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NHMRC Glaucoma Guidelines - ANZGIG

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<strong>NHMRC</strong> GUIDELINES FOR THE SCREENING, PROGNOSIS, DIAGNOSIS, MANAGEMENT AND PREVENTION OF GLAUCOMA<br />

Chapter 1 – Recommendations and Evidence statements<br />

Recommendation<br />

Good Practice Point<br />

• Peripheral iridoplasty might<br />

be useful after iridotomy in<br />

individual cases. Consider<br />

cataract extraction and<br />

ongoing IOP control,<br />

including trabeculectomy<br />

as required.<br />

Recommendation 14<br />

Ensure patients are<br />

aware of risks<br />

and symptoms<br />

of angle-closure<br />

and can access care<br />

urgently as necessary<br />

Evidence Statements<br />

Surgical options for specific glaucoma classification<br />

and stages – Established open angle glaucoma<br />

Evidence strongly supports surgery as being at least as<br />

effective as medication for reducing intraocular pressure<br />

in established open angle glaucoma.<br />

Evidence strongly supports using surgery when target<br />

intraocular pressure is not being achieved with two or more<br />

medications, or adherence is problematic, and when laser<br />

has failed or is not likely to succeed.<br />

Surgical options for specific glaucoma classification<br />

and stages – Angle closure<br />

Evidence supports surgical iridectomy as a second choice<br />

treatment for patients with acute angle closure, when<br />

primary laser iridotomy cannot be performed.<br />

Expert/consensus opinion suggests the value of cataract<br />

extraction or drainage surgery for patients with angle closure.<br />

Surgical options for specific glaucoma classification<br />

and stages – Filtering surgery<br />

Evidence supports using filtration surgery as a third choice<br />

treatment in most patients, due to the inherent risks with<br />

any invasive procedure.<br />

Evidence supports using filtration surgery for patients<br />

with moderate or advanced glaucoma, due to its success<br />

in lowering intraocular pressure. This is especially relevant<br />

to patients with eyes with high pressure conditions<br />

(over 30mmHg), or patients with eyes resistant to other<br />

forms of therapy.<br />

Surgical options for specific glaucoma classification<br />

and stages – Anti-fibrotic medications<br />

Evidence supports using intra-operative and post-operative<br />

anti-fibrotics to reduce the risk of failure for patients<br />

undergoing incisional surgery.<br />

Surgical options for specific glaucoma classification<br />

and stages – <strong>Glaucoma</strong> drainage devices<br />

Evidence strongly supports using tube surgery for long-term<br />

intraocular pressure control. This is an appropriate first-choice<br />

surgery in patients:<br />

−−<br />

with eyes at higher risk of failure from trabeculectomy<br />

−−<br />

who have failed trabeculectomy<br />

−−<br />

with Iridocorneal Endothelial syndrome<br />

−−<br />

with various forms of uveitic (inflammatory) glaucoma, or<br />

−−<br />

with aphakic glaucoma.<br />

Surgical options for specific glaucoma classification<br />

and stages – Cataract surgery<br />

Evidence supports using cataract surgery to open the<br />

angle in most patients with primary angle closure, when<br />

laser procedures have been inadequate. This is believed to<br />

improve the safety of subsequent drainage surgery.<br />

Evidence<br />

Statement<br />

Grade<br />

B<br />

B<br />

B<br />

B<br />

B<br />

B<br />

B<br />

B<br />

National Health and Medical Research Council 25

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