discrete-event simulation in clinical trials - Institut für Statistik ...
discrete-event simulation in clinical trials - Institut für Statistik ...
discrete-event simulation in clinical trials - Institut für Statistik ...
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Open questions<br />
‣ Prediction of a new trajectory for a new case<br />
(imcomplete) us<strong>in</strong>g the population <strong>in</strong>formation <strong>in</strong> PK<br />
(Bayesian prediction)<br />
Interest<strong>in</strong>g<br />
implications <strong>in</strong> adjust<br />
the drug dose to the<br />
patient, m<strong>in</strong>imize risk<br />
of toxicity, <strong>in</strong>crease<br />
efficacy<br />
Prior<br />
Posterior<br />
SAS<br />
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