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Annual Report 2006

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Insect and Animal Sciences Division<br />

The Insect and Animal Sciences Division<br />

consists of the following six departments.<br />

The Developmental Biology Department is<br />

conducting research to elucidate the<br />

physiological functions of germ cell lines and<br />

the hormonal mechanism underlying growth<br />

regulation, and to develop embryonic technologies<br />

as well. These researches focus on several<br />

invertebrates and vertebrates.<br />

The Molecular Biology and Immunology<br />

Department is concerned with the molecular<br />

events involved in the signaling for<br />

antibacterial peptide synthesis in insects and<br />

signaling of cytokines and T cell receptors in<br />

mammals, the functional analysis of macrophage<br />

/microglia, hematopoietic stem cells and T cell<br />

subsets, the genetic mechanisms underlying<br />

complex disease traits, and the development<br />

and improvement of transgenic animal<br />

technology. Major research on cytokine<br />

signaling in the mammalian immune system,<br />

innate immune system in insect, the<br />

transformation of spermatogenic cells in vivo<br />

and genetic analysis of multi-factorial are being<br />

conducted.<br />

The Physiology and Genetic Regulation<br />

Department aims to elucidate the mechanisms<br />

of unique physiological phenomena observed in<br />

insects and animals. The studies include<br />

analyses of neural functions including brain,<br />

metabolic regulation, and physiological bases<br />

for adaptation to environment, perception and<br />

function of behavior regulating chemicals, cell<br />

differentiation and the genes regulating them,<br />

in both invertebrates and vertebrates.<br />

The research activities of the Insect<br />

Genetics and Evolution Department are mainly<br />

focused on molecular and conventional genetics<br />

of insects including silkworm, biochemical<br />

analyses of insect-plant interaction,<br />

characterization and breeding of natural<br />

enemies, and basic and applied studies on insect<br />

-associated microbes including pathogens and<br />

symbiotes.<br />

The Insect Biomaterial and Technology<br />

Department is carrying out research which<br />

aims to develop the biomimetic techniques of<br />

insects and their utilization such as the sugar<br />

reception of the flesh fly, and to clarify the<br />

characteristics of insect-born biomaterials for<br />

the development of new technologies.<br />

The major targets of the Insect<br />

Biotechnology and Sericology Department are<br />

the development of functional insect cell lines<br />

and transgenic insects, large-scale production of<br />

useful substances using the transgenic insect<br />

systems, and the development of new silk<br />

materials which are good for healthful and<br />

wealthy human life by developing new<br />

sericultural technologies including breeding of<br />

characteristic new varieties of silkworms.<br />

The major research topics for 2005 from<br />

these six departments in the Insect and Animal<br />

Sciences Division are as follows:

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