Prevention Guide - Safe Handling of Hazardous Drugs - Irsst

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6. UNPACKING AND STORAGE 6.3.1.3 Local air exhaust should be provided in the unpacking and cleaning area (for example, a work table with an air exhaust grille on the wall). 6.3.1.4 To allow the safe handling of heavy delivery containers, the unpacking table should not have guards. 6.3.1.5 A sink should be installed in or near the unpacking area to allow the cleaning of drug containers. 6.3.1.6 There should be a receptacle for cytotoxic waste in the unpacking area, for the disposal of hazardous drug packaging and contaminated packing cartons. ASHP, p. 6, 7 ♦ NIOSH, p. 12 6.3.2 Protective Equipment RATING: ++ Wear proper protective equipment. RECOMMENDATIONS 6.3.2.1 Exposed workers must wear a protective gown and two (2) pairs of gloves (see 4.1.7.7) when unpacking and cleaning hazardous drugs, from the opening of the delivery containers to the placing of the drugs in their storage space. If there is a risk of splashing, face protection must be worn (see 4.1.7.10). Storage workers may wear a protective gown and one pair of gloves when handling hazardous drug containers. 6.3.2.2 The wearing of a respirator is not required for opening and unpacking drug parcels and containers if the unpacking area has a local air exhaust system. If it does not, workers should wear a respirator against dust (NIOSH-approved Class N-95 or N-100 full-face or half-face mask (see 4.1.7.11)). ASHP, p. 1175, 1178, 1188 ♦ LSST, Art. 49 and 51 ♦ NIOSH, p. 12 6-2 ASSTSAS PREVENTION GUIDE – SAFE HANDLING OF HAZARDOUS DRUGS
6. UNPACKING AND STORAGE 6.3.3 Unpacking and Cleaning Procedure RATING: ++ Establish an unpacking and cleaning procedure. RECOMMENDATIONS 6.3.3.1 Workers assigned to unpacking should check the integrity of the delivery containers and their contents at the time of unpacking. In the event of breakage or leaking, they should treat the damaged contents as a spill (see 12.3.4.8). 6.3.3.2 Workers assigned to unpacking should cover the work table with a disposable, plasticbacked, absorbent pad on which to place the containers. This pad will also absorb any contamination. 6.3.3.3 The hazardous drug containers should be cleaned at the time of unpacking, before being placed in storage. To do so, the hazardous drugs must be removed from their individual packaging: ‣ if the drug is light-sensitive, provide a storage system limiting exposure to light. ‣ note that drugs removed from their packaging often cannot be returned to the manufacturer. ‣ do not remove the plastic film covering certain vials; this film is added by the manufacturer at the end of the production line, in order to limit contamination of the outside of the vials by hazardous drugs. If containers are not cleaned at the time of unpacking, they should be stored separately from those which have been cleaned. Uncleaned containers should be cleaned before entering the preparation circuit. 6.3.3.4 All hazardous drug containers should be cleaned to reduce external contamination from the distributor or manufacturer. There is no ideal universal solvent. However, tests performed by the INSPQ at the Committee’s request have confirmed that the use of a disposable cloth and a household detergent and water solution was effective in removing contamination on the outside of the vials. The use of premoistened towelettes (e.g. Wet-Ones) was also shown to be effective. (Note: The tests were done with cyclophosphamide. The cloth or towelette used was discarded after cleaning four vials.) However, this procedure must not increase the risk of incidents/accidents due to damage to the hazardous drug label. The wearing of protective gloves is the first step to be taken prior to the decontamination of drugs. (+) 6.3.3.5 Plastic bins and safe carts (i.e., which limit the risk of falls/breakage) should be used for transporting hazardous drugs. ASHP, p. 1175, 1183 ♦ NIOSH, p. 12 ♦ OPQ, Section 6.2.3 PREVENTION GUIDE – SAFE HANDLING OF HAZARDOUS DRUGS ASSTSAS 6-3
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Prevention Guide Safe Handling of H
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Page 7 and 8: Table of Contents PREAMBLE ........
Page 9 and 10: List of Tables Table 1 Medication C
Page 11: PREAMBLE In September 2004, the Uni
Page 14 and 15: 1. INTRODUCTION 1.1.1 Survey Regard
Page 16 and 17: 1. INTRODUCTION 1.3 Guide Structure
Page 19 and 20: 2. RISKS RELATED TO THE USE OF HAZA
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Page 45 and 46: 4. GENERAL PREVENTIVE MEASURES Tabl
Page 47: 4. GENERAL PREVENTIVE MEASURES Gras
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Page 70 and 71: 8. DRUG PREPARATION The product nev
Page 72 and 73: 8. DRUG PREPARATION ‣ avoid sudde
Page 74 and 75: 8. DRUG PREPARATION or “Caution
Page 76 and 77: 8. DRUG PREPARATION 8.3.9 Preparing
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Page 92 and 93: 10. ADMINISTRATION OF DRUGS 10.3.10
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Page 99 and 100: 11. PATIENT CARE 11 PATIENT CARE 11
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12. MANAGEMENT OF WASTE, ACCIDENTAL
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13. HYGIENE AND SANITATION 13.2 Exp
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14. LAUNDRY 14 LAUNDRY 14.1 Issues
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15. MEDICAL, BIOLOGICAL AND ENVIRON
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15. MEDICAL, BIOLOGICAL AND ENVIRON
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16. REFERENCES 16 REFERENCES AHQ [1
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16. REFERENCES Nygren O., Lundgren
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APPENDIX 1 - GLOSSARY APPENDIX 1- G
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APPENDIX 1 - GLOSSARY TERMS DEFINIT
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APPENDIX 1 - GLOSSARY TERMS DEFINIT
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APPENDIX 2 - LIST OF HAZARDOUS DRUG
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APPENDIX 3 - SURVEY REGARDING PRACT
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APPENDIX 4 - HAZARDOUS SPILL MANAGE
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APPENDIX 4 - HAZARDOUS SPILL MANAGE
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5. MEASUREMENT OF WORK SURFACE CONT
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