Jozef Hodyl PhD Thesis - Theses - Flinders University

3637The loading of macrocycle obtained for these materials was 0.28 mmol ofmacrocycle per gram of functionalised silica for 36 and 0.32 mmol of macrocycle pergram of functionalised silica for 37. Immobilisation of macrocycles in materials 35,36 and 37 demonstrates that it is possible to graft bulky molecules onto linkerfunctionalised silica with good results.1.4.2 Receptor complexes tethered to solid supportsMany studies involving immobilisation of a receptor onto a silica surface concern thetethering of either calixarene or cyclodextrin moieties. 154, 155 An example is from anaccount published in 2002 by Katz and co-workers. 156 They reported the tethering ofp-tert-butyl-calix[4]arene to a silica surface initially modified with SiCl 4(tetrachlorosilane) to obtain 38 with a coverage of calixarene per gram of silicamaterial of 0.27 mmol g -1 .30