Prevention Guide - Safe Handling of Hazardous Drugs - Irsst

APPENDIX 4 – HAZARDOUS SPILL MANAGEMENT
‣ Discard all of the contaminated material in a thick plastic bag marked “Cytotoxic”. Remove the gown, face
protection and outer pair of gloves (being careful to avoid self-contamination) and place them in the plastic
bag.
‣ Wearing the inner pair of gloves, close the bag and place it in another plastic bag. Remove the inner pair of
gloves and the disposable respirator and place them in the bag before closing it. Dispose of the bag with the
cytotoxic waste. If a powered respirator was used, it must be placed in a separate bag for future cleaning.
‣ Wash your hands with soap and water.
‣ Once the spill has been cleaned up, ask the Hygiene and Sanitation Department to clean the area.
‣ Complete a Spill Report Form (see sample). The Chemical Spill Report Form may also be used.
4.2.2 Spill Inside a Hood
‣ Immediately clean up any small spills (less than 30 mL) inside a hood.
‣ Use a spill kit if the spill is larger than 30 mL or if the contents of an ampoule or vial are involved. It should be
noted that, in general, the workers on the scene are already protected by their personal protective equipment.
‣ Use the thick gloves contained in the kit to collect the glass shards. Place them in the rigid container in the
hood.
‣ Clean and decontaminate the hood before using it again.
‣ Clean the drain placed under the grille of the hood if the spill reached it.
‣ If liquid has penetrated the HEPA filter or if the “clean” side of the filter was contaminated by powder
particles, stop using the hood until it has been decontaminated and the filter replaced.
Sources:
- ASHP. ASHP Guidelines on Handling Hazardous Drugs, Prepublication copy, Dec. 2005. 33 pages
- Occupational and Health Administration. OSHA Technical Manual, Section 6, Chapter 2, 1999 [Web site:
http://www.osha.gov/dts/osta/otm/otm_vi/otm_vi_2.html, accessed May 24, 2006]
PREVENTION GUIDE – SAFE HANDLING OF HAZARDOUS DRUGS ASSTSAS A4-3