Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
Surrogacy Case Study: Prostate Specific Antigen (PSA ... - Isped
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<strong>PSA</strong> “surrogacy” studies in the<br />
literature<br />
• Many papers titled “<strong>PSA</strong> surrogate” in fact only<br />
demonstrate that <strong>PSA</strong> changes are prognostic for<br />
clinical relapse or death from the disease<br />
• Since 2000, only 12 publications truly dealing<br />
with <strong>PSA</strong> surrogacy