months (24.9)<br />
25%<br />
0%<br />
Castration<br />
Casodex<br />
0 1 2 3 4<br />
Time (years)<br />
1143 / 2161 (52.9%) died<br />
Median: 26 and 28 months<br />
5