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Prevention Guide - Safe Handling of Hazardous Drugs - Irsst

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4. GENERAL PREVENTIVE MEASURES<br />

cleaned) (Figure 4). For further information, see CSA standard Z94.3.1-02: Protective<br />

Eyewear: A User’s <strong>Guide</strong>. As the shield only protects the eyes, a fluid-resistant<br />

surgical mask should also be worn.<br />

FIGURE 4<br />

Disposable eye shield: the frame is reusable and must be cleaned. The lens is discarded without cleaning.<br />

‣ Removing the protection: the face shield or protective eyewear must be removed by<br />

touching only the components that go around the head or ears; avoid touching the<br />

surface or sides <strong>of</strong> the shield or eyewear, as they may be contaminated.<br />

4.1.7.11 Respiratory Protection Apparatus (RPA)<br />

When required, a respiratory protection apparatus (respirator) must be used. The type <strong>of</strong><br />

respirator depends on what is known regarding the risks and nature <strong>of</strong> the contaminant. In<br />

the case <strong>of</strong> hazardous drugs, there is no acceptable exposure value, the dose-effect<br />

relationship is not known and, in some circumstances, there is reason to be concerned<br />

about the vapours that may be generated by these drugs. We have therefore followed the<br />

principle <strong>of</strong> prudent practice in formulating our recommendations, i.e., it is better to err on<br />

the side <strong>of</strong> caution (while remaining realistic) when implementing the various<br />

recommendations.<br />

‣ For the majority <strong>of</strong> tasks involving the handling <strong>of</strong> hazardous drugs, dust protection<br />

would be sufficient (full or half NIOSH-approved N-95 or N-100 filtering<br />

respirator/mask). In the presence <strong>of</strong> vapours, a respirator with chemical cartridges for<br />

organic vapours, combined with a dust filter, may be necessary (Figure 5). In the<br />

specific event <strong>of</strong> a spill, it may be appropriate (depending on the extent <strong>of</strong> the spill) to<br />

use a motorized or self-contained respirator.<br />

FIGURE 5<br />

Respirator with chemical cartridges and dust filter<br />

‣ The choice <strong>of</strong> respirator must be made as part <strong>of</strong> the institution’s Respiratory<br />

Protection Program, which should include a risk analysis, as well as the choice <strong>of</strong><br />

respirators and the related training. A fit test is required to determine the appropriate<br />

size and model <strong>of</strong> the respirator. Thereafter, a seal-check test must be performed before<br />

each use. The Regulation regarding Occupational Health and <strong>Safe</strong>ty specifies that the<br />

Respiratory Protection Program must be established in accordance with CSA standard<br />

Z94.4-93 (Sect. 45) and describes the conditions <strong>of</strong> use (Sect. 46).<br />

For additional information regarding respirators, see the <strong>Guide</strong> pratique de protection<br />

PREVENTION GUIDE – SAFE HANDLING OF HAZARDOUS DRUGS ASSTSAS 4-7

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