Prevention Guide - Safe Handling of Hazardous Drugs - Irsst

10. ADMINISTRATION OF DRUGS
10.3.4 General Administration Measures RATING: +++
Introduce general measures to reduce exposure risks related to the administration of
hazardous drugs.
RECOMMENDATIONS
10.3.4.1 The caregiving staff should check the integrity of hazardous drug containers throughout
the administration process.
10.3.4.2 The workers administering the drugs should use handling and administration techniques
that minimize exposure risks:
‣ use syringes and other devices with a Luer-Lock tip with a proper connector;
‣ place a disposable, absorbent, plastic-backed pad for the containers, on the work table
or under the patient’s arm when applicable, and particularly during drug administration
via the peripheral route (e.g. recommendation not applicable during central
administration through an implantable chamber). This pad will also absorb any
contamination;
‣ wrap the tubing connection site with a piece of gauze when removing the infusion
tubing, to contain any potential leaks (Figure 19);
FIGURE 19
Wrap the tubing connection site with a piece of gauze when removing the infusion tubing
‣ in addition to the sanitary maintenance described, clean the arm of the chair when
contamination is observed;
‣ as often as possible, use a needleless administration system, to reduce the risk of
needlesticks with needles that have been in contact with hazardous drugs;
‣ a closed-circuit administration system (e.g. Phaseal ® , Tevadaptor ® , etc.) may be used,
by connecting it to the devices used in the Pharmacy Department.
ASHP, p. 1189 ♦ CS, p. 68 ♦ CSHP, Section 8.8 ♦ NIOSH, p. 14 ♦ ONS, p. 24-26 ♦ OSHA, Section Vc2
10.3.5 Extravasation RATING: +++
PREVENTION GUIDE – SAFE HANDLING OF HAZARDOUS DRUGS ASSTSAS 10-7